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Hemostatic agent composed of collagen/gelatin and protamine 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-037/08
  • A61L-015/01
  • A61L-017/00
  • C08L-089/06
출원번호 US-0087966 (1987-08-17)
우선권정보 JP-0242472 (1984-11-19)
발명자 / 주소
  • Miyata Teruo (Tokyo JPX) Kodaira Kazuhiko (Mitaka JPX) Furuse Masayasu (Sagamihara JPX) Noishiki Yasuharu (Tottori JPX)
출원인 / 주소
  • Koken Co., Ltd. (Tokyo JPX 03)
인용정보 피인용 횟수 : 65  인용 특허 : 0

초록

This invention relates to a hemostatic agent used in surgical operations, which can be produced in two ways: one blending collagen/gelatin with protamine, the other blending collagen/gelatin with protamine and a bi-functional cross-linking agent so as to make said collagen/gelatin have a covalent bo

대표청구항

A method of controlling bleeding comprising applying to a bleeding tissue a hemostatic agent composed of collagen or gelatin and protamine.

이 특허를 인용한 특허 (65)

  1. Hannam Peter Henry (Worthing GBX) Allison Richard Dale (Woodinville WA), Assembly for sealing a puncture in a vessel.
  2. Izoret Georges,FRX, Bioadhesive; preparation procedure and device for the application of a bioadhesive; and hardeners for a bioadhesive.
  3. Haaga John R., Biopsy needle.
  4. Lafontaine, Daniel M.; Ungs, Mark T.; Drasler, William J.; Zhong, Sheng-Ping (Samuel), Closure device with textured surface.
  5. Kakimoto Fumio (Gifu JPX) Asakawa Naoki (Gifu JPX) Ishibashi Yasuo (Gifu JPX) Miyake Yasuo (Aichi JPX), Composition containing tissue plasminogen activator.
  6. Janzen Ernst (GR Laren NLX) Ruttgers Gunter (Stolberg DEX) Saper Lawrence (New York NY), Device and method for sealing puncture wounds.
  7. Janzen Ernst,NLX ; Ruttgers Gunter,DEX ; Saper Lawrence, Device and method for sealing puncture wounds.
  8. Janzen Ernst,NLX ; Ruttgers Gunter,DEX ; Saper Lawrence, Device and method for sealing puncture wounds.
  9. Janzen Ernst,NLX ; Ruttgers Gunter,DEX ; Saper Lawrence ; Wolvek Sid, Device and method for sealing puncture wounds.
  10. Janzen Ernst,NLX ; Ruttgers Gunther,DEX ; Saper Lawrence ; Wolvek Sid, Device and method for sealing puncture wounds.
  11. Janzen,Ernst; Ruttgers,Gunter; Saper,Lawrence, Device and method for sealing puncture wounds.
  12. Larsen, Kristian; Sabra, Mads, Device for promotion of hemostasis and/or wound healing.
  13. Larsen, Kristian; Sabra, Mads, Device for promotion of hemostasis and/or wound healing.
  14. Katsaros Georges (Jupille BEX) Thomas David G. (Town and Country MO) Allison Richard D. (St. Louis MO), Device for sealing hemostatic incisions.
  15. Kensey Kenneth (Hinsdale IL), Device for sealing percutaneous puncture in a vessel.
  16. Larsen, Kristian, Dry composition comprising an extrusion enhancer.
  17. Larsen, Kristian, Dry haemostatic composition.
  18. Larsen, Kristian, Dry haemostatic composition.
  19. Qian, Zhen; Osawa, A. Edward; Reich, Cary J., Dry hemostatic compositions and methods for their preparation.
  20. Qian, Zhen; Osawa, A. Edward; Reich, Cary J., Dry hemostatic compositions and methods for their preparation.
  21. Qian, Zhen; Osawa, A. Edward; Reich, Cary J.; Wallace, Donald G.; Shargill, Narinder S.; Vega, Felix, Dry hemostatic compositions and methods for their preparation.
  22. Wallace Donald G. ; Reich Cary J. ; Shargill Narinder S. ; Vega Felix ; Osawa A. Edward, Fragmented polymeric compositions and methods for their use.
  23. Wallace Donald G. ; Reich Cary J. ; Shargill Narinder S. ; Vega Felix ; Osawa A. Edward, Fragmented polymeric compositions and methods for their use.
  24. Wallace, Donald G.; Reich, Cary J.; Shargill, Narinder S.; Vega, Felix; Osawa, A. Edward, Fragmented polymeric compositions and methods for their use.
  25. Wallace, Donald G.; Reich, Cary J.; Shargill, Narinder S.; Vega, Felix; Osawa, A. Edward, Fragmented polymeric compositions and methods for their use.
  26. Wallace, Donald G.; Reich, Cary J.; Shargill, Narinder S.; Vega, Felix; Osawa, A. Edward; Qian-Wallis, Zhen, Fragmented polymeric compositions and methods for their use.
  27. Wallace, Donald G.; Reich, Cary J.; Shargill, Narinder S.; Vega, Felix; Osawa, A. Edward; Qian-Wallis, Zhen, Fragmented polymeric compositions and methods for their use.
  28. Møller, Lene; Devantier, Kristina; Wulff, Trine; Sabra, Mads Christian, Haemostatic composition comprising hyaluronic acid.
