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Inductive collagen-based bone repair preparations 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-035/32
  • A61L-027/00
출원번호 US-0816268 (1986-01-06)
발명자 / 주소
  • Nathan Ranga (Newark) Seyedin Saeid (Mountain View) Piez Karl (Menlo Park) Bentz Hanne (Palo Alto CA)
출원인 / 주소
  • Collagen Corporation (Palo Alto CA 02)
인용정보 피인용 횟수 : 66  인용 특허 : 7

초록 ▼

A composition suitable for inductive bone implants is disclosed. The composition comprises a purified form of osteogenic factor in admixture with an carrier having a percentage of mineral carrier. The resulting implants are sufficiently hypoimmunogenic to be effective when implanted in xenogeneic ho

대표청구항 ▼

A method of effecting bone repair in vertebrates in need of such treatment which comprises implanting into a bone defect a hypoimmunogenic composition which comprises an osteoinductively effective amount of a protein osteoinductive factor (OFE) derived from bone, which OFE is sufficiently pure to be

이 특허에 인용된 특허 (7)

  1. Urist Marshall R. (Pacific Palisade CA), Biodegradable porous ceramic delivery system for bone morphogenetic protein.
    상세보기
  2. Jefferies Steven R. (5802 Leith Walk Baltimore MD 21239), Bone graft material for osseous defects and method of making same.
    상세보기
  3. Urist Marshall R. (Pacific Palisade CA), Bone morphogenetic protein process.
    상세보기
  4. Huguenin Raymond (Preles CHX) Kuechli Gottfried (Bienne CHX), Method of manufacturing piezoelectric resonator components.
    상세보기
  5. Smestad Thomas L. (San Jose CA), Nonstress-bearing implantable bone prosthesis.
    상세보기
  6. Glowacki Julianne (Jamaica Plain MA) Pharriss Bruce B. (Palo Alto CA), Osteogenic composition and method.
    상세보기
  7. Seyedin Saeid (Mt. View CA) Thomas Thomas (Palo Alto CA), Partially purified osteogenic factor and process for preparing same from demineralized bone.
    상세보기

이 특허를 인용한 특허 (66)

