$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Biodegradable organic polymer delivery system for bone morphogenetic protein 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-037/02
  • A61K-035/32
  • C07G-007/00
출원번호 US-0579034 (1984-02-10)
발명자 / 주소
  • Urist Marshall R. (Pacific Palisades CA)
출원인 / 주소
  • University of California (Berkeley CA 02)
인용정보 피인용 횟수 : 218  인용 특허 : 3

초록

Disclosed is a biodegradable polylactic acid polymer delivery system for delivery of bone morphogenic protein (BMP) to induce formation of new bone in viable tissue. The delivery composition is substantially pure BMP in combination with a biodegradable polylactic acid polymer and it is prepared by a

대표청구항

A composition comprising substantially pure BMP and physiologically acceptable, biodegradable polylactic acid polymer.

이 특허에 인용된 특허 (3)

  1. Jefferies Steven R. (5802 Leith Walk Baltimore MD 21239), Bone graft material for osseous defects and method of making same.
  2. Naficy Sadeque S. (Houston TX), Breast prosthesis with filling valve.
  3. Smestad Thomas L. (San Jose CA), Nonstress-bearing implantable bone prosthesis.

이 특허를 인용한 특허 (218)

  1. Schmieding, Reinhold, Allograft bone or synthetic wedges for osteotomy.
  2. Michelson,Gary K., Anterior cervical plate system.
  3. Larsen, Flemming; Wahlers, Ulla, Antibodies to MASP-2.
  4. Larsen, Flemming; Wahlers, Ulla, Antibodies to MASP-2.
  5. Michelson,Gary Karlin, Apparatus and method for anterior spinal stabilization.
  6. Michelson, Gary Karlin, Apparatus for insertion into an implantation space.
  7. Ammann, Kelly; Novak, Vincent P.; Schneider, Robert E.; Taber, Justin R., Apparatus for performing an open wedge, high tibial osteotomy.
  8. Ammann, Kelly; Novak, Vincent P.; Schneider, Robert; Burns, Ralph E., Apparatus for performing an open wedge, high tibial osteotomy.
  9. Kloke, Tim M.; Keough, Steven J.; Lockwood, Nathan; Gardner, Margaret R.; Hergenrother, Robert W.; Chappa, Ralph A., Beaded wound spacer device.
  10. Alan M. Polson ; Deryl D. Swanbom ; Richard L. Dunn ; Charles P. Cox ; Richard L. Norton ; Bryan K. Lowe ; Kenneth S. Peterson, Biodegradable implant precursor.
  11. Dunn Richard L. (Fort Collins CO) Tipton Arthur J. (Fort Collins CO) Southard George L. (Fort Collins CO) Rogers Jack A. (Fort Collins CO), Biodegradable polymer composition.
  12. Norton Richard L. (Fort Collins CO) Knight Stephen Michael Gregory (Fort Collins CO) Tipton Arthur J. (Birmingham AL), Biodegradable polymeric composition.
  13. Gerhart Tobin N. (Brookline MA) Hayes Wilson C. (Lincoln MA), Bioerodable implant composition.
  14. Schmidmaier, Gerhard; Raschke, Michael; Stemberger, Axel, Biologically active implants.
  15. Schmidmaier,Gerhard; Raschke,Michael; Stemberger,Axel, Biologically active implants.
  16. Comfort Christopher J., Bone augmentation for prosthetic implants and the like.
  17. Comfort Christopher J., Bone augmentation for prosthetic implants and the like.
  18. Kuberasampath Thangavel (Medway MA) Ridge Richard J. (Acton MA), Bone collagen matrix for zenogenic implants.
  19. Scarborough, Nelson L., Bone graft and guided bone regeneration method.
  20. Thorne, Kevin J., Bone growth particles and osteoinductive composition thereof.
  21. Hair, Gregory A.; Boden, Scott D., Bone mineralization proteins, DNA, vectors expression systems.
  22. Gregory A. Hair ; Scott D. Boden, Bone mineralization proteins, DNA, vectors, expression systems.
  23. Hair Gregory A. ; Boden Scott D., Bone mineralization proteins, DNA, vectors, expression systems.
  24. Hair, Gregory A.; Boden, Scott D., Bone mineralization proteins, DNA, vectors, expression systems.
  25. Kiefer Michael C. (Clayton CA) Masiarz Frank R. (San Francisco CA) Barr Philip J. (Oakland CA), Bone morphogenetic protein expression and DNA.
