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Prosthesis for promotion of nerve regeneration 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61B-017/08
  • A61F-002/04
출원번호 US-0327530 (1989-03-23)
발명자 / 주소
  • Yannas Ioannis V. (Newton MA) Orgill Dennis P. (Belmont MA) Loree
  • II Howard M. (Cambridge MA) Kirk James F. (Cambridge MA) Chang Albert S. P. (Foster City MA) Mikic Borivoje B. (Cambridge MA) Kraru
출원인 / 주소
  • Massachusetts Institute of Technologh (Cambridge MA 02)
인용정보 피인용 횟수 : 45  인용 특허 : 1

초록

A method for producing a biodegradable polymer having a preferentially oriented pore structure and a method for using the polymer to regenerate damaged nerve tissue is disclosed. The preferentially oriented pores are produced by an axial freezing process and serve to promote proper vascularation and

대표청구항

A prosthetic device for axonal regeneration of nerve tissue, said device comprising a porous, biodegradable template with preferentially oriented pores, made by a method comprising the steps of: a. introducing an aqueous suspension of collagen-glycosaminoglycan into a tubular mold; b. lowering the t

이 특허에 인용된 특허 (1)

  1. Yannas Ioannis V. (Newton Center MA) Burke John F. (Belmont MA) Stasikelis Peter J. (Houston TX), Method for preserving porosity in porous materials.

이 특허를 인용한 특허 (45)

