[특허]Method for promoting tissue adhesion to soft tissue implants

[미국특허] Method for promoting tissue adhesion to soft tissue implants 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	A61F-002/02
출원번호	US-0168894 (1988-03-16)
발명자 / 주소	von Recum Andreas F. (Clemson SC) Cooke Francis W. (Clemson SC)
출원인 / 주소	Clemson University (Clemson SC 02)
인용정보	피인용 횟수 : 71 인용 특허 : 6

초록 ▼

A soft tissue implant comprises a flexible main body portion, having tissue-facing surfaces and a thin layer of pure titanium covering the tissue-facing surfaces. A method of promoting tissue adhesion of a soft tissue host to the tissue-facing surfaces of a soft tissue implant comprising a strip of polyethylene terephthalate velour comprises the steps of cleaning the strip with a low-residue detergent and rinsing same with fresh distilled water; refluxing the strip in distilled water for one hour at a temperature of less than 30°C.; drying the strip in a room-temperature desicator for several days; sterilizing the strip and packaging same; degasing the strip and storing same in a dust-free environment; removing the strip from the packaging and mounting the strip in a vacuum evaporator at an approximate angle of incidence of 90°from a pure titanium metal evaporant; evacuating the vacuum evaporator to a vacuum of about 2×10-5 Torr; evaporating the titanium by direct resistence heating same; coating the strip with a layer of pure titanium on the order of one micron thick; and resterilizing and implanting the titanium-coated strip into the tissue host.

대표청구항 ▼

A method of promoting tissue adhesion of a host\s soft tissue bed to a soft tissue implant having a main body portion with tissue-facing surfaces, the method comprising the steps of: coating the tissue-facing surfaces of the main body portion with a layer of pure titanium; sterilizing the titanium coated implant; forming a thin layer of titanium oxide over the pure titanium layer as the free surface of the implant; and implanting the titanium coated implant into the host\s soft tissue bed. A method of promoting tissue adhesion of a host\s soft tissue bed to the tissue-facing surfaces of a strip of polyethylene terephthalate velour, the method comprising the steps of: cleaning the strip with a low-residue detergent and rinsing same with fresh distilled water; refluxing the strip in distilled water at a temperature of less than 30°C. for more than one hour; drying the strip in a room-temperature desiccator for more than one day; degassing, sterilizing, packaging and storing the strip in a dust-free environment; removing the strip from the packaging and mounting the strip in a vacuum evaporator at an approximate angle of incidence of 90°from the source of the vacuum evaporator, said source comprising a pure titanium metal evaporant; evacuating the vacuum evaporator to a vacuum of about 2 ×10-5 Torr; resistance heating the titanium evaporant until the strip is coated with a layer of pure titanium on the order of 1 micron thick; resterilizing the titanium coated strip; forming a thin layer of titanium oxide over the pure titanium layer as the free surface of the implant; and implanting the titanium coated strip into the host\s soft tissue bed.

이 특허에 인용된 특허 (6) 인용/피인용 타임라인 분석

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Jones Robert N. (Fairport NY) Heeks Robert E. (Penfield NY), Electrophotographic imaging member and process comprising sputtering titanium on substrate.
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[미국특허] Method for promoting tissue adhesion to soft tissue implants 원문보기

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[미국특허] Method for promoting tissue adhesion to soft tissue implants 원문보기

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