  26. Schenck Robert C. (Comfort TX) Agrawal C. Mauli (San Antonio TX), Bone prosthesis.
  27. Jones A. Alexander M., Bone screw shimming and bone graft containment system and method.
  28. Akella, Rama; Garrett, Ian Ross; Wen, Hai Bo; Li, Shuliang; Acker, Dean M.; Wilhelm, Nichole, Bone void fillers.
  29. Li, Rebecca; Seeherman, Howard; Tofighi, Aliassghar, Calcium phosphate delivery vehicles for osteoinductive proteins.
  30. Li, Rebecca; Seeherman, Howard; Tofighi, Aliassghar, Calcium phosphate delivery vehicles for osteoinductive proteins.
  31. Kloke, Tim M.; Keough, Steven J.; Lockwood, Nathan; Gardner, Margaret R.; Hergenrother, Robert W.; Chappa, Ralph A., Coating composition.
  32. Hubbell, Jeffrey A.; Pathak, Chandrashekhar P.; Sawhney, Amarpreet S.; Desai, Neil P.; Hill, Jennifer L.; Hossainy, Syed F. A., Coating substrates by polymerizing macromers having free radical-polymerizable substituents.
  33. Sierra David H., Collagen-polymer matrices with differential biodegradability.
  34. Sierra David H., Collagen-polymer matrices with differential biodegradability.
  35. Thorne, Kevin J., Composition and process for bone growth and repair.
  36. Goldstein Steven ; Levy Robert J. ; Labhasetwar Vinod ; Bonadio Jeffrey F., Compositions and methods for coating medical devices.
  37. Baird, Andrew; Gonzalez, Ana Maria; Logan, Ann; Berry, Martin, Compositions and methods for delivery of agents for neuronal regeneration and survival.
  38. Shimp, Lawrence A.; Behnam, Keyvan; Wei, Guobao; Selim, Abdulhafez A., Compositions and methods for promoting bone formation.
  39. Chen Charles C. ; Jefferies Steven R., Compositions with enhanced osteogenic potential, methods for making the same and uses thereof.
  40. Brem Henny ; Langer Robert S. ; Domb Abraham J.,ILX, Controlled local delivery of chemotherapeutic agents for treating solid tumors.
  41. Dunn, Richard L.; Yarborough, Cody L., Coupling syringe system and methods for obtaining a mixed composition.
  42. Janski Alvin M. (Terre Haute IN) Yang Ren-Der (Terre Haute IN), Cylindrical implants for the controlled release of growth hormones.
  43. Jefferies Steven R., Delayed drug delivery system.
  44. Laurencin Cato T. (Somerville MA) Lucas Paul A. (Macon GA) Syftestad Glenn T. (Sacramento CA) Domb Abraham (Baltimore MD) Glowacki Julie (Jamaica Plan MA) Langer Robert S. (Newton MA), Delivery system for controlled release of bioactive factors.
  45. Michelson, Gary Karlin, Device and method for locking a screw with a bendable plate portion.
  46. Brekke John H., Device and methods for in vivo culturing of diverse tissue cells.
  47. Brekke John H., Device and methods for in vivo culturing of diverse tissue cells.
  48. Evans, Douglas G.; Goldman, Scott M.; Kronengold, Russell T., Devices and methods for treating defects in the tissue of a living being.
  49. Evans, Douglas G; Goldman, Scott M.; Kronengold, Russell T., Devices and methods for treating defects in the tissue of a living being.
  50. Evans, Douglas G; Goldman, Scott M.; Kronengold, Russell T., Devices and methods for treating defects in the tissue of a living being.
  51. Evans, Douglas G; Goldman, Scott M.; Kronengold, Russell T., Devices and methods for treating defects in the tissue of a living being.
  52. Evans, Douglas G; Goldman, Scott M.; Kronengold, Russell T., Devices and methods for treating defects in the tissue of a living being.
  53. Evans, Douglas G; Goldman, Scott M.; Kronengold, Russell T., Devices and methods for treating defects in the tissue of a living being.
  54. Evans, Douglas G; Goldman, Scott M.; Kronengold, Russell T., Devices and methods for treating defects in the tissue of a living being.
  55. Evans, Douglas G; Goldman, Scott M.; Kronengold, Russell T., Devices and methods for treating defects in the tissue of a living being.
