초록 ▼

A filtration system for handling an array of filter wells which are open at the top and closed by a filter membrane at the bottom. The system includes a manifold chamber defined by side and bottom walls and having a support for the wells which carries the filter membranes above the bottom walls so t

A filtration system for handling an array of filter wells which are open at the top and closed by a filter membrane at the bottom. The system includes a manifold chamber defined by side and bottom walls and having a support for the wells which carries the filter membranes above the bottom walls so that filtrate may be drawn through the membranes. A vacuum fitting is connected to the chamber so that a low pressure source may be applied thereto, and a sealing sheet extends over the wells and having holes aligned with the open tops of the wells so that when the low pressure is applied to the chamber, filtrate may be drawn through the membrane.

대표청구항 ▼

A filtration system for handling 96 well filter plates or filter strips wherein the plates or strips have an array of wells each including a generally cylindrical side wall closed at the bottom by a filter membrane and open at the top comprising a manifold having continuous side and end walls and a

A filtration system for handling 96 well filter plates or filter strips wherein the plates or strips have an array of wells each including a generally cylindrical side wall closed at the bottom by a filter membrane and open at the top comprising a manifold having continuous side and end walls and a bottom wall connected to the side and end walls upwardly of the bottom edges thereof so as to be disposed above a supporting surface when the manifold is placed with lower edges of the side and end walls on the surface, a shoulder in the side and end walls for supporting a plate or strip placed in the manifold, a plurality of supports extending upwardly from the bottom wall for engaging the filter membranes disposed at the bottom of the cylindrical wall of each well when the plate or strip is supported on the shoulder, a first sealing surface in the side and end walls coplanar with the open tops of the cylindrical walls of the wells when the plate or strip is disposed in the manifold and the bottoms of the cylindrical walls are engaged by the supports, a sheet of sealing material disposed on the first sealing surface and engaging the tops of the wells and having means defining openings therein registering with the open tops of the cylindrical walls, said sheet preventing entry of material between said wells, a vacuum hose fitting in one of the side or end walls for connecting a low pressure source to the manifold above the bottom wall, the low pressure source causing the sheet of sealing material to seal about the tops of the cylindrical walls and draw filtrate material in the wells through the filter membrane, an imperforate removable film disposed over the top of the manifold for maintaining a sterile atmosphere in the manifold prior to use, and a second sealing surface in the side and end walls and disposed above the first surface for supporting the imperforate removable film.