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Process for sex determination in man by use of monoclonal antibodies to the H-Y antigen 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • G01N-033/577
  • C12N-005/00
  • C12P-015/00
  • A61K-039/395
출원번호 US-0521635 (1983-08-09)
발명자 / 주소
  • Hammerling Ulrich (New York NY) Koo Gloria C. (Woodbridge NJ) Tada Nobuhiko (New York NY)
출원인 / 주소
  • Sloan-Kettering Institute for Cancer Research (New York NY 02)
인용정보 피인용 횟수 : 47  인용 특허 : 5

초록

Production of anti-H-Y hybridoma cell lines, and the use of the antibodies to determine the presence of H-Y antigen to indicate the sex of the proband inclusive of fetus, newborn and adult humans.

대표청구항

Hybridoma cell lines selected from the group consisting of ATCC HB 9070, ATCC HB 9071 and ATCC HB 9072 producing monoclonal antibodies 12/44, 12/49, and 11/6 which specifically bind to the H-Y antigen.

이 특허에 인용된 특허 (5)

  1. Goldberg Ellen H. (Albuquerque NM), ATCC HB8116 And its monoclonal anti-H-Y antibody, Hyclonalan.
    상세보기
  2. David Gary S. (La Jolla CA) Greene Howard E. (Carlsbad CA), Immunometric assays using monoclonal antibodies.
    상세보기
  3. Bryant Bernard J. (509 Scripps Dr. Davis CA 95616), Method and material for increasing the percentage of mammalian offspring of either sex.
    상세보기
  4. Koprowski Hilary (Wynnewood PA) Croce Carlo M. (Philadelphia PA), Method of producing tumor antibodies.
    상세보기
  5. Davis ; Raymond Vincent, Radioimmunoassay.
    상세보기

이 특허를 인용한 특허 (47)

