[특허]System for intravenous delivery of a beneficial drug at a regulated rates

[미국특허] System for intravenous delivery of a beneficial drug at a regulated rates 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	A61K-009/22
출원번호	US-0854452 (1986-04-21)
발명자 / 주소	Theeuwes Felix (Los Altos CA)
출원인 / 주소	Alza Corporation (Palo Alto CA 02)
인용정보	피인용 횟수 : 24 인용 특허 : 26

초록 ▼

A formulation chamber is disclosed comprising a wall surrounding a space containing a beneficial agent. The formulation chamber has an inlet for admitting a fluid into the chamber and an outlet for letting the fluid containing the agent leave the chamber. The chamber can additionally comprise a film for regulating the rate of release from the chamber, and optionally a filter. The chamber is adapted for use in an intraveous delivery system for delivering the fluid containing the agent to a patient. A method also is disclosed for using the formulation chamber.

대표청구항 ▼

A drug formulation chamber for use with an intravenous delivery system for administering a beneficial drug at a controlled rate for the care of a patient on intravenous therapy, which formulation chamber is moisture proof and comprises: (a) a wall that surrounds an internal lumen; (b) an inlet in the wall of the formulation chamber adapted and sized for placing the formulation chamber into an intravenous delivery system and for letting an intravenously administrable fluid enter the formulation chamber; (c) a beneficial intravenously administrable drug in a therapeutically effective amount up to 20 grams in the formulation chamber, said drug in a pharmaceutically acceptable solid dosage form selected from the group consisting of crystalline, microcrystalline, particle, pellet, granule, powder, dried, lyophilized, compressed forms and friable layers, and wherein when the formulation chamber is in operation the beneficial drug is added to fluid that enters the formulation chamber at a rate regulated by the fluid flow through the intravenous delivery system and by the rate of dissolution of the solid dosage form in the fluid that enters the formulation chamber to provide a fluid drug formulation acceptable for intravenous therapy; and, (d) an outlet in the wall of the formulation chamber adapted and sized for placing the formulation chamber in an intravenous delivery system for letting the fluid drug formulation leave the formulation chamber.

이 특허에 인용된 특허 (26) 인용/피인용 타임라인 분석

Hyden Viktor Holger (Prastgardsgaten 2 Goteborg SW) Hasselblad Fritz Victor (St. Eriks Torg 3 Goteborg SW), Apparatus and method for selectively separating amino acids and defined proteins in blood.
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Shukla Vishnu S. (c/o Newcastle General Hospital ; Department of Radiation and Oncology ; Westgate Rd. Newcastle upon Tyne NE4 6BE GB2), Apparatus for administering intravenous drugs.
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Dietrich Joseph W. (4653 Bromfield Ave. Virginia Beach VA 23455) Lubimov Eugene J. (668 Sirine Ave. Virginia Beach VA 23458), Apparatus for long term intravenous administration of diluted incompatible multiple medications.
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Franetzki Manfred (Uttenreuth DEX), Apparatus for supplying medication to the human or animal body.
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Reti Adrian R. (Cambridge MA), Arrangement for intravenous administration or the like.
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Sun Anthony M. (Willowdale CAX) Parisius Wolf J. (Willowdale CAX), Artificial endocrine pancreas.
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Virag Robert A. (Lake Zurich IL), Burette chamber for use with intravenous solution administration set.
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Theeuwes Felix (Los Altos CA), Device for dispensing drug by combined diffusional and osmotic operations.
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Lundquist Ingemar H. (Oakland CA), Drug dispenser for use with intravenous feeding pump.
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Muetterties Andrew J. (Gages Lake IL) Genese Joseph N. (Waukegan IL), Equipment sets and system for the sequential administration of medical liquids at dual flow rates.
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Edwards ; James H., Filter unit.
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Wolfe Allan M. (South Laguna CA) Davenport James M. (Tustin CA) Theeuwes Felix (Los Altos CA) Yum Su I. (Sunnyvale CA), In-line drug dispenser for use in intravenous therapy.
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Harris Dale C. (Fairland IN) Hargrove William W. (Indianapolis IN), Intravenous administration system for dry medicine.
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Zeidler ; Gunter ; Gunther ; Christian, Lubricating oil system.
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Zaffaroni Alejandro (Atherton CA), Microporous drug delivery device.
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Zaffaroni Alejandro (Atherton CA), Novel drug delivery device.
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Zaffaroni Alejandro (Atherton CA), Novel drug delivery device.
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Michaels Alan S. (San Francisco CA) Guillod Mark S. (Kaneohe HI), Osmotic bursting drug delivery device.
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Higuchi Takeru (Lawrence KS) Leeper Harold M. (Mountain View CA), Osmotic dispenser with means for dispensing active agent responsive to osmotic gradient.
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Theeuwes Felix (Los Altos CA), Osmotic system with volume amplifier for increasing amount of agent delivered therefrom.
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Urquhart John (Palo Alto CA) Theeuwes Felix (Los Altos CA), Parenteral administration.
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Urquhart John (Palo Alto CA) Theeuwes Felix (Los Altos CA), Parenteral controlled delivery.
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Langston Jimmy B. (San Jose CA) Leeper Harold (Mountain View CA) Wong Patrick S. (Palo Alto CA), Patient-care apparatus with chemoprophylactic system.
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Kaetsu Isao (Takasaki JPX) Yoshida Masaru (Takasaki JPX) Kumakura Minoru (Takasaki JPX), Process for preparing a polymer composition.
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Theeuwes, Felix, System for intravenous delivery of a beneficial agent.
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Urquhart John (Palo Alto CA) Theeuwes Felix (Los Altos CA), System for intravenous therapy.
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이 특허를 인용한 특허 (24) 인용/피인용 타임라인 분석