  56. Oppermann Hermann ; Ozkaynak Engin ; Kuberasampath Thangavel ; Rueger David C. ; Pang Roy H. L., Devices comprising chondrogenic protein and methods of inducing endochondral bone formation therewith.
  57. Dunn,Richard L., Emulsions for in-situ delivery systems.
  58. Joseph P. Vacanti ; Christopher K. Breuer ; Beverly E. Chaignaud ; Toshiraru Shin'oka, Engineering of strong, pliable tissues.
  59. Vacanti Joseph P. ; Breuer Christopher K. ; Chaignaud Beverly E. ; Shin'oka Toshiraru, Engineering of strong, pliable tissues.
  60. Vacanti, Joseph P.; Breuer, Christopher K.; Chaignaud, Berverly E.; Shin'oka, Toshiraru, Engineering of strong, pliable tissues.
  61. Vacanti, Joseph P.; Breuer, Christopher K.; Chaignaud, Berverly E.; Shin'oka, Toshiraru, Engineering of strong, pliable tissues.
  62. McKay, William F.; Peckham, Steven M., Flowable carrier compositions and methods of use.
  63. Leonard, Edward F.; Reich, Ilan K.; Cortell, Stanley, Fluid separation devices, systems and methods.
  64. Hubbell Jeffrey A. ; Pathak Chandrashekhar P. ; Sawhney Amarpreet S. ; Desai Neil P. ; Hill Jennifer L. ; Hossainy Syed F. A., Gels for encapsulation of biological materials.
  65. Bonadio Jeffrey ; Goldstein Steven A., Gene transfer into bone cells and tissues.
  66. Morris, John W.; Knaack, David A.; Shimp, Lawrence A.; Behnam, Keyvan; Skinner, Robert P.; Betz, Randal R., Hemostatic bone graft.
  67. Coury Arthur J. (Boston MA) Avila Luis Z. (Arlington MA) Pathak Chandrashekhar P. (Waltham MA) Barman Shikha P. (Lowell MA), Hydroxy-acid cosmetics.
  68. Coury Arthur J. ; Avila Luis Z. ; Pathak Chandrashekhar P. ; Barman Shikha P., Hydroxy-acid cosmetics.
  69. Beyer, Jr., Wayne F.; Hyde-DeRuyscher, Robin; Hamilton, Paul T.; Benson, Ray Edward, IFBM's to promote the specific attachment of target analytes to the surface of orthopedic implants.
  70. Beyer, Jr., Wayne F.; Hyde-DeRuyscher, Robin; Hamilton, Paul T.; Benson, Ray Edward, IFBM's to promote the specific attachment of target analytes to the surface of orthopedic implants.
  71. Beyer, Jr., Wayne F.; Hyde-DeRuyscher, Robin; Hamilton, Paul T.; Benson, Ray Edward, IFBM's to promote the specific attachment of target analytes to the surface of orthopedic implants.
  72. Michelson, Gary K., Implant with openings adapted to receive bone screws.
  73. Michelson, Gary K., Implant with openings adapted to receive bone screws.
  74. Michelson, Gary K., Implant with openings adapted to receive bone screws.
  75. Michelson,Gary K., Implant with trailing end adapted to receive bone screws.
  76. Benedict, James J.; Damien, Christopher J., Implantable putty material.
  77. Hubbell,Jeffrey A.; Pathak,Chandrashekhar P.; Sawhney,Amarpreet S.; Desai,Neil P.; Hill,Jennifer L.; Hossainy,Syed F. A., Implantable substrate coated with a macromer having free radical polymerizable substituents.
  78. Vacanti Joseph P. ; Langer Robert S. ; Johnson Lynt, Implantation of cell-matrix structure adjacent mesentery, omentum or peritoneum tissue.
  79. Goldstein Steven A. ; Bonadio Jeffrey, In vivo gene transfer methods for wound healing.
  80. Michelson, Gary Karlin, Interbody spinal fusion implants.
  81. Michelson, Gary K., Interbody spinal implant with trailing end adapted to receive bone screws.
  82. Peter Alexander Cole ; Douglas Eric Parsell, Intramedullary catheter nail apparatus and method.
  83. Chern, Rey T.; Zingerman, Joel R., Liquid polymeric compositions for controlled release of bioactive substances.
  84. Greer,Keith; King,Richard S., Low crystalline polymeric material for orthopaedic implants and an associated method.
  85. Jensenius, Jens Chr.; Thiel, Steffen, MASP 2, a complement-fixing enzyme, and uses for it.
  86. Jensenius, Jens Chr.; Thiel, Steffen, MASP-2, a complement fixing enzyme, and uses for it.
  87. Gayer Gregory G. ; Comfort Christopher J., Method and apparatus for augmentating osteointegration of prosthetic implant devices.
