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Iontophoresis apparatus and methods of producing same 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61N-001/00
  • A61N-001/30
출원번호 US-0665698 (1984-10-29)
발명자 / 주소
  • Phipps Joseph B. (Plymouth MN) Untereker Darrel F. (Cedar MN)
출원인 / 주소
  • Medtronic, Inc. (Minneapolis MN 02)
인용정보 피인용 횟수 : 52  인용 특허 : 0

초록

Improved iontophoresis drug delivery apparatus or device wherein one or more electrochemically active components are employed or “sacrificed”so as to minimize the hydrolysis of water during drug delivery. Efficiency of drug delivery is increased and pH changes in the device or adjacent the patient\s

대표청구항

An improved electrode for an iontophoresis device, the electrode comprising: a source of drug to be iontophoretically delivered; support means for said drug source; at least one electrochemically active component in electrical connection to said drug source which, during iontophoretic drug delivery,

이 특허를 인용한 특허 (52)

  1. Yanaki, Jamal S., Active electrode for transdermal medicament administration.
  2. Yanaki, Jamal S., Active transdermal medicament patch and circuit board for same.
  3. Pesach, Benny; Bitton, Gabriel; Nagar, Ron; Weiss, Ram, Device and method for drug delivery.
  4. Pesach, Benny; Bitton, Gabriel; Nagar, Ron; Weiss, Ram, Device and method for drug delivery.
  5. Anderson, Carter R.; Morris, Russell L., Dosage control electrode for iontophoresis device.
  6. Anderson,Carter R.; Morris,Russell L., Dosage control electrode for iontophoresis device.
  7. Pesach, Benny; Bitton, Gabriel; Weiss, Ram; Nagar, Ron, Drug delivery device.
  8. Pesach, Benny; Bitton, Gabriel; Nagar, Ron; Weiss, Ram, Drug delivery device with sensor for closed-loop operation.
  9. Heil, Jr., Ronald W., Electrically controllable, non-occluding, body implantable drug delivery system.
  10. Scott Erik R., Electrotransport device electrode assembly having lower initial resistance.
  11. Phipps J. Bradley ; Moodie Lyn C. ; Gyory J. Richard ; Theeuwes Felix, Electrotransport system with ion exchange material competitive ion capture.
  12. Phipps J. Bradley ; Moodie Lyn C. ; Gyory J. Richard ; Theeuwes Felix, Electrotransport system with ion exchange material providing enhanced drug delivery.
  13. Jacobsen Stephen C. (274 S. 1220 East Salt Lake City UT 84102) Petelenz Tomasz J. (623 University Village UT 84108) Stephen Robert L. (2501 Kensington Ave. Salt Lake City UT 84108), Flow-through methods and apparatus for iontophoresis application of medicaments at a controlled pH.
  14. Akiyama, Hidero; Nakayama, Mizuo; Matsumura, Takehiko; Matsumura, Akihiko, Iontophoresis device.
  15. Kanamura, Kiyoshi; Kosiba, Nobuharu; Nakayama, Mizuo; Matsumura, Takehiko; Akiyama, Hidero; Matsumura, Akihiko, Iontophoresis device.
  16. Kanamura, Kiyoshi; Matsumura, Takehiko; Nakayama, Mizuo; Akiyama, Hidero; Matsumura, Akihiko, Iontophoresis device.
  17. Matsumura,Akihiko; Matsumura,Takehiko; Nakayama,Mizuo; Akiyama,Hidero; Shibata,Tsutomu; Tanioka,Akihiko, Iontophoresis device.
  18. Matsumura,Akihiko; Torisawa,Sakae; Kanamura,Kiyoshi; Ito,Yoshihiro; Kobayashi,Yoriko, Iontophoresis device.
  19. Tanioka, Akihiko; Matsumura, Akihiko; Matsumura, Takehiko; Nakayama, Mizuo; Akiyama, Hidero, Iontophoresis device.
  20. Tanioka, Akihiko; Minagawa, Mie; Kanamura, Kiyoshi; Matsumura, Akihiko; Nakayama, Mizuo; Matsumura, Takehiko; Akiyama, Hidero, Iontophoresis device.
  21. Muller, Daniel; Simonin, Jean-Pierre, Iontophoresis device for transcutaneous administration of a given total quantity of an active principle to a subject.
  22. Atanasoska Ljiljana, Iontophoresis electrode.
  23. Myers Robert M. (Stanford CA) Landrau Felix A. (San Jose CA), Iontophoretic delivery device with single lamina electrode.
  24. Sage Burton H. ; Bock Carl Randolph ; Green Philip G., Iontophoretic delivery of cell adhesion inhibitors.
