초록 ▼

An interface generally useful for liquid chromotography systems and methods is provided for the separation of an analyte of interest from a liquid solvent. The interface provides for separation and collection of solvent and the analyte of interest in a gaseous molecular state. In this manner, the ab

An interface generally useful for liquid chromotography systems and methods is provided for the separation of an analyte of interest from a liquid solvent. The interface provides for separation and collection of solvent and the analyte of interest in a gaseous molecular state. In this manner, the ability to detect, identify, and quantify the analyte of interest using a variety of specific and non-specific detectors is made possible.

대표청구항 ▼

An interface useful for separating an analyte of interest from an admixture with a liquid solvent, said interface comprising: conduit means for conveying a liquid admixture comprising an analyte of interest and a liquid solvent; heating means for vaporizing a liquid admixture comprising an analyte o

An interface useful for separating an analyte of interest from an admixture with a liquid solvent, said interface comprising: conduit means for conveying a liquid admixture comprising an analyte of interest and a liquid solvent; heating means for vaporizing a liquid admixture comprising an analyte of interest and a liquid solvent into a dry gaseous mixture comprising gaseous molecules of solvent and gaseous molecules of the analyte of interest; an adiabatic expansion chamber without internal mechanical means for moving a liquid admixture, said adiabatic expansion chamber being adjacent to and in communication with said heating means and being under reduced pressure for adiabatic expansion and separation of a dry gaseous mixture whereby gaseous molecules of solvent of the gaseous mixture migrate substantially toward the internal periphery of said adiabatic expansion chamber and gaseous molecules of the analyte of interest of the gaseous mixture migrate substantially toward the internal center of said adiabatic expansion chamber; solvent gas collection means at the internal periphery of said adiabatic expansion chamber for collection of separated gaseous molecules of solvent; and analyte gas collection means at about the internal center of said adiabatic expansion chamber for collection of separated gaseous molecules of the analyte of interest.