Antiestrogens and their use in treatment of menopause and osteoporosis
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61K-031/535
A61K-031/445
A61K-031/40
A61K-031/19
출원번호
US-0143081
(1988-01-12)
발명자
/ 주소
Young Ronald L. (Houston TX)
출원인 / 주소
BCM Technologies, Inc. (Houston TX 02)
인용정보
피인용 횟수 :
66인용 특허 :
1
초록▼
Disclosed is a method for treating menopausal symptoms and treating and preventing osteoporosis, wherein a true antiestrogen is administered and estrogen is not. This treatment is effective for female osteoporosis and can also be used to treat male osteoporosis. Examples of true antiestrogens are cl
Disclosed is a method for treating menopausal symptoms and treating and preventing osteoporosis, wherein a true antiestrogen is administered and estrogen is not. This treatment is effective for female osteoporosis and can also be used to treat male osteoporosis. Examples of true antiestrogens are clomiphene, and its isomers, citrates and derivatives, as well as several other compounds which appear in the specification.
대표청구항▼
A method of treating and preventing bone tissue loss or osteoporosis in a patient, comprising administering a true antiestrogen selected from the group consisting of clomiphene, an isomer of clomiphene, a citrate of clomiphene, a derivative of clomiphene, tamoxifen, nafoxidine, CI-680, CI-628, CN-55
A method of treating and preventing bone tissue loss or osteoporosis in a patient, comprising administering a true antiestrogen selected from the group consisting of clomiphene, an isomer of clomiphene, a citrate of clomiphene, a derivative of clomiphene, tamoxifen, nafoxidine, CI-680, CI-628, CN-55,956-27, MER-25, U-11,555A, U-11,100A, ICI-46,669, ICI-46,474, diphenolhydrochrysene, erythro-MEA, Parke Davis CN-35,945, allenolic acid, cyclofenil, ethamoxytriphetol, and triparanol to said patient, without concomitant estrogen administration.
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이 특허에 인용된 특허 (1)
Jensen Pamela S. (Camden ME) Comite Florence (New Haven CT), Use of clomiphene to predict fertility in a human female.
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Black Larry J. (Indianapolis IN) Bryant Henry U. (Indianapolis IN) Cullinan George J. (Trafalgar IN), Sulfonate and carbamate derivatives of 3-aroylbenzo[B]thiophenes.
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