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[미국특허] Polymethylmethacrylate delivery system for bone morphogenetic protein 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-035/12
  • A61K-037/00
  • A01N-063/02
출원번호 US-0569031 (1984-01-09)
발명자 / 주소
  • Urist Marshall R. (Pacific Palisades CA)
출원인 / 주소
  • Regents of the University of California (Berkeley CA 02)
인용정보 피인용 횟수 : 72  인용 특허 : 1

초록 ▼

A delivery system for delivering bone morphogenetic protein to induce formation of new bone in viable tissue. The delivery composition comprises substantially pure bone morphogenetic protein and polymethylmethacrylate and it is prepared by admixing the bone morphogenetic protein and polymethylmethac

대표청구항

A composition comprising substantially pure bone morphogenetic protein and a polymeric acrylic ester.

이 특허에 인용된 특허 (1) 인용/피인용 타임라인 분석

  1. Urist Marshall R. (Pacific Palisade CA), Bone morphogenetic protein process.
    상세보기

이 특허를 인용한 특허 (72) 인용/피인용 타임라인 분석

  1. Larsen, Flemming; Wahlers, Ulla, Antibodies to MASP-2.
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  2. Larsen, Flemming; Wahlers, Ulla, Antibodies to MASP-2.
    상세보기
  3. Michelson,Gary Karlin, Apparatus and method for anterior spinal stabilization.
    상세보기
  4. Michelson, Gary Karlin, Apparatus for insertion into an implantation space.
    상세보기
  5. Chesterfield Michael P. (Norwalk CT) Torgerson Robert D. (Branford CT), Bioabsorbable implant material.
    상세보기
  6. Guire Patrick E. (Eden Prairie MN), Biocompatible coating for solid surfaces.
    상세보기
  7. Alan M. Polson ; Deryl D. Swanbom ; Richard L. Dunn ; Charles P. Cox ; Richard L. Norton ; Bryan K. Lowe ; Kenneth S. Peterson, Biodegradable implant precursor.
    상세보기
  8. Dunn Richard L. (Fort Collins CO) Tipton Arthur J. (Fort Collins CO) Southard George L. (Fort Collins CO) Rogers Jack A. (Fort Collins CO), Biodegradable polymer composition.
    상세보기
  9. Norton Richard L. (Fort Collins CO) Knight Stephen Michael Gregory (Fort Collins CO) Tipton Arthur J. (Birmingham AL), Biodegradable polymeric composition.
    상세보기
  10. Comfort Christopher J., Bone augmentation for prosthetic implants and the like.
    상세보기
  11. Comfort Christopher J., Bone augmentation for prosthetic implants and the like.
    상세보기
  12. Coates,Bradley J.; Van Hoeck,James; Poyner,Jeffrey W., Bone grafts.
    상세보기
  13. John Pafford ; Lawrence M. Boyd ; William F. McKay ; Eddie F. Ray, III ; James E. Van Hoeck, Bone grafts.
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  14. Pafford, John; Boyd, Lawrence M.; McKay, William F.; Ray, III, Eddie F.; Van Hoeck, James E., Bone grafts.
    상세보기
  15. Kiefer Michael C. (Clayton CA) Masiarz Frank R. (San Francisco CA) Barr Philip J. (Oakland CA), Bone morphogenetic protein expression and DNA.
    상세보기
  16. Dunn, Richard L.; Yarborough, Cody L., Coupling syringe system and methods for obtaining a mixed composition.
    상세보기
  17. Michelson, Gary Karlin, Device and method for locking a screw with a bendable plate portion.
    상세보기
  18. Dunn,Richard L., Emulsions for in-situ delivery systems.
    상세보기
  19. Voellmicke,John C.; Connolly,Stephen W.; Kadiyala,Sudhakar; Bruder,Scott P.; Urbahns,David; Tanaka,Kazuna; Kapec,Jeffrey; Naoi,Yukiko, Graft delivery system.
    상세보기
  20. Brook Michael G. (Chessington GB2), Hydrophilic copolymers for wound dressings and other biomedical uses.
