초록 ▼

A transdermal delivery device for delivering drugs, typically ionized drugs, from an aqueous reservoir is described. The device comprises an aqueous drug reservoir in the form of a gel confined between an impermeable backing member and a porous support structure. In preferred embodiments the support

A transdermal delivery device for delivering drugs, typically ionized drugs, from an aqueous reservoir is described. The device comprises an aqueous drug reservoir in the form of a gel confined between an impermeable backing member and a porous support structure. In preferred embodiments the support structure is the substrate to which is applied a porous or patterned in-line adhesive. A strippable release liner is preferably provided on the adhesive while in the package. The devices are usable to deliver drugs such as chlorpheniramine maelate, brompheneiramine maleate and scopolamine hydrobromide.

대표청구항 ▼

A medical device for the transdermal delivery of a highly ionized, fat-insoluble drug comprising, in combination: a. aqueous drug reservoir means comprising at least 50% water having said drug dissolved therein; b. receptacle means containing said reservoir means, said receptacle means being substan

A medical device for the transdermal delivery of a highly ionized, fat-insoluble drug comprising, in combination: a. aqueous drug reservoir means comprising at least 50% water having said drug dissolved therein; b. receptacle means containing said reservoir means, said receptacle means being substantially impermeable to the contents of said reservoir means; c. highly permeable reservoir retaining means disposed over the skin proximal surface of said aqueous reservoir means; and d. means for maintaining said medical device in permeation enhancer and drug transmitting relationship to the skin.