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Fluorescent lanthanide chelates 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C07F-005/00
  • G01N-033/533
  • C07D-213/38
  • C07D-213/55
출원번호 US-0149980 (1988-01-25)
우선권정보 SE-0002573 (1985-05-23)
발명자 / 주소
  • Kankare Jouko (Paljasp8E3 SF-206 10 Turku 61 FIX) Takalo Harri (Ursininkatu 13A4 SF-20100 Turku 10 FIX) Pasanen Paavo (Menninkaisenkatu 10E37 SF-20640 Ravattula FIX)
인용정보 피인용 횟수 : 26  인용 특허 : 21

초록

A fluorescing lanthanide chelate of a lanthanide cation and a compound having the structure [Figure] where X3, X4 and X5 that may be the same or different, each denotes a substituted ethynyl group, hydrogen, an alkyl group, an aryl group, a hydroxyl group, an alkoxyl group or an amino group, wherein

대표청구항

A fluorescing lanthanide chelate of a lanthanide cation and a compound having the structure: [Figure] wherein each of X3, X4 and X5, that can be the same or different, denotes a substituted ethynyl group directly attached to the pyridine ring, a hydrogen, an alkyl group, an aryl group, a hydroxyl gr

이 특허에 인용된 특허 (21)

  1. Evangelista Ramon A. (Scarborough CAX) Pollak Alfred (Toronto CAX), 1,10-phenanthroline derivatives and use in fluorescence immunoassays.
  2. Diery Helmut (Paris FR) Schrinner Elmar (Wiesbaden DT) Gunther Kurd (Diedenbergen ; Taunus DT) Schneider Gerhart (Schneidhain ; Taunus DT), Anti-microbially active surface-active agents.
  3. Ondetti Miguel A. (Princeton NJ) Cushman David W. (West Windsor NJ), Carboxyalkylacylamino acids.
  4. Sundberg Michael W. (Stanford CA) Meares Claude F. (Davis CA) Werthemann Lucius (Kaenelrain CH), Chelating agents.
  5. Hinshaw Jerald C. (Ogden UT) Toner John L. (Webster NY) Reynolds George A. (Rochester NY), Coumarin chelates.
  6. Theodoropulos Spyros (2964 Hickory St. Yorktown Heights NY 10598), Di-ureadopyridines and their chelates.
  7. Shen Tsung-Ying (Westfield NJ) Jones Howard (Holmdel NJ) Dorn Conrad P. (Plainfield NJ), Ethenyl derivatives of mercaptoalkylpyridines as anti-inflammatory agents.
  8. Soini Erkki (Turku FIX) Hemmil Ilkka (Turku FIX), Fluorescence spectroscopy assay means with fluorescent chelate of a lanthanide.
  9. Wieder Irwin (Los Altos CA), Fluorescent antibody composition for immunofluorometric assay.
  10. Frank David S. (Rochester NY) Sundberg Michael W. (Penfield NY), Fluorescent labels.
  11. Hinshaw Jerald C. (Ogden UT) Toner John L. (Webster NY) Reynolds George A. (Rochester NY), Fluorescent labels for immunoassay.
  12. Sherry A. Dean (Richardson TX), Gadolinium chelates as NMR contrast agents.
  13. Mitchell Robert S. (Webster Groves MO), Imino alkylimino phosphonates and method for preparing and using same.
  14. Wieder Irwin (Los Altos CA), Method and apparatus for improved analytical fluorescent spectroscopy.
  15. Hemmil Ilkka (Turku FIX) Dakubu Salifu (London GBX), Method for fluorescence spectroscopic determination of a biologically active substance.
  16. Noller Hans G. (1512 Basswood Cir. Glenview IL 60025), Method of determining extracellular antigens and antibodies.
  17. Baudouin Jacques (Viviers FRX) Caspar Jean-Pierre (Viviers FRX) Gaillard Jacques (Villeneuve de Berg FRX), Method to produce mineral fillers containing hydrated calcium monocarboaluminate.
  18. Moser Paul (Riehen CHX), Phosphonate stabilizers.
  19. Di Battista Piero (San Donato Milanese ITX) Fontanelli Renzo (Milan ITX) Gratani Francesco (Sesto San Giovanni ITX) Nelli Giuseppe (Milan ITX), Piperidine phosphite stabilizers for polymers and polymers stabilized thereby.
  20. Toner John L. (Webster NY), Polypyridine Fluorescent labels for immunoassay.
  21. Hale Ron L. (Palo Alto CA) Solas Dennis W. (San Francisco CA), Substituted pyridine derivatives.