  88. Gregory G. Gayer ; Christopher J. Comfort, Method and apparatus for augmenting osteointegration of prosthetic implant devices.
  89. Novak, Vincent P.; Ammann, Kelly; McDevitt, Dennis, Method and apparatus for forming a wedge-like opening in a bone for an open wedge osteotomy.
  90. Ammann, Kelly G.; Novak, Vincent P.; Schneider, Robert E.; Taber, Justin R., Method and apparatus for performing a high tibial, dome osteotomy.
  91. Ammann, Kelly; Novak, Vincent P.; Schneider, Robert; Burns, Ralph E.; Amendola, Annunziato, Method and apparatus for performing an open wedge osteotomy.
  92. Ammann, Kelly G.; Novak, Vincent P.; Schneider, Robert E.; Burns, Ralph E., Method and apparatus for performing an open wedge, high tibial osteotomy.
  93. Ammann, Kelly G.; Novak, Vincent P.; Schneider, Robert E.; Burns, Ralph E., Method and apparatus for performing an open wedge, high tibial osteotomy.
  94. Ammann, Kelly G.; Novak, Vincent P.; Schneider, Robert E.; Burns, Ralph E.; Moses, Michael C.; Taber, Justin R., Method and apparatus for performing an open wedge, high tibial osteotomy.
  95. Ammann, Kelly G.; Novak, Vincent P.; Schneider, Robert E.; Taber, Justin R., Method and apparatus for performing an open wedge, high tibial osteotomy.
  96. Ammann, Kelly; Novak, Vincent P.; Schneider, Robert, Method and apparatus for performing an open wedge, high tibial osteotomy.
  97. Ammann, Kelly; Novak, Vincent P.; Schneider, Robert, Method and apparatus for performing an open wedge, high tibial osteotomy.
  98. Ammann, Kelly; Novak, Vincent P.; Schneider, Robert; Burns, Ralph E., Method and apparatus for performing an open wedge, high tibial osteotomy.
  99. Ammann, Kelly; Novak, Vincent P.; Schneider, Robert; Burns, Ralph E., Method and apparatus for performing an open wedge, high tibial osteotomy.
  100. Novak, Vincent P.; Ammann, Kelly G.; Schneider, Robert E., Method and apparatus for performing an open wedge, high tibial osteotomy.
  101. Philippon, Marc J.; Ammann, Kelly; Egan, J. Michael; Rindal, Bjorn N., Method and apparatus for performing an osteotomy in bone.
  102. Polson Alan M. ; Swanbom Deryl D. ; Dunn Richard L. ; Cox Charles P. ; Norton Richard L. ; Lowe Bryan K. ; Peterson Kenneth S., Method and composition for treating a bone tissue defect.
  103. Anderson Mark E. (21 Southampton Ct. Newport Beach CA 92660), Method for administering interleukin-2.
  104. Hippensteel, Gregory M.; Peek, Lawrence F.; Anderson, Jeffrey P.; Gorhe, Devendra; Allen, Steve M., Method for bonding a tantalum structure to a cobalt-alloy substrate.
  105. Hippensteel, Gregory M.; Peek, Lawrence F.; Anderson, Jeffrey P.; Gorhe, Devendra; Allen, Steve M.; Scrafton, Joel G.; Harmon, Casey, Method for bonding a tantalum structure to a cobalt-alloy substrate.
  106. Bradford David S., Method for effecting bone repair.
  107. Anderson H. Clarke, Method for inducing bone formation using an extract of human osteosarcoma cell line SAOS-2.
  108. Anderson H. Clarke ; Hsu Howard H. T., Method for inducing bone formation using an extract of human osteosarcoma cell line SAOS-2.
  109. Poddevin Nicolas,FRX ; Fages Jacques,FRX ; Guidoin Robert,FRX, Method for manufacturing and treating textiles.
  110. Fox ; Jr. Charles L. (Fort Lauderdale FL) Modak Shanta M. (River Edge NJ), Method for preparing infection-resistant materials.