Woodworth,Archie; Reed,William; Adams,David J.; Martine, Jr.,John A.; Smith,Jeffery; Steeber,Michael; Korzeniewski,Kim, Apparatus for fabricating a reconstitution assembly.
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Jacobson, James D.; Bui, Tuan; Garchow, Stephen R.; Yardimci, Atif; Slepicka, James S., Fluid delivery system and flow control therefor.
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Jacobson, James D.; Bui, Tuan; Garchow, Stephen R.; Yardimci, Atif; Slepicka, James S., Fluid delivery system and flow control therefor.
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Jacobson, James D.; Bui, Tuan; Garchow, Stephen R.; Yardimci, Atif; Slepicka, James S., Fluid delivery system and flow control therefor.
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Aebischer Patrick (Providence RI) Galletti Pierre M. (Providence RI) Panol George (Warwick RI) Miracoli Luigi (Genoa ITX), Implantable delivery system for biological factors.
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Williams, John A.; Martine, Jr., John A., Method and apparatus for validation of sterilization.
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Williams, John A.; Martine, Jr., John A., Method and apparatus for validation of sterilization process.
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Fowles, Thomas A.; Weinburg, Robert J., Reconstitution assembly, locking device and method for a diluent container.
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Fowles Thomas A. ; Weinberg Robert J. ; Progar Thomas J., Septum for a sliding reconstitution device with seal.
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Fowles Thomas A. ; Weinberg Robert J. ; Progar Thomas J., Sliding reconstitution device for a diluent container.
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Fowles, Thomas A.; Weinberg, Robert J., Sliding reconstitution device for a diluent container.
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Fowles, Thomas A.; Weinberg, Robert J., Sliding reconstitution device for a diluent container.
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Fowles,Thomas A.; Weinberg,Robert J., Sliding reconstitution device for a diluent container.
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Fowles,Thomas A.; Weinberg,Robert J.; Progar,Thomas J., Sliding reconstitution device for a diluent container.
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Fowles Thomas A. ; Progar Thomas J. ; Weinberg Robert J. ; Fuller Craig A., Sliding reconstitution device with seal.
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Fowles Thomas A. ; Progar Thomas J. ; Weinberg Robert J. ; Fuller Craig A., Sliding reconstitution device with seal.
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Fowles Thomas A. ; Progar Thomas J. ; Weinberg Robert J. ; Fuller Craig A., Sliding reconstitution device with seal.
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Fowles Thomas A. ; Progar Thomas J. ; Weinberg Robert J. ; Fuller Craig A., Sliding reconstitution device with seal.
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Fowles Thomas A. ; Progar Thomas J. ; Weinberg Robert J. ; Fuller Craig A., Sliding reconstitution device with seal.
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Fowles, Thomas A.; Progar, Thomas J.; Weinberg, Robert J.; Fuller, Craig A., Sliding reconstitution device with seal.
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Fowles, Thomas A.; Progar, Thomas J.; Weinberg, Robert J.; Fuller, Craig A., Sliding reconstitution device with seal.
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Fowles Thomas A. ; Weinberg Robert J., Vial connecting device for a sliding reconstitution device for a diluent container.
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Fowles, Thomas A.; Weinberg, Robert J., Vial connecting device for a sliding reconstitution device for a diluent container.
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Fowles Thomas A. ; Weinberg Robert J. ; Progar Thomas J., Vial connecting device for a sliding reconstitution device with seal.
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A	생활필수품
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A62B-1/08	.. 윈치 또는 풀리에 제동기구가 있는 것

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[미국특허] System for intravenous delivery of a beneficial drug at a regulated rates 원문보기