  1. Blott, Patrick Lewis; Greener, Bryan; Hartwell, Edward Yerbury; Nicolini, Derek; Walker, Tina Michelle; Lee-Webb, Julian, Apparatus for aspirating, irrigating and cleansing wounds.
  2. Blott, Patrick Lewis; Greener, Bryan; Hartwell, Edward Yerbury; Walker, Tina Michelle; Nicolini, Derek; Lee-Webb, Julian, Apparatus for aspirating, irrigating and cleansing wounds.
  3. Blott, Patrick Lewis; Greener, Bryan; Hartwell, Edward Yerbury; Walker, Tina Michelle; Nicolini, Derek; Lee-Webb, Julian, Apparatus for aspirating, irrigating and cleansing wounds.
  4. Blott, Patrick Lewis; Greener, Bryan; Hartwell, Edward Yerbury; Walker, Tina Michelle; Nicolini, Derek; Lee-Webb, Julian, Apparatus for aspirating, irrigating and cleansing wounds.
  5. Murray, Martha M.; Murray, Michael F.; Marler, Jennifer, Biologic replacement for fibrin clot.
  6. Murray, Martha M.; Murray, Michael F.; Marler, Jennifer, Biologic replacement for fibrin clot.
  7. Murray, Martha M.; Murray, Michael F.; Marler, Jennifer, Biologic replacement for fibrin clot.
  8. Masters, David B.; Berg, Eric Peter, Biomatrix structural containment and fixation systems and methods of use thereof.
  9. Murray, Martha M., Collagen scaffolds.
  10. Masters, David B.; Berg, Eric P., Encapsulated or coated stent systems.
  11. Weston, Richard Scott, Flexible reduced pressure treatment appliance.
  12. Weston, Richard Scott, Flexible reduced pressure treatment appliance.
  13. Weston, Richard Scott, Flexible reduced pressure treatment appliance.
  14. Weston, Richard Scott, Flexible reduced pressure treatment appliance.
  15. Ingram, Ronald T.; Patel, Jignesh B.; Pryor, Timothy J., Flowable wound matrix and its preparation and use.
  16. Ingram, Ronald T.; Patel, Jignesh B.; Pryor, Timothy J., Flowable wound matrix and its preparation and use.
  17. Simmoteit,Robert; Fisher geb. Schoof,Heike, Implant and process for producing it.
  18. Blott, Patrick Lewis; Greener, Bryan; Hartwell, Edward Yerbury; Walker, Tina Michelle; Nicolini, Derek; Lee-Webb, Julian, In-situ wound cleansing apparatus.
  19. Tuch,Ronald J., Medical device for delivering a therapeutic agent and method of preparation.
  20. Berg, Eric P.; Dinh, Thomas Q., Medical device for delivering a therapeutic substance and method therefor.
  21. Dinh Thomas Q. ; Wolff Rodney G. ; Berg Eric P., Medical device for delivering a therapeutic substance and method therefor.
  22. Thomas Q. Dinh ; Rodney G. Wolff ; Eric P. Berg, Medical device for delivering a therapeutic substance and method therefor.
  23. Berg, Eric P.; Tuch, Ronald J.; Dror, Michael; Wolff, Rodney G., Medical devices for delivering a therapeutic agent and method of preparation.
  24. Berg,Eric P.; Tuch,Ronald J.; Dror,Michael; Wolff,Rodney G., Medical devices for delivering a therapeutic agent and method of preparation.
  25. Langer, Robert S.; Saigal, Rajiv; Teng, Yang; Woodard, Eric, Medical devices for use in the surgical treatment of hyperproliferative diseases affecting the spinal cord.
  26. Robert T. Tranquillo ; Stefano Guido IT, Method of nerve regeneration using biopolymer rods with oriented fibrils.
  27. Langer, Robert S.; Saigal, Rajiv; Teng, Yang, Methods and compositions for the treatment of open and closed wound spinal cord injuries.
  28. Langer, Robert S.; Saigal, Rajiv; Teng, Yang, Methods and compositions for the treatment of open and closed wound spinal cord injuries.
  29. Langer, Robert S.; Saigal, Rajiv; Teng, Yang, Methods and compositions for the treatment of open and closed wound spinal cord injuries.
  30. Langer, Robert S.; Saigal, Rajiv; Teng, Yang, Methods and compositions for the treatment of open and closed wound spinal cord injuries.
  31. Murray, Martha M., Methods and products for tissue repair.
  32. Murray, Martha M., Methods and products for tissue repair.
  33. Li Shu-Tung (Oakland NJ), Multi-layered, semi-permeable conduit for nerve regeneration comprised of type 1 collagen, its method of manufacture and.
  34. Hadlock Theresa Anne ; Sundback Cathryn, Multi-lumen polymeric guidance channel and method of manufacturing a polymeric prosthesis.
  35. Mares-Guia Marcos, Non-immunogenic, biocompatible macromolecular membrane compositions, and methods for making them.
  36. Masters, David B., Protein biomaterial and biocoacervate vessel graft systems and methods of making and using thereof.
  37. Masters, David B.; Berg, Eric P., Protein biomaterials and biocoacervates and methods of making and using thereof.
  38. Masters, David B.; Berg, Eric P., Protein biomaterials and biocoacervates and methods of making and using thereof.
  39. Masters, David B., Protein matrix materials, devices and methods of making and using thereof.
  40. Weston, Richard Scott, Reduced pressure treatment system.
  41. Weston, Richard Scott, Reduced pressure treatment system.
  42. Blott, Patrick Lewis; Greener, Bryan; Hartwell, Edward Yerbury; Walker, Tina Michelle; Lee-Webb, Julian; Nicolini, Derek; Green, Clare; Martin, Robin Paul, Wound cleansing apparatus.
  43. Blott, Patrick Lewis; Greener, Bryan; Hartwell, Edward Yerbury; Walker, Tina Michelle; Lee-Webb, Julian; Nicolini, Derek; Green, Clare; Martin, Robin Paul, Wound cleansing apparatus.
  44. Blott, Patrick Lewis; Greener, Bryan; Hartwell, Edward Yerbury; Lee-Webb, Julian; Nicolini, Derek; Green, Clare; Martin, Robin Paul; Walker, Tina Michelle, Wound cleansing apparatus with heat.
  45. Masters, David B.; Berg, Eric P., Wound treatments with crosslinked protein amorphous biomaterials.
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