초록 ▼

A bandage assembly for percutaneous administration of a medicament generates sonic vibrations to produce sonophoresis. The assembly has a bandage member with a cavity containing a medicament and having a piezoelectric polymer element extending thereacross. An sonic generator is coupled to the piezoe

A bandage assembly for percutaneous administration of a medicament generates sonic vibrations to produce sonophoresis. The assembly has a bandage member with a cavity containing a medicament and having a piezoelectric polymer element extending thereacross. An sonic generator is coupled to the piezoelectric polymer element to supply it with energy to produce sonic vibrations perpendicular to the skin to drive the medicament into the pores. A second piezoelectric polymer element may surround the cavity to generate vibrations parallel to the skin to stretch the pores.

대표청구항 ▼

A bandage assembly for percutaneous administration of a medicament comprising: a. a bandage member having inner and outer surfaces and a cavity functionally opening on said inner surface thereof, said bandage member including a body element extending across said cavity adjacent said outer surface of

A bandage assembly for percutaneous administration of a medicament comprising: a. a bandage member having inner and outer surfaces and a cavity functionally opening on said inner surface thereof, said bandage member including a body element extending across said cavity adjacent said outer surface of said bandage member and fabricated from a piezoelectric polymer to generate vibrations perpendicularly to said inner surface, said bandage member having said inner surface adapted to be placed against the skin; b. a medicament composition in said cavity; c. electrical leads on said body element to supply energy thereto; and d. sonic generator means connected to said leads to generate sonic vibrations in said body element to induce percutaneous transfer of the medicament composition, said vibrations being within a frequency range of about 20 Hz to 2 kHz.