초록 ▼

A method and apparatus for non-invasive in vivo inspection of ocular tissue wherein a laser provides a low power, coherent and uniform output beam of light which is guided through the optical system of a modified slit lamp biomicroscope to the eye of a patient for scattering by protein molecules in

A method and apparatus for non-invasive in vivo inspection of ocular tissue wherein a laser provides a low power, coherent and uniform output beam of light which is guided through the optical system of a modified slit lamp biomicroscope to the eye of a patient for scattering by protein molecules in the ocular tissue of the patient, and scattered laser light in the ocular tissue is viewed through the slit lamp to visually align a pick up associated with the slit lamp optical system to a desired location in the ocular tissue. A measurement is performed by receiving laser light scattered from the ocular tissue and converting the scattered light into an electrical signal, and the electrical signal is analyzed by sorting it into components each characterized by an intensity and a fluctuation rate and each component associated with a protein group in the ocular tissue.

대표청구항 ▼

Apparatus for in vivo inspection of ocular tissue comprising: (a) a slit lamp biomicroscope including an illumination optical system comprising a light source, means defining a slit of light and means for imaging the slit of light into the eye of a patient and including a viewing optical system obse

Apparatus for in vivo inspection of ocular tissue comprising: (a) a slit lamp biomicroscope including an illumination optical system comprising a light source, means defining a slit of light and means for imaging the slit of light into the eye of a patient and including a viewing optical system observing light reflected from the eye illuminated by said slit of light; (b) a laser for providing a low power, coherent and uniform output beam of light; (c) means for introducing said laser output light beam to said illumination optical system of said slit lamp in a manner such that said laser light beam is guided to the patient\s eye in a direction of said slit of light; (d) means operatively associated with said viewing optical system of said slit lamp for receiving scattered laser light from the patient\s eye; (e) means for converting the scattered laser light into an electrical signal; and (f) signal processing means for measuring time dependent fluctuations in said signal and sorting said signal into components each characterized by an intensity and a fluctuation rate.