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Transdermal delivery device having a rate controlling adhesive 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/00
출원번호 US-0903002 (1986-09-02)
발명자 / 주소
  • Enscore David J. (Sunnyvale CA) Lee Eun S. (Redwood City CA) Yum Su I. (Los Altos CA)
출원인 / 주소
  • Alza Corporation (Palo Alto CA 02)
인용정보 피인용 횟수 : 69  인용 특허 : 10

초록 ▼

A transdermal delivery device having a release-rate controlling-adhesive is disclosed having improved delivery characteristics. The device employs a polyisobutylene/mineral oil adhesive formulation and an ethylene/viny acetate (EVA) drug reservoir formulation. The device is useful in delivering a wi

대표청구항 ▼

A medical device for the transdermal administration of a drug said device conforming to the Rate Controlling Adhesive Relationship and comprising: (a) a drug reservoir comprising a drug dispersed with an ethylene/vinyl acetate copolymer having a vinyl acetate content in the range of about 15-60% by

이 특허에 인용된 특허 (10)

  1. von Bittera Miklos (Leverkusen DEX) Meyer Rolf-Volker (Krefeld DEX), Active compound release systems.
    상세보기
  2. Urquhart John (Palo Alto CA) Chandrasekaran Santosh Kumar (Palo Alto CA) Shaw Jane Elizabeth (Atherton CA), Bandage for transdermally administering scopolamine to prevent nausea.
    상세보기
  3. Higuchi Takeru (Lawrence KS) Hussain Anwar (Lexington KY), Device consisting of copolymer having acetoxy groups for delivering drugs.
    상세보기
  4. Chandrasekaran Santosh K. (Palo Alto CA), Dissolution controlled active agent dispenser.
    상세보기
  5. Ushiyama Keiichi (Osaka JPX) Ichinose Hisashi (Osaka JPX), Drug administration material.
    상세보기
  6. Gerstel Martin S. (Palo Alto CA) Place Virgil A. (Palo Alto CA), Drug delivery device.
    상세보기
  7. Chandrasekaran Santosh Kumar (Palo Alto CA) Urquhart John (Palo Alto CA) Shaw Jane Elizabeth (Atherton CA), Method and therapeutic system for providing chemotherapy transdermally.
    상세보기
  8. Chandrasekaran Santosh K. (Palo Alto CA), Therapeutic system for administering drugs to the skin.
    상세보기
  9. Gale Robert M. (Los Altos CA) Berggren Randall G. (Livermore CA), Transdermal delivery system for delivering nitroglycerin at high transdermal fluxes.
    상세보기
  10. Bondi Joseph V. (Collegeville PA) Loper Alice E. (Harlesyville PA) Cohen Edward M. (Norristown PA), Transdermal system for timolol.
    상세보기

이 특허를 인용한 특허 (69)

