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Method for transporting substances into living cells and tissues and apparatus therefor 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12N-015/00
  • C12N-015/89
출원번호 US-0670771 (1984-11-13)
발명자 / 주소
  • Sanford John C. (Geneva NY) Wolf Edward D. (Ithaca NY) Allen Nelson K. (Newfield NY)
출원인 / 주소
  • Cornell Research Foundation, Inc. (Ithaca NY 02)
인용정보 피인용 횟수 : 571  인용 특허 : 4

초록 ▼

Inert or biologically active particles are propelled at cells at a speed whereby the particles penetrate the surface of the cells and become incorporated into the interior of the cells. The process can be used to mark cells or tissue or to biochemically affect tissues or tissue in situ as well as si

대표청구항 ▼

A method for introducing particles into cells comprising accelerating particles having a diameter sufficiently small to penetrate and be retained in a preselected cell without killing the cell, and propelling said particles at said cells whereby said particles penetrate the surface of said cells and

이 특허에 인용된 특허 (4)

  1. Hengesbach Robert W. (7886 Munson Rd. Mentor OH 44060), Aspirator probe for sand blasting apparatus.
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  2. Nusser Alban (Freising DEX), Device for inking an electrostatic charge image with toner particles.
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  4. Stevenson David J. (36 Sandpiper Rd. Enfield CT 06082) Domian Robert E. (Somers CT), Self-defense spray device.
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이 특허를 인용한 특허 (571)

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  294. Lundquist, Ronald C.; Walters, David A., Method for preparing fertile transgenic corn plants.
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  296. Cahoon, Edgar B.; Hitz, William D.; Ripp, Kevin G., Method for the production of calendic acid, a fatty acid containing delta 8,10,12 conjugated double bonds and related fatty acids having a modification at the delta 9 position.
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  300. Paul Christou ; Tameria L. Ford ; Matt Kofron, Method of creating a transformed rice plant.
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  308. Durrett, Timothy; Ohlrogge, John; Pollard, Michael, Method to produce acetyldiacylglycerols (ac-TAGs) by expression of an acetyltransferase gene isolated from Euonymus alatus (burning bush).
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  309. Burghardt Wittig ; Matthias Schroff DE, Method to separate cells that have been modified with superparamagnetic particles by ballistic transfer.
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  310. Gupta, Anand, Methods and apparatus for forming photovoltaic cells using electrospray.
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  311. Walker, Keith A.; Knuth, Mark E.; Fong, Noel M.; Beetham, Peter R., Methods and compositions for producing squalene using yeast.
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  312. Conkling,Mark A.; Song,Wen; Mendu,Nandini, Methods and compositions for protein production in tobacco plants with reduced nicotine.
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  315. Singh, Ajay Pratap; Srivastava, Sanjeev; Singh, Seema, Methods and compositions for the diagnosis, classification, and treatment of cancer.
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  321. Reed, Eddie; Samant, Lalita; Samant, Rajeev, Methods and compositions for the treatment of cancer.
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  324. Dzekunov, Sergey; Chopas, Nicholas; Li, Linhong, Methods and devices related to a regulated flow electroporation chamber.
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  326. D'Halluin, Kathleen; Dittgen, Jan; Jansens, Stefan; Meulewaeter, Frank; Weterings, Koen; Moser, Hal; Wilde, Thomas; Hain, Ruediger; Bickers, Udo; Trolinder, Linda; Henniger, Gary, Methods and means to modify a plant genome.
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  525. Koziel, Michael; Desai, Nalini; Pace, Gary M.; Suttie, Jan; Carozzi, Nadine; Boyce, Cindy; Dawson, John L.; Dunder, Erik; Wright, Martha; Launis, Karen; Rothstein, Steven J.; Lewis, Kelly; Warren, Gr, Transgenic maize seed and method for controlling insect pests.
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  527. Coruzzi, Gloria; Gutierrez, Rodrigo A.; Nero, Damion C., Transgenic plants expressing GLK1 and CCA1 having increased nitrogen assimilation capacity.
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  528. Hayes, Alec J.; Kudithipudi, Chengalrayan; van der Hoeven, Rutger S., Transgenic plants modified for reduced cadmium transport, derivative products, and related methods.
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  533. Aldwinckle Herbert S. ; Norelli John L., Transgenic pomaceous fruit with fire blight resistance.
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  544. Weiner, David B.; Kutzler, Michele, Vaccines and immunotherapeutics using codon optimized IL-15 and methods for using the same.
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  545. Weiner, David B; Kutzler, Michele, Vaccines and immunotherapeutics using codon-optimized IL-15 and methods for using the same.
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  547. Kadurugamuwa, Jagath L.; Beveridge, Terry J., Vaccines and pharmaceutical compositions using membrane vesicles of microorganisms, and methods for preparing same.
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  548. Weiner, David B; Yan, Jian, Vaccines for human papilloma virus and methods for using the same.
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  550. Levinson, Arnold I.; Calarota, Sandra; Weiner, David B.; Otero, Miguel, Vaccines for suppressing IgE-mediated allergic disease and methods for using the same.
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  558. Thomason, Arlen; Liu, Benxian, Vectors and recombinant host cells comprising nucleic acid molecules encoding Fibroblast Growth Factor-like polypeptides.
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  561. Jamieson, Andrew; Li, Guofu, Zinc finger proteins for DNA binding and gene regulation in plants.
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  562. Jamieson, Andrew; Li, Guofu, Zinc finger proteins for DNA binding and gene regulation in plants.
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  564. Jamieson,Andrew; Li,Guofu, Zinc finger proteins for DNA binding and gene regulation in plants.
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  565. Fader, Gary Michael, cDNA sequences from plants that encode activities associated with isoflavone biosynthesis.
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  566. Weiner, David B.; Yan, Jian, hTERT sequences and methods for using the same.
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  567. Macklin,Michael D.; Fuller,Deborah L., immunization.
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  569. Mukerji, Pradip; Das, Tapas; Huang, Yung-Sheng; Thurmond, Jennifer; Pereira, Suzette L., Δ-6 desaturase and uses thereof.
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  570. Mukerji, Pradip; Huang, Yung-Sheng; Leonard, Amanda E.; Pereira, Suzette L.; Thurmond, Jennifer M., Δ6-desaturase genes and uses thereof.
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  571. Pereira, Suzette; Das, Tapas; Krishnan, Padmavathy; Mukerji, Pradip, Δ9-elongase for production of polyunsaturated fatty acid-enriched oils.
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