이 특허를 인용한 특허 (26)

  1. Burba, III, John L.; Hassler, Carl R.; O'Kelley, C. Brock; Lupo, Joseph A.; Pascoe, Joseph R., Apparatus for treating a flow of an aqueous solution containing arsenic.
  2. Christopher B. Buck, Automatic pallet fabrication apparatus and methods.
  3. Kiefer Garry E. ; Simon Jaime ; Garlich Joseph R., Bicyclopol yazamacrocyclophosphonic acid complexes for use as contrast agents.
  4. Takalo,Harri; Rosenberg,Jaana, Biospecific binding reactants labeled with new luminescent lanthanide chelates and their use.
  5. Lamarque, Laurent; Maury, Olivier; Parker, David; Zwier, Jurriaan; Walton, James W.; Bourdolle, Adrien, Complexing agents and corresponding lanthanide complexes.
  6. Burba, John, Composition and process for making the composition.
  7. Witham, Richard Donald; McNew, Edward Bayer; Burba, III, John Leslie, Composition for removing arsenic from aqueous streams.
  8. Burba, III, John L., Composition for treating a fluid.
  9. Kiefer Garry E. ; Bornhop Darryl J., Fluorescent chelates as visual tissue specific imaging agents.
  10. Marx, Jörg; Schumer, Frank; Lischewski, Regina; Zeckert, Kornelia; Böhme, Hans-Joachim; Hennig, Horst, Lanthanide chelates and use thereof in bioanalysis.
  11. Maury, Olivier; Andraud, Chantal; Placide, Virginie; Pitrat, Delphine, Lanthanide complexes comprising at least two betaine groups, which can be used as luminescent markers.
  12. Parker, David; Atkinson, Paul; Kielar, Filip; Boge, Annegret; Sportsman, J. Richard; Gaudet, Elizabeth; Yi, George G., Luminescent lanthanide complexes.
  13. Kwiatkowski Marek,FIX ; Sund Christian,FIX ; Ylikoski Jyrki,FIX ; Mukkala Veli-Matti,FIX ; Hemmila Ilkka,FIX, Metal-chelating 2,6-disubstituted pyridine compounds and their use.
  14. Hemmila Ilkka (Turku FIX) Lovgren Timo (Turku FIX), Modulated homogeneous fluorescence biospecific affinity assay employing fluorescing lanthanide chelates as covalent labe.
  15. Boge, Annegret; Lavis, Luke D.; Sportsman, J. Richard; Hoekstra, Merl F.; Huang, Wei, Molecular modification assays.
  16. Boge, Annegret; Sportsman, J. Richard; Gaudet, Elizabeth; Yi, George G., Molecular modification assays.
  17. Huang,Wei; Hoekstra,Merl F.; Sportsman,J. Richard; Terpetschnig,Ewald A., Molecular modification assays.
  18. Mullinax Thomas Robert ; Cody Margaret R. ; Bobrow Mark N., Neutral enhancement of lanthanides for time resolved fluorescence.
  19. Burba, III, John L.; Oriard, Tim L., Process and apparatus for treating a gas containing a contaminant.
  20. Cable, Robert; Hassler, Carl; Burba, John, Rare earth removal of hydrated and hydroxyl species.
  21. Psaras, Dimitrios; Gao, Yuan; Haneline, Mason; Lupo, Joseph; Landi, Carol, Removal of arsenic from aqueous streams with cerium (IV) oxide compositions.
  22. Hovinen,Jari, Terminating substrates for DNA polymerases.
  23. Qin, Qiu-Ping; Takalo, Harri; Byrnard, Allan Milton; Jakobsen, Kirsten Marie, Thrombin substrate and assay for determining the level of bioactive thrombin in a sample.
  24. Kiefer, Garry E.; Bornhop, Darryl J., Tissue specific fluorescent chelates possessing long wavelength UV excitation.
  25. Hall-Goulle Veronique,CHX, Triboluminescent lanthanide.sup.III complexes.
  26. Witham, Richard Donald; McNew, Edward Bayer; Burba, III, John Leslie, Water purification device for arsenic removal.
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