  1. Brown,Teletha A.; Osborne,James; Rudella,Michael; Hunt,Brian; Malik,Vinod, Compositions and medical device for transdermal delivery of a drug and methods of making and using same.
    상세보기
  2. Kanios, David P.; Hartwig, Rod; Mantelle, Juan A.; Houze, David W., Compositions and methods for controlling drug loss and delivery in transdermal drug delivery systems.
    상세보기
  3. Kanios, David; Hartwig, Rod, Compositions and methods for controlling the flux of a drug from a transdermal drug delivery systems.
    상세보기
  4. Kanios, David; Hartwig, Rod, Compositions and methods for delivering active agents in transdermal drug delivery systems.
    상세보기
  5. Bozik, Michael E.; Petzinger, Jr., Thomas; Mather, James L.; Archibald, Donald, Compositions and methods for treating amyotrophic lateral sclerosis in responders.
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  6. Bozik, Michael E.; Petzinger, Jr., Thomas; Mather, James L.; Archibald, Donald, Compositions and methods for treating amyotrophic lateral sclerosis in responders.
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  7. Bozik, Michael E.; Dworetzky, Steven, Compositions and methods for treating chronic urticaria.
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  8. Bozik, Michael E; Dworetzky, Steven, Compositions and methods for treating chronic urticaria.
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  9. Bozik, Michael E.; Hebrank, Gregory; Farwell, Wildon; Petzinger, Jr., Thomas; Dworetzky, Steven, Compositions and methods for treating conditions related to increased eosinophils.
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  10. Bozik, Michael E.; Dworetzky, Steven, Compositions and methods for treating plasma cell disorders and B-cell prolymphocytic disorders.
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  11. Bozik, Michael E.; Dworetzky, Steven, Compositions and methods for treating plasma cell disorders and B-cell prolymphocytic disorders.
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  12. Bozik, Michael E.; Gribkoff, Valentin; Petzinger, Jr., Thomas, Compositions and methods of using (R)-pramipexole.
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  13. Bozik, Michael E.; Petzinger, Jr., Thomas; Gribkoff, Valentin, Compositions and methods of using (R)-pramipexole.
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  14. Bozik, Michael E.; Petzinger, Jr., Thomas; Gribkoff, Valentin, Compositions of R(+) and S(−) pramipexole and methods of using the same.
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  15. Bozik, Michael E.; Petzinger, Jr., Thomas; Gribkoff, Valentin, Compositions of R(+) and S(−) pramipexole and methods of using the same.
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  16. Houze, David; Mantelle, Juan; Kanios, David, Dermal composition for controlling drug flux comprising two acrylic adhesive polymers having different functionalities and different solubility parameters.
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  17. Houze, David; Mantelle, Juan; Kanios, David, Dermal composition for controlling drug flux comprising two acrylic adhesive polymers having different functionalities and different solubility parameters.
    상세보기
  18. Kanios, David, Device for transdermal administration of drugs including acrylic based polymers.
    상세보기
  19. Kanios, David, Device for transdermal administration of drugs including acrylic based polymers.
    상세보기
  20. Kanios, David, Device for transdermal administration of drugs including acrylic polymers.
    상세보기
  21. Kanios, David, Device for transdermal administration of drugs including acrylic polymers.
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  22. Kanios, David, Device for transdermal administration of drugs including acrylic polymers.
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  23. Yunwa W. Cheung ; Martin J. Guest ; William R. Van Volkenburgh, Elastic films made from alpha-olefin/vinyl aromatic and/or aliphatic or cycloaliphatic vinyl or vinylidene interpolymers.
    상세보기
  24. Miller, II, Kenneth J.; Govil, Sharad K.; Bhatia, Kuljit Singh, Fentanyl suspension-based silicone adhesive formulations and devices for transdermal delivery of fentanyl.
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  25. Miller, II, Kenneth J.; Govil, Sharad K.; Bhatia, Kuljit Singh, Fentanyl suspension-based silicone adhesive formulations and devices for transdermal delivery of fentanyl.
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  26. Simon John G. ; Wisnosky Carl J. ; McLaughlin Paul D. ; Joshi Sharad ; Felice Leo C. ; Coulter Christopher C., Fluidly expandable urethral plug assembly which receives fluid from an external source and method for controlling urina.
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  27. Nakamura Katsuhiro,JPX ; Koga Nobuyuki,JPX, Formulation for percutaneous administration for treating disturbance in micturition.
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  28. Gale, Robert M.; Nelson, Melinda K.; Cormier, Michel J. N.; Gupta, Suneel K.; Campbell, Patricia S., Formulations for the administration of fluoxetine.
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  29. Gale,Robert M.; Nelson,Melinda K.; Cormier,Michel J. N.; Gupta,Suneel K.; Campbell,Patricia S., Formulations for the administration of fluoxetine.
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  30. van Osdol, William W.; Crisologo, Nieves M.; Yum, Su Il, Formulations for the transdermal administration of fenoldopam.
