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A solid, controlled release, pharmaceutical composition comprising an active ingredient incorporated in a matrix comprising a first substance selected from a water soluble polydextrose and a water soluble cyclodextrin and a second substance selected from a C12-C36 fatty alcohol and a polyalkylene gl

A solid, controlled release, pharmaceutical composition comprising an active ingredient incorporated in a matrix comprising a first substance selected from a water soluble polydextrose and a water soluble cyclodextrin and a second substance selected from a C12-C36 fatty alcohol and a polyalkylene glycol. Preferably the first substance is a cyclodextrin, especially a beta-cyclodextrin, while the second substance is a C14-C22 fatty alcohol, especially stearyl alcohol, cetyl alcohol, cetostearyl alcohol or myristyl alcohol. The matrix may also contain a cellulose ether, especially a hydroxyalkylcellulose or a carboxyalkylcellulose.

대표청구항 ▼

A solid, controlled release pharmaceutical composition comprising a pharmaceutically active ingredient incorporated in a matrix comprising a first substance selected from the group consisting of a water soluble polydextrose, a water soluble cyclodextrin and a cellulose ether, and a second substance

A solid, controlled release pharmaceutical composition comprising a pharmaceutically active ingredient incorporated in a matrix comprising a first substance selected from the group consisting of a water soluble polydextrose, a water soluble cyclodextrin and a cellulose ether, and a second substance selected from the group consisting of a C12-C36 fatty alcohol and a polyalkylene glycol.