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  21. Beyer, Jr., Wayne F.; Hyde-DeRuyscher, Robin; Hamilton, Paul T.; Benson, Ray Edward, IFBM's to promote the specific attachment of target analytes to the surface of orthopedic implants.
    상세보기
  22. Beyer, Jr., Wayne F.; Hyde-DeRuyscher, Robin; Hamilton, Paul T.; Benson, Ray Edward, IFBM's to promote the specific attachment of target analytes to the surface of orthopedic implants.
    상세보기
  23. Beyer, Jr., Wayne F.; Hyde-DeRuyscher, Robin; Hamilton, Paul T.; Benson, Ray Edward, IFBM's to promote the specific attachment of target analytes to the surface of orthopedic implants.
    상세보기
  24. Michelson, Gary K., Implant with openings adapted to receive bone screws.
    상세보기
  25. Michelson, Gary K., Implant with openings adapted to receive bone screws.
    상세보기
  26. Michelson, Gary K., Implant with openings adapted to receive bone screws.
    상세보기
  27. Michelson,Gary K., Implant with trailing end adapted to receive bone screws.
    상세보기
  28. Zdeblick, Thomas; Ray, III, Eddie; Boyd, Lawrence M., Interbody fusion device and method for restoration of normal spinal anatomy.
    상세보기
  29. Zdeblick,Thomas; Ray, III,Eddie; Boyd,Lawrence M., Interbody fusion device and method for restoration of normal spinal anatomy.
    상세보기
  30. Michelson, Gary Karlin, Interbody spinal fusion implants.
    상세보기
  31. Michelson, Gary K., Interbody spinal implant with trailing end adapted to receive bone screws.
    상세보기
  32. Shah, Gretchen Dougherty; Bae, Hyun; Lakin, Ryan C.; Hawkins, Nathaniel E., Intervertebral implant and associated method.
    상세보기
  33. Lakin, Ryan Cameron; Bailey, Kirk J.; Blumers, John M., Intervertebral implantation apparatus.
    상세보기
  34. James E. Van Hoeck ; Troy McDonald ; Bradley J. Coates ; Regis W. Haid, Jr. ; Stephen E. Heim ; Kevin Foley ; Eugene C. Eckstein, Intervertebral spacers.
    상세보기
  35. Van Hoeck, James E.; McDonald, Troy; Coates, Bradley J.; Haid, Jr., Regis W.; Heim, Stephen E.; Foley, Kevin; Eckstein, Eugene C., Intervertebral spacers.
    상세보기
  36. Van Hoeck,James E.; McDonald,Troy; Coates,Bradley J.; Haid, Jr.,Regis W.; Heim,Stephen E.; Foley,Kevin; Eckstein,Eugene C., Intervertebral spacers.
    상세보기
  37. Chern, Rey T.; Zingerman, Joel R., Liquid polymeric compositions for controlled release of bioactive substances.
    상세보기
  38. Jensenius, Jens Chr.; Thiel, Steffen, MASP 2, a complement-fixing enzyme, and uses for it.
    상세보기
  39. Jensenius, Jens Chr.; Thiel, Steffen, MASP-2, a complement fixing enzyme, and uses for it.
    상세보기
  40. Gayer Gregory G. ; Comfort Christopher J., Method and apparatus for augmentating osteointegration of prosthetic implant devices.
    상세보기
  41. Gregory G. Gayer ; Christopher J. Comfort, Method and apparatus for augmenting osteointegration of prosthetic implant devices.
    상세보기
  42. Polson Alan M. ; Swanbom Deryl D. ; Dunn Richard L. ; Cox Charles P. ; Norton Richard L. ; Lowe Bryan K. ; Peterson Kenneth S., Method and composition for treating a bone tissue defect.
    상세보기
  43. Anderson H. Clarke, Method for inducing bone formation using an extract of human osteosarcoma cell line SAOS-2.
    상세보기
  44. Anderson H. Clarke ; Hsu Howard H. T., Method for inducing bone formation using an extract of human osteosarcoma cell line SAOS-2.
    상세보기
  45. Guire Patrick E. (Eden Prairie MN), Method of improving the biocompatibility of solid surfaces.
    상세보기
  46. Alleyne, Neville; Young, Stuart, Method of treating spinal internal disk derangement.
    상세보기
  47. Alleyne, Neville; Young, Stuart, Method of treating spinal internal disk derangement.