  111. Baumgartner, Ludwig, Method for producing a bone material enriched with bone growth factors.
  112. Jennissen, Herbert; Chatzinikolaidou, Maria, Method for producing a product having a polymer matrix, implants made thereof and use thereof.
  113. Dalal, Paresh S.; Diamaano, Godofredo R.; Kulkarni, Shailesh C., Method for producing porous β-tricalcium phosphate granules.
  114. Oppermann Hermann (Medway MA) Kuberasampath Thangavel (Medway MA) Rueger David C. (West Roxbury MA) Ozkaynak Engin (Milford MA), Method for recombinant production of osteogenic protein.
  115. Dalal,Paresh S; Dimaano,Godofredo R; Toth,Carol A; Kulkarni,Shailesh C, Method of delivering a bioactive agent with porous β-tricalcium phosphate granules.
  116. Mikos, Antonios G.; Langer, Robert S.; Vacanti, Joseph P.; Griffith, Linda G.; Sarakinos, Georgios, Method of forming a tissue structure by introducing cells into an implanted matrix.
  117. Dalal,Paresh S; Dimaano,Godofredo R; Toth,Carol A; Kulkarni,Shailesh C, Method of forming bone with porous βtricalcium phosphate granules.
  118. Agrawal C. Mauli ; Schenck Robert C., Method of making a porous prothesis with biodegradable coatings.
  119. Smith, Todd S.; Hanes, Mark D.; King, Richard, Method of making an implantable orthopaedic bearing.
  120. Morris, John W.; Shimp, Lawrence A.; Petersen, Kenneth C.; Manrique, Albert; Kaes, David; Scarborough, Nelson; Dowd, Michael, Method of making demineralized bone particles.
  121. Morris, John W.; Shimp, Lawrence A.; Petersen, Kenneth C.; Manrique, Albert; Kaes, David; Scarborough, Nelson; Dowd, Michael, Method of making demineralized bone particles.
  122. Oppermann, Hermann; Ozkaynak, Engin; Kuberasampath, Thangavel; Rueger, David C.; Pang, Roy H. L., Method of using recombinant osteogenic protein to repair bone or cartilage defects.
  123. Bonadio Jeffrey ; Goldstein Steven A., Methods and compositions for multiple gene transfer into bone cells.
  124. Ashkar Samy ; Atala Anthony, Methods and compositions for programming an organic matrix for remodeling into a target tissue.
  125. Gruskin, Elliott A.; Buechter, Douglas D.; Zhang, Guanghui; Connelly, Kevin, Methods for producing extracellular matrix proteins.
  126. Demopulos, Gregory A.; Dudler, Thomas; Schwaeble, Hans-Wilhelm, Methods for treating conditions associated with MASP-2 dependent complement activation.
  127. Demopulos, Gregory A.; Dudler, Thomas; Schwaeble, Hans-Wilhelm, Methods for treating conditions associated with MASP-2 dependent complement activation.
  128. Demopulos, Gregory A.; Dudler, Thomas; Schwaeble, Hans-Wilhelm, Methods for treating conditions associated with MASP-2 dependent complement activation.
  129. Demopulos, Gregory A.; Dudler, Thomas; Schwaeble, Hans-Wilhelm, Methods for treating conditions associated with MASP-2 dependent complement activation.
  130. Schwaeble, Hans-Wilhelm; Tedford, Clark E.; Parent, James B.; Dudler, Thomas; Demopulos, Gregory A., Methods for treating conditions associated with MASP-2 dependent complement activation.
  131. Rutherford,Bruce; Somogyi,Christopher; White,Clinton; Rabins,Erick, Methods for treating dental conditions using tissue scaffolds.
  132. Schwaeble, Hans-Wilhelm; Dudler, Thomas; Tedford, Clark E.; Parent, James B.; Demopulos, Gregory A., Methods for treating disseminated intravascular coagulation by inhibiting MASP-2 dependent complement activation.
  133. Leonard, Edward F.; West, Alan C.; Shapley, Nina C.; Tang, Zhongliang, Methods of blood-based therapies having a microfluidic membraneless exchange device.
