초록 ▼

A multilayer analytical element exhibits improved precision in the assay of total lactate dehydrogenase (LDH). The element also provides reduced susceptibility to total protein and hemoglobin interferences in the assay. The element contains a porous spreading layer composed of a particulate structur

A multilayer analytical element exhibits improved precision in the assay of total lactate dehydrogenase (LDH). The element also provides reduced susceptibility to total protein and hemoglobin interferences in the assay. The element contains a porous spreading layer composed of a particulate structure. A fluorinated surfactant is also used in the assay. This surfactant has one or more fluorocarbon moieties provided, that when the surfactant has more than one such moiety, they are substantially linear. The surfactant can be incorporated in the element or added at the time of the assay.

대표청구항 ▼

A dry analytical element for the determination of total lactate dehydrogenase (LDH) comprising a support having thereon a porous spreading layer composed of a particulate structure comprising a plurality of particles being bonded to each other on surface areas of said particles which are adjacent, w

A dry analytical element for the determination of total lactate dehydrogenase (LDH) comprising a support having thereon a porous spreading layer composed of a particulate structure comprising a plurality of particles being bonded to each other on surface areas of said particles which are adjacent, where said adjacent particles form a coherent, three dimensional lattice which is essentially non-swellable to an aqueous liquid, said element further comprising a saturated or unsaturated fluorinated surfactant containing one or more fluorocarbon moieties each having from 4 to 16 carbon atoms and from 8 to 33 fluorine atoms, and each of said moieties having a ratio of fluorine atoms to carbon atoms of about 2:1, provided that when said surfactant contains more than one such moiety, said moieties have up to two fluorinated or unfluorinated methyl branches.