  29. Wolff, Jørgen, Haemostatic kit, a method of preparing a haemostatic agent and a method of promoting haemostasis.
  30. Ilan, Erez; Faingold, Omri; Freizus, Nataly; Eavri, Ronen; Looney, Dwayne; Dhanaraj, Sridevi; Galloway, James; Danker, Walter, Hemostatic composition.
  31. Hedrich, Hans Christian; Hoefinghoff, Joris; Gorna, Katarzyna, Hemostatic compositions.
  32. McCoy, Jill; Dwyer, Joseph F.; Yang, Ziping, Hemostatic compositions.
  33. Cochrum,Kent C.; Jemtrud,Susan, Hemostatic compositions and methods for controlling bleeding.
  34. Pendharkar, Sanyog M.; Gorman, Anne J., Hemostatic compositions containing sterile thrombin.
  35. Ilan, Erez; Faingold, Omri; Freizus, Nataly; Eavri, Ronen; Looney, Dwayne; Dhanaraj, Sridevi; Galloway, James; Danker, Walter, Hemostatic mixture of cellulose-based short and long fibers.
  36. Kensey Kenneth ; Nash John E. ; Evans Douglas G., Hemostatic puncture closure system including closure locking means and method of use.
  37. Hedrich, Hans Christian; Hoefinghoff, Joris, Hemostatic sponge.
  38. Hedrich, Hans Christian; Hoefinghoff, Joris, Hemostatic sponge.
  39. Hedrich, Hans Christian; Hoefinghoff, Joris; Rhee, Woonza M.; Osawa, Atsushi Edward, Hemostatic sponge.
  40. Hedrich, Hans Christian; Hoefinghoff, Joris; Rhee, Woonza M.; Osawa, Atsushi Edward, Hemostatic sponge.
  41. Hedrich, Hans Christian; Hoefinghoff, Joris; Rhee, Woonza M.; Osawa, Atsushi Edward, Hemostatic sponge.
  42. Hoefinghoff, Joris; Hedrich, Hans Christian, Hemostatic sponge.
  43. Timothy Alan Abrahamson, Insertion assembly and method of inserting a hemostatic closure device into an incision.
  44. Fowler Bradford C., Insertion assembly and method of inserting a vessel plug into the body of a patient.
  45. Fowler Bradford C. (Woodinville WA), Insertion assembly and method of inserting a vessel plug into the body of a patient.
  46. Fowler Bradford C. (Woodinville WA), Insertion assembly and method of inserting a vessel plug into the body of a patient.
  47. Odar, Johann; Nistor-Gallo, Raymond, Method for directed cell in-growth and controlled tissue regeneration in spinal surgery.
  48. Petter-Puchner, Alexander; Redl, Heinz, Method for the improvement of mesh implant biocompatibility.
  49. Petter-Puchner, Alexander; Redl, Heinz, Method for the improvement of mesh implant biocompatibility.
  50. Nash John E. ; Evans Douglas G. ; Kensey Kenneth, Method of deploying percutaneous puncture closure.
  51. Odar, Johann; Sepehrnia, Abolghassem; Schachtler, Ralph; Stemberger, Axel W., Methods for repairing and regenerating human dura mater.
  52. Ueno Ryuzo (Nishinomiya JPX) Fujita Yatsuka (Nishinomiya JPX) Yamamoto Munemitsu (Nishinomiya JPX) Kozakai Hiroshi (Nishinomiya JPX), Multiplication inhibitor for Bacillus cereus.
  53. Goessl, Andreas, Process for making dry and stable hemostatic compositions.
  54. Goessl, Andreas; Osawa, Atsushi Edward; Reich, Cary J., Process for making dry and stable hemostatic compositions.
  55. Goessl, Andreas; Osawa, Atsushi Edward; Reich, Cary J., Process for making dry and stable hemostatic compositions.
  56. Goessl, Andreas; Osawa, Atsushi Edward; Reich, Cary J., Process for making dry and stable hemostatic compositions.
  57. Fleckenstein Peter (Fuldabrck DEX) Werner Heinz-Helmut (Melsungen DEX), Process for the preparation of a vessel prosthesis impregnated with crosslinked gelatin.
  58. Noishiki Yasuharu,JPX, Prosthesis containing bioabsorbable materials insolubilized without chemical reagents and method of making the same.
  59. Zhong, Sheng-Ping; Helmus, Michael N.; Ungs, Mark T.; Lafontaine, Daniel M., Puncture hole sealing device.
  60. Rhee, Woonza M.; Reich, Cary J.; Osawa, A. Edward; Vega, Felix, Rapidly acting dry sealant and methods for use and manufacture.
  61. Rhee, Woonza M.; Reich, Cary J.; Osawa, A. Edward; Vega, Felix, Rapidly acting dry sealant and methods for use and manufacture.
  62. Muijs Van De Moer Wouter M. (Grindweg 56 3055 VB Rotterdam NLX) Rienks Rienk (Mennestraat 17 3882 An Putten NLX), Sealing device.
  63. Muijs Van De Moer,Wouter Matthijs; Rienks,Rienk, Sealing device.
  64. Odar, Johann; Nistor-Gallo, Raymond; Caliari, Laura, Use of a regenerative biofunctional collagen biomatrix for treating visceral or parietal defects.
  65. Larsen, Kristian; Mortensen, Michael Wrang, Vacuum expanded dry composition and syringe for retaining same.
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