  134. Sailer,Hermann; Weber,Franz, Methods of inhibiting or inducing bone formation.
  135. Bonadio, Jeffrey; Yin, Wushan, Methods of using latent TGF-β binding proteins.
  136. Novak, Vincent P.; Ammann, Kelly, Multi-part implant for open wedge knee osteotomies.
  137. Oppermann,Hermann; Kuberasampath,Thangavel; Rueger,David C.; Ozkaynak,Engin, Nucleic acid molecules encoding osteogenic proteins.
  138. Elliott A. Gruskin ; Douglas D. Buechter ; Guanghui Zhang ; Kevin Connelly, Nucleic acids encoding extracellular matrix proteins.
  139. Oppermann Hermann ; Ozkaynak Engin ; Kuberasampath Thangavel ; Rueger David C. ; Pang Roy H. L., Nucleic acids encoding osteogenic proteins.
  140. Oppermann Hermann ; Kuberasampath Thangavel ; Rueger David C. ; Ozkaynak Engin, Nucleotide sequences encoding osteogenic proteins.
  141. Scaffidi, James, Nutritional supplement and use thereof.
  142. Garigapati, Venkat R.; TenHuisen, Kevor S., Organophosphorous and multivalent metal compound compositions and methods.
  143. Garigapati, Venkat R.; Hess, Brian J.; Kimsey, Cassandra L.; Murphy, Matthew E., Organophosphorous, multivalent metal compounds, and polymer adhesive interpenetrating network compositions and methods.
  144. Smith, Todd S.; Hanes, Mark D.; King, Richard, Orthopaedic bearing and method for making the same.
  145. Smith, Todd S.; Hanes, Mark D.; King, Richard, Orthopaedic bearing and method for making the same.
  146. Michelson, Gary K., Orthopedic implant with locking element.
  147. Michelson, Gary K., Orthopedic implant with locking element.
  148. Michelson, Gary K., Orthopedic implant with locking element.
  149. Oppermann Hermann (Medway MA) Kuberasampath Thangavel (Medway MA) Rueger David C. (West Roxbury MA) Ozkaynak Engin (Milford MA), Osteogenic devices.
  150. Oppermann Hermann (Medway MA) Ozkaynak Engin (Milford MA) Kuberasampath Thangavel (Medway MA) Rueger David C. (Hopkinton MA) Pang Roy H. L. (Medway MA), Osteogenic devices.
  151. Oppermann Hermann ; Kuberasampath Thangavel ; Rueger David C. ; Ozkaynak Engin, Osteogenic devices.
  152. Oppermann, Hermann; Ozkaynak, Engin; Kuberasampath, Thangavel; Rueger, David C.; Pang, Roy H. L., Osteogenic devices.
  153. Oppermann, Hermann; Ozkaynak, Engin; Kuberasampath, Thangavel; Rueger, David C.; Pang, Roy H. L., Osteogenic devices.
  154. Ogawa, Takahiro; Jewett, Anahid, Osteogenic enhancer composition.
  155. Oppermann,Hermann; Ozkaynak,Engin; Kuberasampath,Thangavel; Rueger,David C.; Pang,Roy H. L., Osteogenic proteins.
  156. Kuberasampath Thangavel (Medway MA) Rueger David C. (West Roxbury MA), Osteogenic proteins and polypeptides.
  157. Manrique, Albert; Edwards, Jean T.; Scarborough, Nelson L.; Boden, Scott D.; Traianedes, Kathy; Shimp, Lawrence A.; Russell, James L., Osteoimplant and method of making same.
  158. Manrique, Albert; Edwards, Jean T.; Scarborough, Nelson L.; Boden, Scott D.; Traianedes, Kathy; Shimp, Lawrence A.; Russell, James L., Osteoimplant and method of making same.
  159. Manrique, Albert; Edwards, Jean T.; Scarborough, Nelson L.; Boden, Scott D.; Traianedes, Kathy; Shimp, Lawrence A.; Russell, James L., Osteoimplant and method of making same.
  160. Betz, Randal R.; Boden, Scott D.; Clark, Christine; Forsyth, Nanette; Morris, John W.; Traianedes, Kathy, Osteoimplants and methods for their manufacture.
  161. Betz, Randal R.; Boden, Scott D.; Clark, Christine; Forsyth, Nanette; Morris, John W.; Traianedes, Kathy, Osteoimplants and methods for their manufacture.
  162. Johnson, James R., Packable ceramic beads for bone repair.
  163. Johnson, James R., Packable ceramic beads for bone repair.
  164. Agrawal C. Mauli ; Athanasiou Kyriacos A., Permeable compositions and methods for their preparation.
  165. Sailer,Hermann; Weber,Franz, Pharmaceutical compositions comprising bone morphogenetic protein monomers for inhibiting bone formation.
