초록 ▼

Described is a directly compressible formulation comprising calcium carbonate, citric acid, and a compression vehicle. In the preferred embodiment, the compression vehicle comprises a maltodextrin and lactose. The formulation can be compressed into an effervescent tablet system, which when placed in

Described is a directly compressible formulation comprising calcium carbonate, citric acid, and a compression vehicle. In the preferred embodiment, the compression vehicle comprises a maltodextrin and lactose. The formulation can be compressed into an effervescent tablet system, which when placed in water effervesces in a relatively rapid dissolution releasing CO2 and resulting in a solution of monocalcium citrate.

대표청구항 ▼

A directly compressed substantially stable effervescent tablet calcium composition comprising approximately 7.5% to approximately 87.5% by weight calcium carbonate having an average particle diameter under approximately 400 microns, approximately 10% to approximately 90% by weight uncoated organic a

A directly compressed substantially stable effervescent tablet calcium composition comprising approximately 7.5% to approximately 87.5% by weight calcium carbonate having an average particle diameter under approximately 400 microns, approximately 10% to approximately 90% by weight uncoated organic acid component having a relatively larger average diameter than that of the calcium carbonate, and approximately 2.5% to approximatley 18.5% by weight of a compression enhancing vehicle which is maltodextrin, a disaccharide sugar, or a mixture thereof, based on the combined weight of these three components, with the organic acid component being at least 80% by weight citric acid, and wherein the compression vehicle is coated on the calcium carbonate.