  25. Sage Burton H. ; Bock Carl Randolph ; Green Philip G. ; Hussain Munir A. ; Repta Arnold J., Iontophoretic delivery of cell adhesion inhibitors.
  26. Carter, Darrick, Iontophoretic device and method of delivery of active agents to biological interface.
  27. Haak Ronald P. ; Gyory J. Richard ; Myers Robert M. ; Landrau Felix A. ; Sanders Harold F. ; Kleiner Lothar W. ; Hearney Linda M., Iontophoretic drug delivery apparatus.
  28. Joshi,Ashok V., Iontophoretic drug delivery systems.
  29. Beck, Jon E., Iontophoretic electrode with improved current distribution.
  30. Dinh Steven Minh ; Singh Parminder Bobby ; Comfort Ann Reese, Iontophoretic transdermal delivery and control of adverse side-effects.
  31. Tamarkin,Dov; Mavor,Daniela; Nitzan,Zvi; Arbel,Giora; Harel,Nurit; Luski,Shalom; Gross,Yossi, Kit, device and method for controlled delivery of oxidizing agent into the skin.
  32. Li, Zhengguo; Pan, Feng; Lim, Keng Pang; Wu, Dajun; Yu, Rongshan; Feng, Genan; Wang, Dusheng, Method and an apparatus for controlling the rate of a video sequence; a video encoding device.
  33. Phipps Joseph B., Method and apparatus for controlled environment electrotransport.
  34. Phipps Joseph B., Method and apparatus for controlled environment electrotransport.
  35. Phipps Joseph B. (Plymouth MN), Method and apparatus for controlled environment electrotransport.
  36. Sembrowich, Walter L.; Anderson, Carter R.; Kennedy, William R., Method and apparatus for non-invasively monitoring plasma glucose levels.
  37. Sakamoto, Fernanda Hidemi; Anderson, Richard Rox; Farinelli, William A.; Doukas, Apostolos G., Method and apparatus for optical inhibition of photodynamic therapy.
  38. Pesach, Benny; Bitton, Gabriel; Nagar, Ron; Weiss, Ram, Method and device for drug delivery.
  39. Pesach, Benny; Bitton, Gabriel; Weiss, Ram; Nagar, Ron, Method and device for drug delivery.
  40. Pesach, Benny; Nagar, Ron; Bitton, Gabriel; Weiss, Ram, Method and device for drug delivery.
  41. Charles B. Nemeroff ; Clinton D. Kilts, Method and devices for transdermal delivery of lithium.
  42. Guy Richard ; Rao Girish ; Glikfeld Peretz,ILX ; Cullander Christopher ; Hinz Robert S., Method for the iontophoretic non-invasive determination of the in vivo concentration level of glucose.
  43. Stephen Robert L. ; Stohrer Manfred,DEX ; Fontanella Umberto,ITX ; Griffith Donald P. ; Lugnani Franco,ITX ; Rossi Cino,ITX ; Eruzzi Silvio,ITX, Method of treating dysfunctional bladder syndromes by electromotive drug administration.
  44. Visco, Steven J.; Nimon, Yevgeniy S.; Katz, Bruce, Protected lithium electrodes for electro-transport drug delivery.
  45. Ledger Philip W. (Carlton GBX) Cormier Michel J. N. (Mountain View CA) Campbell Patricia S. (Palo Alto CA), Reduction of skin irritation during electrotransport delivery.
  46. Ledger Philip W.,GBX ; Cormier Michel J. N. ; Campbell Patricia S., Reduction of skin irritation during electrotransport delivery.
  47. Ledger Philip W.,GBX ; Cormier Michel J.N. ; Campbell Patricia S., Reduction of skin irritation during electrotransport delivery.
  48. Eischen, Kathleen A.; Anderson, Carter R.; Morris, Russell L., Sacrificial electrode design and delivery species suitable for prolonged iontophoresis application periods.
  49. Carter, Darrick; Hoyt, Joshua K.; Thorne, James; Seitz, Forrest, Systems, devices, and methods for powering and/or controlling devices, for instance transdermal delivery devices.
  50. Sibalis Dan (Stony Brook NY), Transdermal drug applicator and electrodes therefor.
  51. Miller, David J.; Li, Kevin; Higuchi, William I., Use of background electrolytes to minimize flux variability during iontophoresis.
  52. Johnson Michael T. V. (Minneapolis MN) Lee Nina H. (Richfield MN), pH buffered electrode for medical iontophoresis.
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