  166. Ron Eyal (Lexington MA) Turek Thomas J. (Boston MA) Isaacs Benjamin S. (Tewksbury MA) Patel Himakshi (Tewksbury MA) Kenley Richard A. (Andover MA), Pharmaceutical formulations of osteogenic proteins.
  167. Hubbell Jeffrey A. (Austin TX) Pathak Chandrashekhar P. (Waltham MA) Sawhney Amarpreet S. (Newton MA) Desai Neil P. (Los Angeles CA) Hill Jennifer L. (Austin TX), Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers.
  168. Hubbell Jeffrey A. ; Pathak Chandrashekhar P. ; Sawhney Amarpreet S. ; Desai Neil P. ; Hill Jennifer L., Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers.
  169. Hubbell Jeffrey A. ; Pathak Chandrashekhar P. ; Sawhney Amarpreet S. ; Desai Neil P. ; Hill-West Jennifer L., Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers.
  170. Hubbell, Jeffrey A.; Pathak, Chandrashekhar P.; Sawhney, Amarpreet S.; Desai, Neil P.; Hill, Jennifer L., Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers.
  171. Michelson, Gary K., Plating system having retaining member that permits movement of at least one bone fastener.
  172. Coury Arthur J. ; Avila Luis Z. ; Pathak Chandrashekhar P. ; Barman Shikha P., Poly(hydroxy acid)/polymer conjugates for skin applications.
  173. Mikos, Antonios G.; Langer, Robert S.; Vacanti, Joseph P.; Griffith, Linda G.; Sarakinos, Georgios, Porous biodegradable polymeric materials for cell transplantation.
  174. Mikos,Antonios G.; Vacanti,Joseph P.; Langer,Robert S.; Griffith,Linda G.; Sarakinos,Georgios, Porous biodegradable polymeric materials for cell transplantation.
  175. Agrawal C. Mauli ; Schenck Robert C., Porous prosthesis with biodegradable material impregnated intersticial spaces.
  176. Dalal, Paresh S.; Dimaano, Godofredo R.; Toth, Carol Ann; Kulkarni, Shailesh C., Porous β-tricalcium phosphate granules for regeneration of bone tissue.
  177. Ringeisen Timothy ; Brekke John H., Process and device for treating and healing a tissue deficiency.
  178. Anderson, Jeffrey P.; Popoola, Oludele, Process for forming a ceramic layer.
  179. Anderson, Jeffrey P.; Popoola, Oludele O., Process for forming a ceramic layer.
  180. Tunc, Deger C.; Ranawat, Chitranjan S.; Ranawat, Amar S., Prosthesis with sustained release analgesic.
  181. Bonadio Jeffrey ; Yin Wushan, Recombinant production of latent TGF-beta binding protein-3 (LTBP-3).
  182. Coombes Allan G. A. (San Antonio TX) Heckman James D. (San Antonio TX) Boyan Barbara D. (San Antonio TX), Resorbable materials based on independently gelling polymers of a single enantiomeric lactide.
  183. McKay, William F., Rigid bone graft substitute.
  184. Michelson, Gary K., Segmentable plate with locking element.
  185. Michelson, Gary K., Single-lock plating system.
  186. Zhang, Kai; Buehler, Daniel; Brinkerhuff, Hallie E.; Hawkins, Michael E.; Klabunde, Ralf, Spacer with a coating thereon for use with an implant device.
  187. Gary Karlin Michelson, Spinal implant with bone screws.
  188. Carney, Darrell H.; Crowther, Roger S.; Simmons, David J.; Yang, Jinping; Redin, William R., Stimulation of bone growth with thrombin peptide derivatives.
  189. Kuberasampath, Thangavel; Tarrant, Lawrence Berlowitz, Synthetic bone matrix.
  190. Thangavel Kuberasampath ; Lawrence Berlowitz Tarrant, Synthetic bone matrix.
  191. Evans, Douglas G., System and devices for the repair of a vertebral disc defect.
  192. Evans, Douglas G., System and devices for the repair of a vertebral disc defect.
  193. Evans, Douglas G.; Bradica, Gino; Kelly, Jeffrey C.; Carouge, Michael K., System and devices for the repair of a vertebral disc defect.