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  31. van Osdol, William W.; Crisologo, Nieves M.; Yum, Su Il, Formulations for the transdermal administration of fenoldopam.
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  32. Xu, Bai, High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances.
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  33. Xu, Bai, High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances.
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  34. Xu, Bai, High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances.
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  35. Reder, Robert F.; Goldenheim, Paul D.; Kaiko, Robert F., Method of providing sustained analgesia with buprenorphine.
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  36. Reder, Robert F.; Kaiko, Robert F.; Goldenheim, Paul D., Method of providing sustained analgesia with buprenorphine.
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  37. Reder, Robert F.; Kaiko, Robert F.; Goldenheim, Paul D., Method of providing sustained analgesia with buprenorphine.
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  38. Reder, Robert F.; Kaiko, Robert F.; Goldenheim, Paul D., Method of providing sustained analgesia with buprenorpine.
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  39. Ron, Eyal S.; Langer, Robert S.; Crowley, Jr., William F., Methods and devices for the sustained release of multiple drugs.
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  40. Ron, Eyal S.; Langer, Robert S.; Crowley, Jr., William F., Methods and devices for the sustained release of multiple drugs.
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  41. Ron, Eyal S.; Langer, Robert S.; Crowley, Jr., William F., Methods and devices for the sustained release of multiple drugs.
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  42. Ron, Eyal S.; Langer, Robert S.; Crowley, Jr., William F., Methods and devices for the sustained release of multiple drugs.
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  43. Robert Martin Gale, Methods for transdermal drug administration.
    상세보기
  44. Bozik, Michael E.; Petzinger, Jr., Thomas; Gribkoff, Valentin, Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same.
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  45. Cormier Michel J. N. ; Daddona Peter E. ; Johnson Juanita A., Reduction of skin reactions caused by transdermal drug delivery.
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  46. Armstrong Robert Bruce ; Oda Hidemasa, Self purging EVOH compositions, and methods.
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  47. Chen, Weirong; Humora, Michael; Kwok, Daw-Iong Albert; Kiesman, William F.; Irdam, Erwin Ayandra, Synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds.
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  49. Raje, Prasad; Gadikota, Rajendrakumar Reddy; Chen, Jian-Xie; Lapina, Olga V.; McCall, John M., Synthesis of chirally purified substituted benzothiazole diamines.
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  50. Raje, Prasad; Gadikota, Rajendrakumar Reddy; Chen, Jian-Xie; Lapina, Olga V.; McCall, John M., Synthesis of chirally purified substituted benzothiazole diamines.
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  51. Yum, Su Il; Theeuwes, Felix, Transdermal delivery system for sufentanil.
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  52. Yum, Su Il; Theeuwes, Felix, Transdermal delivery system for sufentanil.
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  53. Stefano, Francisco Jose Evaristo; Scasso, Alejandro Fabio, Transdermal delivery system with two superimposed adhesive layers having different affinities to the active substance comprised.
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  54. Yum, Su II; Kwon, Sung Yun; Song, Xiaoping; Brown, James E., Transdermal delivery systems.
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  56. Yum, Su Il; Theeuwes, Felix, Transdermal delivery systems.
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  57. Watanabe, Tyler; Gale, Robert M., Transdermal drug delivery device package with improved drug stability.
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  58. Mantelle, Juan, Transdermal estrogen device and delivery.
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  62. Deshmukh, Abhijit Mukund; Dixit, Akhilesh; Kumar, Prasanna; Bindra, Vikram, Transdermal therapeutic system for extended dosing of pramipexole in treating neurological disorders.
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  63. Gale, Robert M., Transparent transdermal nicotine delivery devices.
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  64. Gale, Robert M., Transparent transdermal nicotine delivery devices.
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  67. Gale, Robert M., Transparent transdermal nicotine delivery devices.
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  68. Simon John G. ; McLaughlin Paul D. ; Felice Leo C. ; Joshi Sharad ; Syed Azhar ; Tartacower Richelle ; O'Keefe Jonathan, Urethral plug having adhesive for enhanced sealing capabilities and method of using said plug.
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  69. Bond, Richard A.; Glass, Mitchell, Use of beta-adrenergic inverse agonists for smoking cessation.
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