초록 ▼

An indicator for detecting residual ethylene oxide comprising a substrate impregnated with a solution of 4-(4-nitrobenzyl)pyridine and an envelope of the substrate which is at least partially transparent and has low permeability to gaseous ethylene oxide is provided, the envelope being preferably ma

An indicator for detecting residual ethylene oxide comprising a substrate impregnated with a solution of 4-(4-nitrobenzyl)pyridine and an envelope of the substrate which is at least partially transparent and has low permeability to gaseous ethylene oxide is provided, the envelope being preferably made of a transparent plastic film. With the indicator, an amount of ethylene oxide remaining in various medical instruments, etc. may be estimated by the naked eye since the color of the indicator changes step by step in the course of the release of residual ethylene oxide.

대표청구항 ▼

An indicator for estimating concentrations of ethylene oxide remaining in medical instruments or sanitary goods during or after aeration following sterilization of said instruments or goods with ethylene oxide comprising: (a) a substrate formed by impregnating a paper body with a solution consisting

An indicator for estimating concentrations of ethylene oxide remaining in medical instruments or sanitary goods during or after aeration following sterilization of said instruments or goods with ethylene oxide comprising: (a) a substrate formed by impregnating a paper body with a solution consisting of about 0.5-5% by weight of 4-(4- nitrobenzyl)-pyridine in an organic solvent and removing said solvent; and (b) an envelope enclosing said substrate, said envelope comprising a transparent, heat-sealable single layer or composite plastic film having a low permeability to ethylene oxide and a permeability to carbon dioxide of not more than about 200 ml/100 in 2/mil/24 hours at 25°C. under 1 atmosphere and at 50% relative humidity, said substrate sequentially changing color step-wise following the exposure of the indicator to ethylene oxide gas, with the color change of said substrate during the aeration being controlled by said envelope having a low permeability to ethylene oxide.