  194. Evans, Douglas G.; Kelly, Jeffrey C.; Bradica, Gino; Carouge, Michael K.; Oeffinger, Brian, System and devices for the repair of a vertebral disc defect.
  195. Evans, Douglas G.; Kelly, Jeffrey C.; Bradica, Gino; Carouge, Michael K.; Oeffinger, Brian, System and devices for the repair of a vertebral disc defect.
  196. Michelson, Gary K., System and method for stabilizing a portion of the spine.
  197. Leonard, Edward F.; West, Alan C.; Shapley, Nina C.; Tang, Zhongliang, Systems and methods for membraneless dialysis.
  198. Leonard, Edward F.; West, Alan C.; Shaplely, Nina C.; Tang, Zhongliang, Systems and methods of blood-based therapies having a microfluidic membraneless exchange device.
  199. Leonard, Edward F.; West, Alan C.; Shapley, Nina C.; Tang, Zhongliang, Systems and methods of blood-based therapies having a microfluidic membraneless exchange device.
  200. Leonard, Edward F.; West, Alan C.; Aucoin, Christian P.; Nanne, Edgar E., Systems and methods of microfluidic membraneless exchange using filtration of extraction outlet streams.
  201. Leonard, Edward F.; West, Alan C.; Aucoin, Christian Paul; Nanne, Edgar E., Systems and methods of microfluidic membraneless exchange using filtration of extraction outlet streams.
  202. Leonard, Edward F.; West, Alan C.; Aucoin, Christian Paul; Nanne, Edgar E., Systems and methods of microfluidic membraneless exchange using filtration of extraction outlet streams.
  203. Leonard, Edward F.; West, Alan C.; Aucoin, Christian Paul; Nanne, Edgar E., Systems and methods of microfluidic membraneless exchange using filtration of extraction outlet streams.
  204. Leonard, Edward F.; West, Alan C.; Aucoin, Christian Paul; Nanne, Edgar E., Systems and methods of microfluidic membraneless exchange using filtration of extraction outlet streams.
  205. Leonard, Edward F.; West, Alan C.; Aucoin, Christian Paul; Nanne, Edgar E., Systems and methods of microfluidic membraneless exchange using filtration of extraction outlet streams.
  206. Stone Roger Lee (Hamilton OH), Therapeutic compositions for osteoinduction.
  207. Michelson, Gary K., Threadless multi-lock anterior cervical plating system.
  208. Vacanti Joseph P. ; Langer Robert S., Three-dimensional fibrous scaffold containing attached cells for producing vascularized tissue in vivo.
  209. Jeffrey A. Hubbell CH; Chandrashekhar P. Pathak ; Amarpreet Sawhney ; Neil Desai ; Syed Hossainy ; Jennifer L. Hill-West, Treating medical conditions by polymerizing macromers to form polymeric materials.
  210. Agrawal C. Mauli ; Athanasiou Kyriacos A., Variable permeability bone implants, methods for their preparation and use.
  211. Scarborough, Nelson L.; Gadaleta, Sergio J.; Keas, David; Manrique, Albert, Volume maintaining osteoinductive/osteoconductive compositions.
  212. Scarborough, Nelson L.; Gadeleta, Sergio J.; Kaes, David R.; Manrique, Albert, Volume maintaining osteoinductive/osteoconductive compositions.
  213. Fuller, Shawn; Claseman, Bryan A.; Slager, Joram; Missling, Jeffrey J.; Maharaj, Gary; Opperman, Gary W.; Lockwood, Nathan A.; Hergenrother, Robert W.; Olson, Charles, Wound packing device and method.
  214. Fuller, Shawn; Claseman, Bryan A.; Slager, Joram; Missling, Jeffrey J.; Maharaj, Gary; Opperman, Gary W.; Lockwood, Nathan; Hergenrother, Robert W.; Olson, Charles, Wound packing device and methods.
  215. Maharaj, Gary; Woodwick Sides, Teryl L., Wound packing device with nanotextured surface.
  216. McDonnell, Christopher, Woven retention devices, systems and methods.
  217. McDonnell, Christopher, Woven retention devices, systems and methods.
  218. McDonnell, Christopher; Richards, Robert L.; Sroka, Nicole S.; Corrao, Jr., Ernest N.; Litke, Jr., Ronald G., Woven retention devices, systems, packaging, and related methods.
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로