  1. Durack, Gary; Wallace, Jeffrey D.; Vandre, Gary P.; Westfall, Lon A.; Hatcher, Jeremy T.; Nayak, Niraj V., Apparatus, methods and processes for sorting particles and for providing sex-sorted animal sperm.
    상세보기
  2. Evans, Kenneth M.; Gilligan, Thomas B., Apparatus, methods and processes for sorting particles and for providing sex-sorted animal sperm.
    상세보기
  3. Sullivan, Brian M.; Zsolnay, Denes L., Automated enzyme-linked immunosorbent assay device with ONP-GP.
    상세보기
  4. Seidel,George E.; Herickhoff,Lisa; Schenk,John L., Collection systems for cytometer sorting of sperm.
    상세보기
  5. Durack, Gary; Wallace, Jeffrey D.; Vandre, Gary P.; Westfall, Lon A.; Hatcher, Jeremy T.; Nayak, Niraj V., Flow cytometer apparatus and method.
    상세보기
  6. Durack, Gary; Wallace, Jeffrey D.; Vandre, Gary P.; Westfall, Lon A.; Hatcher, Jeremy T.; Nayak, Niraj V., Flow cytometer method and apparatus.
    상세보기
  7. Didion, Bradley; Erwin, Whitney; Bleher, Reiner, Gender-specific separation of sperm cells and embryos.
    상세보기
  8. Schenk, John L.; Seidel, George E.; Suh, Tae Kwang; Moreno, Juan F.; Rosenstein, Maurice A., Heterogeneous inseminate system.
    상세보기
  9. Evans,Kenneth M.; van Munster,Erik B., High purity X-chromosome bearing and Y-chromosome bearing populations of spermatozoa.
    상세보기
  10. Evans, Kenneth M., High resolution flow cytometer.
    상세보기
  11. Seidel, George E.; Lu, Kehuan; Suh, Tae Kwang, In-vitro fertilization systems with spermatozoa separated into X-chromosome and Y-chromosome bearing populations.
    상세보기
  12. Schenk, John L.; Seidel, George E.; Suh, Tae Kwang, Low pressure sperm cell separation system.
    상세보기
  13. Durack, Gary; Wallace, Jeffrey D.; Vandre, Gary P.; Westfall, Lon A.; Hatcher, Jeremy T.; Nayak, Niraj V., Method and apparatus for calibrating a flow cytometer.
    상세보기
  14. Tse Doris B. ; Chung Hui-Min ; Van der Ploeg Leonardus H. T., Method for preserving cells, and uses of said method.
    상세보기
  15. Evans, Kenneth M.; van Munster, Erik B., Method for producing high purity X-chromosome bearing and Y-chromosome bearing populations of spermatozoa.
    상세보기
  16. Benjamin Thomas L. ; Kohn Barbara ; Basker Christopher J. ; George Susan ; Livingston David, Method for sex determination of mammalian offspring.
    상세보기
  17. Thomas L. Benjamin ; Barbara Kohn ; Christopher J. Basker ; Susan George ; David Livingston, Method for sex determination of mammalian offspring.
    상세보기
  18. Zavos Panayiotis M. (Lexington KY) Dawson Karl A. (Lexington KY), Method for x and y spermatozoa separation.
    상세보기
  19. Schenk, John L., Method of cryopreserving selected sperm cells.
    상세보기
  20. Schenk,John L., Method of cryopreserving selected sperm cells.
    상세보기
  21. Squires, Edward L.; McCue, Patrick M.; Seidel, George E., Method of establishing an equine artificial insemination sample.
    상세보기
  22. Seidel, George E.; Suh, Tae Kwang; Lu, Kehuan, Method of in-vitro fertilization with spermatozoa separated into X-chromosome and Y-chromosome bearing populations.
    상세보기
  23. Evans, Kenneth M.; van Munster, Erik B., Methods and apparatus for high purity X-chromosome bearing and Y-chromosome bearing populations of spermatozoa.
    상세보기
  24. Schenk, John L., Methods and apparatus for reducing protein content in sperm cell extenders.
    상세보기
  25. Seidel, George; Herickhoff, Lisa; Schenk, John, Methods for improving sheath fluids and collection systems for sex-specific cytometer sorting of sperm.
    상세보기
  26. Seidel, George E.; Suh, Tae Kwang; Lu, Kehuan; Cran, David G., Methods for separating frozen-thawed spermatozoa into X-chromosome bearing and Y-chromosome bearing populations.
    상세보기
  27. Durack, Gary; Wallace, Jeffrey D.; Vandre, Gary P.; Westfall, Lon A.; Hatcher, Jeremy T.; Nayak, Niraj V., Multi-channel system and methods for sorting particles.
    상세보기
  28. Durack, Gary; Wallace, Jeffrey D.; Vandre, Gary P.; Westfall, Lon A.; Hatcher, Jeremy T.; Nayak, Niraj V., Multi-channel system and methods for sorting particles.
    상세보기
  29. Seidel, George; Herickhoff, Lisa; Schenk, John, Multiple sexed embryo production system for bovine mammals.
    상세보기
  30. George Seidel ; Lisa Herickhoff ; John Schenk, Multiple sexed embryo production system for mammals.
    상세보기
  31. Sharpe, Jonathan C.; Schaare, Peter N., Optical apparatus.
    상세보기
  32. Sharpe,Jonathan C.; Schaare,Peter N., Optical apparatus.
    상세보기
  33. Graham, Jeffrey A., Process for enriching a population of sperm cells.
    상세보기
  34. Durak, Gary; Wallace, Jeffrey D.; Vandre, Gary P.; Westfall, Lon A.; Hatcher, Jeremy T.; Nayak, Niraj V., Process for evaluating staining conditions of cells for sorting.
    상세보기
  35. Copperman, Alan; Grunfeld, Lawrence; Mukherjee, Tanmoy; Sandler, Benjamin, Protocol for detecting proteins in a culture containing an embryo.
    상세보기
  36. Seidel, George E.; Lu, Kehuan; Suh, Tae Kwang; Cran, David G., Separation systems of frozen-thawed spermatozoa into X-chromosome bearing and Y-chromosome bearing populations.
    상세보기
  37. Schenk, John L.; Seidel, George E.; Suh, Tae Kwang, Sex selected equine embryo production system.
    상세보기
  38. Spaulding Glenn F. (Phoenix AZ), Sex-associated membrane antibodies and their use for increasing the probability that offspring will be of a desired sex.
    상세보기
  39. Seidel George ; Herickhoff Lisa ; Schenk John, Sheath fluids and collection systems for sex-specific cytometer sorting of sperm.
    상세보기
  40. Maxwell,William Maxwell Chisholm; Hollinshead,Fiona Kate; O'Brien,Justine Kellie; Evans,Gareth, Sperm cell processing and preservation systems.
    상세보기
  41. Ludwig, Cindy L.; Crowley, Kathleen S.; Graves, Charles N., Sperm suspensions for sorting into X or Y chromosome-bearing enriched populations.
    상세보기
  42. Seidel, George E.; Herickhoff, Lisa A.; Schenk, John L., System and method for sorting cells.
    상세보기
  43. Seidel, George E.; Herickhoff, Lisa A.; Schenk, John L., System and method for sorting cells.
    상세보기
  44. Durack, Gary; Wallace, Jeffrey D.; Vandre, Gary P.; Westfall, Lon A.; Hatcher, Jeremy T.; Nayak, Niraj V., System for analyzing particles using multiple flow cytometry units.
    상세보기
  45. Seidel,George E.; Suh,Tae Kwang; Lu,Kehuan, System for in-vitro fertilization with spermatozoa separated into X-chromosome and Y-chromosome bearing populations.
    상세보기
  46. Seidel, George E.; Lu, Kehuan; Suh, Tae Kwang; Cran, David G., System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations.
    상세보기
  47. Durack, Gary; Wallace, Jeffrey D.; Vandre, Gary P.; Westfall, Lon A.; Hatcher, Jeremy T.; Nayak, Niraj V., Systems and methods for sorting particles.
    상세보기

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