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A method for disinfecting a medical device comprising the steps of immersing a medical device in a hydrogen peroxide solution for a time sufficient to disinfect said device, decomposing any residual hydrogen peroxide by use of a catalytically effective amount of a protein capable of decomposing hydr

A method for disinfecting a medical device comprising the steps of immersing a medical device in a hydrogen peroxide solution for a time sufficient to disinfect said device, decomposing any residual hydrogen peroxide by use of a catalytically effective amount of a protein capable of decomposing hydrogen peroxide, said protein being immobilized on a composite article, said composite article comprising in sequence a support, a layer of protein immobilizer compound, and a biologically active protein. The surface modification treatment is a gelled network of inorganic oxide particles or a plasma treatment.

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A method for disinfecting a medical device comprising the steps: (a) immersing a medical device in a hydrogen peroxide solution for a time sufficient to disinfect said device, (b) decomposing any residual hydrogen peroxide by use of a catalytically effective amount of a protein capable of decomposin

A method for disinfecting a medical device comprising the steps: (a) immersing a medical device in a hydrogen peroxide solution for a time sufficient to disinfect said device, (b) decomposing any residual hydrogen peroxide by use of a catalytically effective amount of a protein capable of decomposing hydrogen peroxide, said protein being immobilized on a composite article, comprising in sequence: (1) a polymeric fibrous support, wherein said support has been subjected to a surface modification treatment to provide binding sites thereon, said treatment providing a layer of inorganic oxide having a uniform thickness when dried in the range of 2 to 500 nm to provide binding sites thereon, or being a radio frequncy or microwave plasma treatment carried out at a frequency of 10 to 125 kilohertz with a power density in the range of 0.05 to 2.25 w/cm2 generated between two electrodes in a gas at a pressure in the range of 10 mtorr to 10 torr, (2) a layer of a protein immobilizer compound comprising a polymer or a silane-functional compound, and (3) a biological active protein bound to said layer of protein immobilizer compound and capable of decomposing hydrogen peroxide.