초록 ▼

This invention relates to devices and to methods, diagnostic reagents and kits embodying such devices for use in ligand/anti-ligand assays and the qualitative or semi-quantitative detection of a substance of interest thereby through use of light or photon detecting systems such as reflectometers, co

This invention relates to devices and to methods, diagnostic reagents and kits embodying such devices for use in ligand/anti-ligand assays and the qualitative or semi-quantitative detection of a substance of interest thereby through use of light or photon detecting systems such as reflectometers, colorimeters, fluorimeters and the human eye. Such devices, methods and kits have applications in the biologic research and medical fileds for assaying drugs, hormones, peptides, proteins, enzymes, nucleic acids, antibodies, haptens, antibiotics, viri, infectious agents, tumor markers and the like, in the laboratory, the physicians\office, the veterinarian\s office and the home.

대표청구항 ▼

A method for assaying one or more samples for the presence of at least one ligand with the aid of a device for assaying one or more samples for the presence of a ligand by forming within the device a detectable reaction product of the ligand with at least one anti-ligand therefor and detecting the r

A method for assaying one or more samples for the presence of at least one ligand with the aid of a device for assaying one or more samples for the presence of a ligand by forming within the device a detectable reaction product of the ligand with at least one anti-ligand therefor and detecting the reaction product, the device comprising: a plastic member defining at least one well having a bottom, the well comprising at least one immobilized anti-ligand; and a plurality of spaced projections extending upward from the well bottom to increase the surface area thereof, the projections being spaced to define interconnecting channels therebetween; the method comprising: (1) introducing the sample into the well; (2) forming in the well a ligand/anti-ligand reaction product; and (3) detecting the ligand/anti-ligand reaction product capable of detection.