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  48. Alleyne, Neville; Young, Stuart, Method of treating spinal internal disk derangement.
    상세보기
  49. Alleyne, Neville; Young, Stuart, Method of using an implant for treament of ligaments and tendons.
    상세보기
  50. Alleyne, Neville; Young, Stuart, Methods and compositions for minimally invasive capsular augmentation of canine coxofemoral joints.
    상세보기
  51. Thomas Zdeblick ; Thomas McGahan, Methods and instruments for interbody fusion.
    상세보기
  52. Zdeblick Thomas ; McGahan Thomas, Methods and instruments for interbody fusion.
    상세보기
  53. Zdeblick, Thomas; McGahan, Thomas, Methods and instruments for interbody fusion.
    상세보기
  54. Zdeblick, Thomas; McGahan, Thomas, Methods and instruments for interbody fusion.
    상세보기
  55. Zdeblick, Thomas; McGahan, Thomas, Methods and instruments for interbody fusion.
    상세보기
  56. Gruskin, Elliott A.; Buechter, Douglas D.; Zhang, Guanghui; Connelly, Kevin, Methods for producing extracellular matrix proteins.
    상세보기
  57. Demopulos, Gregory A.; Dudler, Thomas; Schwaeble, Hans-Wilhelm, Methods for treating conditions associated with MASP-2 dependent complement activation.
    상세보기
  58. Demopulos, Gregory A.; Dudler, Thomas; Schwaeble, Hans-Wilhelm, Methods for treating conditions associated with MASP-2 dependent complement activation.
    상세보기
  59. Demopulos, Gregory A.; Dudler, Thomas; Schwaeble, Hans-Wilhelm, Methods for treating conditions associated with MASP-2 dependent complement activation.
    상세보기
  60. Demopulos, Gregory A.; Dudler, Thomas; Schwaeble, Hans-Wilhelm, Methods for treating conditions associated with MASP-2 dependent complement activation.
    상세보기
  61. Schwaeble, Hans-Wilhelm; Tedford, Clark E.; Parent, James B.; Dudler, Thomas; Demopulos, Gregory A., Methods for treating conditions associated with MASP-2 dependent complement activation.
    상세보기
  62. Schwaeble, Hans-Wilhelm; Dudler, Thomas; Tedford, Clark E.; Parent, James B.; Demopulos, Gregory A., Methods for treating disseminated intravascular coagulation by inhibiting MASP-2 dependent complement activation.
    상세보기
  63. Draenert Klaus,DEX ; Wahlig Helmut,DEX, Multi-component material and process for its preparation.
    상세보기
  64. Elliott A. Gruskin ; Douglas D. Buechter ; Guanghui Zhang ; Kevin Connelly, Nucleic acids encoding extracellular matrix proteins.
    상세보기
  65. Zdeblick Thomas ; McKay William F., Osteogenic fusion devices.
    상세보기
  66. Agrawal C. Mauli ; Athanasiou Kyriacos A., Permeable compositions and methods for their preparation.
    상세보기
  67. Schmitz John P. (Columbia MD), Polyactic-polyglycolic acid copolymer combined with decalcified freeze-dried bone for use as a bone repair material.
    상세보기
  68. Caplan Arnold I. (1300 Oakridge Dr. Cleveland Heights OH 44121) Syftestad Glenn T. (3660 Warrensville Center Rd. #101 Shaker Heights OH 44122), Process of adapting soluble bone protein for use in stimulating osteoinduction.
    상세보기
  69. Zdeblick, Thomas; McKay, William F.; Boyd, Larry; Ray, III, Eddie; McGahan, Thomas, Spinal fusion implants and tools for insertion and revision.
    상세보기
  70. Gary Karlin Michelson, Spinal implant with bone screws.
    상세보기
  71. Stone Roger Lee (Hamilton OH), Therapeutic compositions for osteoinduction.
    상세보기
  72. Agrawal C. Mauli ; Athanasiou Kyriacos A., Variable permeability bone implants, methods for their preparation and use.
    상세보기

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