  1. Trieu,Hai H.; Chaffin,Kimberly A., Bioactive nanocomposites and methods for their use.
    상세보기
  2. Chow, David; Geremakis, Perry; Martz, Erik O.; Hochschuler, Stephen Howard; Rosenthal, Daniel E.; Annunziato, Steven; Johnston, Larry C., Bone fasteners and method for stabilizing vertebral bone facets using the bone fasteners.
    상세보기
  3. Chow, David; Geremakis, Perry; Martz, Erik O.; Hochschuler, Stephen Howard; Rosenthal, Daniel E.; Annunziato, Steven; Johnston, Larry C., Bone fasteners and method for stabilizing vertebral bone facets using the bone fasteners.
    상세보기
  4. Cook, Russell L.; Antone, Duraid S., Bone graft materials and methods.
    상세보기
  5. Cook, Russell L.; Antone, Duraid S., Bone graft materials and methods.
    상세보기
  6. Thorne, Kevin J., Bone growth particles and osteoinductive composition thereof.
    상세보기
  7. Thorne, Kevin J., Bone growth particles and osteoinductive composition thereof.
    상세보기
  8. Hair, Gregory A.; Boden, Scott D., Bone mineralization proteins, DNA, vectors expression systems.
    상세보기
  9. Gregory A. Hair ; Scott D. Boden, Bone mineralization proteins, DNA, vectors, expression systems.
    상세보기
  10. Hair Gregory A. ; Boden Scott D., Bone mineralization proteins, DNA, vectors, expression systems.
    상세보기
  11. Hair, Gregory A.; Boden, Scott D., Bone mineralization proteins, DNA, vectors, expression systems.
    상세보기
  12. Johnson Wesley D. ; Johnson James R. ; Marx Jeffrey G., Bone substitute materials.
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  13. Johnson James R. ; Marx Jeffrey G. ; Johnson Wesley D., Bone substitutes.
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  14. Johnson, James R.; Marx, Jeffrey G.; Johnson, Wesley D., Bone substitutes.
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  15. Akella, Rama; Garrett, Ian Ross; Wen, Hai Bo; Li, Shuliang; Acker, Dean M.; Wilhelm, Nichole, Bone void fillers.
    상세보기
  16. Wang, Shanshan, Composite collagen sponge and preparation method thereof.
    상세보기
  17. Thorne, Kevin J., Composition and process for bone growth and repair.
    상세보기
  18. Baird, Andrew; Gonzalez, Ana Maria; Logan, Ann; Berry, Martin, Compositions and methods for delivery of agents for neuronal regeneration and survival.
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  19. Shimp, Lawrence A.; Behnam, Keyvan; Wei, Guobao; Selim, Abdulhafez A., Compositions and methods for promoting bone formation.
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  20. Atkinson, Brent; Benedict, James J., Compositions for regeneration and repair of cartilage lesions.
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  21. Chen Charles C. ; Jefferies Steven R., Compositions with enhanced osteogenic potential, methods for making the same and uses thereof.
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  22. Jefferies Steven R., Delayed drug delivery system.
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  23. Evans, Douglas G.; Goldman, Scott M.; Kronengold, Russell T., Devices and methods for treating defects in the tissue of a living being.
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  24. Evans, Douglas G; Goldman, Scott M.; Kronengold, Russell T., Devices and methods for treating defects in the tissue of a living being.
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  25. Evans, Douglas G; Goldman, Scott M.; Kronengold, Russell T., Devices and methods for treating defects in the tissue of a living being.
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  26. Evans, Douglas G; Goldman, Scott M.; Kronengold, Russell T., Devices and methods for treating defects in the tissue of a living being.
    상세보기
  27. Evans, Douglas G; Goldman, Scott M.; Kronengold, Russell T., Devices and methods for treating defects in the tissue of a living being.
    상세보기
  28. Evans, Douglas G; Goldman, Scott M.; Kronengold, Russell T., Devices and methods for treating defects in the tissue of a living being.
    상세보기
  29. Bonadio Jeffrey ; Goldstein Steven A., Gene transfer into bone cells and tissues.
    상세보기
  30. Morris, John W.; Knaack, David A.; Shimp, Lawrence A.; Behnam, Keyvan; Skinner, Robert P.; Betz, Randal R., Hemostatic bone graft.
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  31. McKay, William F., Highly mineralized osteogenic sponge compositions and uses thereof.
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  32. McKay, William F., Highly-mineralized osteogenic sponge compositions and uses thereof.
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  33. McKay, William F., Highly-mineralized osteogenic sponge compositions, and uses thereof.
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  34. Beertsen Wouter (Santpoort Zuid NLX) van den Bos Theo (Zeist NLX), Implant materials having a phosphatase and an organophosphorus compound for in vivo mineralization of bone.
    상세보기
  35. Benedict, James J.; Damien, Christopher J., Implantable putty material.
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  36. Benedict, James J.; Damien, Christopher J., Implantable putty material.
