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Polymers containing acetal, carboxy-acetal, ortho ester and carboxyortho ester linkages 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C08G-063/06
  • C08G-067/00
출원번호 US-0234806 (1988-08-22)
발명자 / 주소
  • Heller Jorge (Woodside CA) Ng Steve Y. W. (San Francisco CA) Penhale Donald W. H. (Menlo Park CA)
출원인 / 주소
  • Pharmaceutical Delivery Systems, Inc. (Menlo Park CA 02)
인용정보 피인용 횟수 : 35  인용 특허 : 7

초록

Biodegradable polymers that are useful for making biodegradable sustained release agent dispensers and which contain acetal, carboxy-acetal, ortho ester and/or carboxy-ortho ester linkages.

대표청구항

A linear or crosslinked biodegradable polymer containing a combination of the following mer units: [Figure] [Figure] [Figure] and [Figure] wherein X is a quadrivalent organic grouping, A and B may be the same or different and are selected from the group consisting of hydrogen, and lower alkyl, and R

이 특허에 인용된 특허 (7)

  1. Sparer, Randall V.; Pogany, Stefano A., Bioerodible poly(ortho ester) thermoplastic elastomer from diketene diacetal.
  2. Choi ; Nam Sok ; Heller ; Jorge, Drug delivery devices manufactured from poly(orthoesters) and poly(orthocarbonates).
  3. Manser Gerald E. (Folsom CA) Fletcher Richard W. (Fair Oaks CA), Nitramine oxetanes and polyethers formed therefrom.
  4. Choi Nam S. (Seoul CA KRX) Heller Jorge (Palo Alto CA), Novel orthoester polymers and orthocarbonate polymers.
  5. Heller Jorge (Palo Alto CA) Helwing Robert F. (Sunnyvale CA) Penhale Donald W. (Cupertino CA), Polymers of di- (and higher functionality) ketene acetals and polyols.
  6. VON DER Eltz Hans-Ulrich (Frankfurt am Main DEX), Process for the continuous dyeing of wool.
  7. Choi ; Nam S. ; Heller ; Jorge, Structured orthoester and orthocarbonate drug delivery devices.

이 특허를 인용한 특허 (35)

  1. Hobot, Christopher M.; Benz, Michael E.; Hildebrand, Keith R.; Pudil, Bryant J., Baclofen formulation in a polyorthoester carrier.
  2. Hobot, Christopher M.; Benz, Michael E.; Hildebrand, Keith R.; Pudil, Bryant J., Benzodiazepine formulation in a polyorthoester carrier.
  3. Ng, Steven Y.; Heller, Jorge, Bioerodible poly (orthoesters) from dioxolane-based diketene acetals.
  4. Heller,Jorge; Ng,Steven Y., Bioerodible poly(ortho esters) from dioxane-based di(ketene acetals), and block copolymers containing them.
  5. Ng, Steven Y.; Heller, Jorge, Bioerodible polyorthoesters containing amine groups.
  6. Ng, Steven Y.; Heller, Jorge, Bioerodible polyorthoesters from dioxolane-based diketene acetals.
  7. Ng, Steven Y.; Heller, Jorge, Block copolymers based on poly(ortho esters) containing amine groups.
  8. Ng, Steven Y.; Heller, Jorge, Block copolymers based on poly(ortho esters) containing amine groups.
  9. Hobot, Christopher M.; Benz, Michael E.; Hildebrand, Keith R.; Pudil, Bryant J., Bupivacaine formulation in a polyorthoester carrier.
  10. Pacetti, Stephen D.; Hossainy, Syed F. A.; Tang, Yiwen; Tung, Andrew C.; Glauser, Thierry, Coatings for drug delivery devices having gradient of hydration.
  11. Ottoboni, Thomas B.; Schillinger, Lee Ann Lynn, Compositions of a polyorthoester and an aprotic solvent.
  12. Ottoboni, Thomas B.; Schillinger, Lee Ann Lynn, Compositions of a polyorthoester and an aprotic solvent.
  13. Ottoboni, Thomas B.; Schillinger, Lee Ann Lynn; Niemann, Joseph, Compositions of a polyorthoester and an aprotic solvent.
  14. Ottoboni, Thomas B.; Schillinger, Lee Ann Lynn; Niemann, Joseph, Compositions of a polyorthoester and an aprotic solvent.
  15. Brocchini,Stephen J.; Heller,Jorge; Tomlinson,Ryan; Duncan,Ruth; Garrett,Shane; Klee,Marcus M., Degradable polyacetal polymers.
  16. Rozema,David B.; Wakefield,Darren, Labile linkage for compound delivery to a cell.
  17. Ottoboni, Thomas B.; Girotti, Lee Ann Lynn, Long-acting polymeric delivery systems.
  18. Ottoboni, Thomas B.; Girotti, Lee Ann Lynn, Long-acting polymeric delivery systems.
  19. Ottoboni, Thomas B.; Girotti, Lee Ann Lynn, Long-acting polymeric delivery systems.
  20. Ottoboni, Thomas B.; Girotti, Lee Ann Lynn, Long-acting polymeric delivery systems.
  21. Kozlowski, Antoni, Method for preparing water-soluble polymer derivatives bearing a terminal carboxylic acid.
  22. Kozlowski, Antoni, Method for preparing water-soluble polymer derivatives bearing a terminal carboxylic acid.
  23. Kozlowski, Antoni, Method for preparing water-soluble polymer derivatives bearing a terminal carboxylic acid.
  24. Kozlowski, Antoni, Method for preparing water-soluble polymer derivatives bearing an N-succinimidyl ester.
  25. Pacetti, Stephen D.; Hossainy, Syed F. A.; Tang, Yiwen; Tung, Andrew C.; Glauser, Thierry, Methods for fabricating coatings for drug delivery devices having gradient of hydration.
  26. Pacetti, Stephen D.; Hossainy, Syed F. A.; Tang, Yiwen; Tung, Andrew C.; Glauser, Thierry, Methods for fabricating coatings for drug delivery devices having gradient of hydration.
  27. Kozlowski, Antoni, Orthoester compound.
  28. Heller Jorge ; Ng Steven Y., PEG-POE, PEG-POE-PEG, and POE-PEG-POE block copolymers.
  29. Alkatout, Julie A.; Benz, Michael Eric; Sparer, Randall V., Poly(orthoester) polymers, and methods of making and using same.
  30. Alkatout, Julie A.; Benz, Michael Eric; Sparer, Randall V., Poly(orthoester) polymers, and methods of making and using same.
  31. Heller Jorge ; Ng Steven Y., Polymers with controlled physical state and bioerodibility.
  32. Chen, Guohua; Priebe, David T., Short duration depot formulations.
  33. Evans,James A.; Miranda,Leandro E.; Kirk,James P., System and method for controlling growth of aquatic plants utilizing bio-eroding means implanted in triploid grass carp.
  34. Asgharian, Bahram; Chowhan, Masood A.; Wax, Martin B., Water insoluble polymer matrix for drug delivery.
  35. Evans, James A.; Miranda, Leandro E.; Kirk, James P., “Implant and forget” mechanism to interact with biota, in particular fauna that may outgrow available habitat and method of use thereof.
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