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Bioadhesive composition and method of treatment therewith 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/22
  • A61K-009/52
  • A61K-009/24
출원번호 US-0909960 (1986-09-22)
발명자 / 주소
  • Robinson Joseph R. (Madison WI)
출원인 / 주소
  • Bio-Mimetics, Inc. (Lexington MA 02)
인용정보 피인용 횟수 : 60  인용 특허 : 13

초록 ▼

A controlled release treatment composition and method of use are disclosed. The composition includes a bioadhesive and an effective amount of a treating agent. The bioadhesive is a water-swellable, but water-insoluble, fibrous, cross-linked carboxy-functional polymer containing (a) a plurality of re

대표청구항 ▼

A controlled release treatment composition including a bioadhesive and an effective amount of fluorometholone, said bioadhesive comprising a water-swellable, but water-insoluble, fibrous, cross-linked carboxy-functional polymer, said polymer sized to pass through a 100 mesh sieve screen, U.S. Standa

이 특허에 인용된 특허 (13)

  1. Sidman Kenneth R. (Wayland MA), Biodegradable, implantable drug delivery depots, and method for preparing and using the same.
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  5. Sair Louis (Evergreen Park IL) Sair Ralph A. (Lincolnwood IL), Encapsulation of active agents as microdispersions in homogeneous natural polymeric matrices.
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  6. Nagai Tsuneji (Chofu JPX) Machida Yoshiharu (Kawasaki JPX) Suzuki Yoshiki (Hino JPX) Ikura Hiroshi (Hino JPX), Method and preparation for administration to the mucosa of the oral or nasal cavity.
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  7. Shell John W. (Hillsborough CA) Gale Robert M. (Mountain View CA), Ocular preparation housing steroid in two different therapeutic forms.
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  8. Edgren, David, Process for preparing osmotic device.
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  9. Kaetsu Isao (Takasaki JPX) Yoshida Masaru (Takasaki JPX), Process for producing a multi-layered slow release composite.
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  10. Shibata Tadashi (Yokohama JPX), Semiconductor device MOSFET with V-shaped drain contact.
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  11. Suzuki Yoshiki (Hino JPX) Ikura Hiroshi (Hino JPX) Yamashita Gentaro (Koganei JPX), Slow-releasing medical preparation to be administered by adhering to a wet mucous surface.
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  12. Schoenwald Ronald D. (Fort Worth TX) Roehrs Robert E. (Fort Worth TX), Sustained release ophthalmic drug dosage.
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  13. Mueller Karl F. (New York NY) Good William R. (Yorktown Heights NY), Water-insoluble hydrophilic copolymers.
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  2. Zhang, Liangfang; Radovic-Moreno, Aleksandar F.; Gu, Frank X.; Alexis, Frank; Langer, Robert S.; Farokhzad, Omid C., Amphiphilic compound assisted nanoparticles for targeted delivery.
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  3. Lee, Bruce P.; Vollenweider, Laura; Murphy, John L.; Xu, Fangmin; Dalsin, Jeffrey L.; Virosco, Jeanne; Lew, William; White, Jed, Bioadhesive constructs.
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  4. Marchant, Nancy S., Bioadhesive hydrogels with functionalized degradable crosslinks.
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  5. Edith Mathiowitz ; Donald E. Chickering, III ; Jules Serge Jacob, Bioadhesive microspheres and their use as drug delivery and imaging systems.
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  6. Mathiowitz Edith ; Chickering ; III Donald ; Jacob Jules S., Bioadhesive microspheres and their use as drug delivery and imaging systems.
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  7. Lee, Bruce P., Biomimetic compounds and synthetic methods therefor.
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  8. Lee, Bruce P., Biomimetic compounds and synthetic methods therefor.
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  9. Lee, Bruce P., Biomimetic compounds and synthetic methods therefor.
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  10. Messersmith, Phillip B.; Lee, Haeshin H.L.; Lee, Bruce P., Biomimetic modular adhesive complex: materials, methods and applications therefore.
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  11. Jon, Sangyong; Farokhazd, Omid C.; Langer, Robert S.; Cheng, Jianjun, Coated controlled release polymer particles as efficient oral delivery vehicles for biopharmaceuticals.
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  12. Messersmith, Phillip B.; Dalsin, Jeffrey L.; Lee, Bruce P.; Burke, Sean A., DOPA-functionalized, branched, poly(aklylene oxide) adhesives.
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  16. Gong, Glen; Dieck, Ronald, Glue compositions for lung volume reduction.
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  17. Iannacone, Matteo; Alexis, Frank; Basto, Pamela; Moseman, Elliott Ashley; Shi, Jinjun; Langer, Robert S.; Farokhzad, Omid C.; von Andrian, Ulrich; Tonti, Elena, Immunonanotherapeutics that provide IGG humoral response without T-cell antigen.
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  18. Plate Nikolai Alfredovich (Moscow RUX) Valuev Lev Ivanovich (Moscow RUX) Valueva Tatyana Alexandrovna (Moscow RUX) Staroseltseva Ljudmila Konstantinovna (Moscow RUX) Ametov Alexandr Sergeevich (Mosco, Insulin-containing polymer composition for oral administration.
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  19. Spina ; Jr. Joseph (767 Woodlea Rd. Rosemont PA 19109) Weibel Michael K. (120 Gallows Hill Rd. West Redding CT 06896), Intralenticular cataract surgical procedure.
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  20. Franz, G. Andrew; Strauss, Elaine A.; DiMenna, Philip A.; Gemma, Rocco L., Levothyroxine compositions and methods.
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  21. Gong, Glen; Dieck, Ronald, Lung volume reduction using glue composition.
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  23. Cima, Michael J.; Ye, Hongye; Del Carmen, Marcela; Birrer, Michael, Medicament, method, and drug delivery device for treatment of ovarian cancer.
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  24. Franz,G. Andrew; Strauss,Elaine A.; DiMenna,Phillip A.; Gemma,Rocco L., Methods of administering levothyroxine pharmaceutical compositions.
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  25. Huang,Yanbin; Kim,Jaeho, Methods of making functional biodegradable polymers.
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  26. Karnik, Rohit; Gu, Frank X.; Basto, Pamela; Cannizzaro, Chris; Khademhosseini, Alireza; Langer, Robert S.; Farokhzad, Omid C., Microfluidic synthesis of organic nanoparticles.
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  27. Shull, Kenneth R.; Guvendiren, Murat; Messersmith, Phillip B; Lee, Bruce P, Modified acrylic block copolymers for hydrogels and pressure sensitive wet adhesives.
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  28. Haberstroh, Karen M.; Webster, Thomas J.; Thapa, Anil; Miller, Derick C., Nano-structured polymers for use as implants.
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  29. Webster, Thomas J.; McKenzie, Janice L., Nanofibers as a neural biomaterial.
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  33. Hoffman Allan S. ; Hayashi Yoshiki,JPX, Pegylated drug complexed with bioadhesive polymer suitable for drug delivery and methods relating thereto.
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  34. Messersmith, Phillip B.; Barron, Annelise; Statz, Andrea; Meagher, Robert, Peptidomimetic polymers for antifouling surfaces.
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