    상세보기
  37. Goldstein Steven A. ; Bonadio Jeffrey, In vivo gene transfer methods for wound healing.
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  38. Orly Isabelle (Lyons FRX) Huc Alain (Ste Foy les Lyon FRX), Injectable compositions containing collagen microcapsules.
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  39. Lloyd Wolfinbarger, Jr., Method and process for the production of collagen preparations from invertebrate marine animals and compositions thereof.
    상세보기
  40. Wolfinbarger, Jr., Lloyd, Method and process for the production of collagen preparations from invertebrate marine animals and compositions thereof.
    상세보기
  41. Morris, John W.; Shimp, Lawrence A.; Petersen, Kenneth C.; Manrique, Albert; Kaes, David; Scarborough, Nelson; Dowd, Michael, Method of making demineralized bone particles.
    상세보기
  42. Morris, John W.; Shimp, Lawrence A.; Petersen, Kenneth C.; Manrique, Albert; Kaes, David; Scarborough, Nelson; Dowd, Michael, Method of making demineralized bone particles.
    상세보기
  43. Bonadio Jeffrey ; Goldstein Steven A., Methods and compositions for multiple gene transfer into bone cells.
    상세보기
  44. Bonadio, Jeffrey; Yin, Wushan, Methods of using latent TGF-β binding proteins.
    상세보기
  45. McKay, William F.; Scifert, Jeffrey L., Multi-purpose medical implant devices.
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  46. McKay, William F., Osteogenic compositions containing a coloring agent.
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  47. McKay, William F., Osteogenic compositions containing a coloring agent.
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  48. McKay, William F.; Boden, Scott D.; Beals, Neil B., Osteogenic implants with combined implant materials and methods for same.
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  49. McKay, William F.; Boden, Scott D.; Beals, Neil B., Osteogenic implants with combined implant materials and methods for same.
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  50. McKay, William F.; Boden, Scott D.; Beals, Neil B., Osteogenic implants with combined implant materials and methods for same.
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  51. McKay, William F.; Boden, Scott D.; Beals, Neil, Osteogenic implants with combined implant materials, and materials and methods for same.
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  52. Damien Christopher J. (Denver CO) Benedict James J. (Golden CO) Poser James W. (Lawrenceville NJ), Osteogenic product and process.
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  53. Manrique, Albert; Edwards, Jean T.; Scarborough, Nelson L.; Boden, Scott D.; Traianedes, Kathy; Shimp, Lawrence A.; Russell, James L., Osteoimplant and method of making same.
    상세보기
  54. Manrique, Albert; Edwards, Jean T.; Scarborough, Nelson L.; Boden, Scott D.; Traianedes, Kathy; Shimp, Lawrence A.; Russell, James L., Osteoimplant and method of making same.
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  55. Manrique, Albert; Edwards, Jean T.; Scarborough, Nelson L.; Boden, Scott D.; Traianedes, Kathy; Shimp, Lawrence A.; Russell, James L., Osteoimplant and method of making same.
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  56. Betz, Randal R.; Boden, Scott D.; Clark, Christine; Forsyth, Nanette; Morris, John W.; Traianedes, Kathy, Osteoimplants and methods for their manufacture.
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  57. Betz, Randal R.; Boden, Scott D.; Clark, Christine; Forsyth, Nanette; Morris, John W.; Traianedes, Kathy, Osteoimplants and methods for their manufacture.
    상세보기
  58. Ito Michio (Nagano JPX), Osteoinduction substance, method of manufacturing the same, and bone filling material including the same.
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  59. Ismailoglu, Ali; Vizesi, Frank; Chen, Sung-Ching; Lai, Po-Hung; Chien, Kehsin, Osteoinductive bone graft substitute.
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  60. Marx, Jeffrey G.; Heckendorf, Bradley R.; Johnson, James R.; Venarsky, John Jeffrey, Process for producing rigid reticulated articles.
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  61. Thorne, Kevin; Akella, Rama, Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue.
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  62. Bonadio Jeffrey ; Yin Wushan, Recombinant production of latent TGF-beta binding protein-3 (LTBP-3).
    상세보기
  63. Bonutti,Peter M., Scaffold and method for implanting cells.
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  64. Lawin Timothy P. ; Klein Dean, Tissue injectable composition and method of use.
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  65. Scarborough, Nelson L.; Gadaleta, Sergio J.; Keas, David; Manrique, Albert, Volume maintaining osteoinductive/osteoconductive compositions.
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  66. Scarborough, Nelson L.; Gadeleta, Sergio J.; Kaes, David R.; Manrique, Albert, Volume maintaining osteoinductive/osteoconductive compositions.
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