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Method and apparatus for enhanced drug permeation of skin 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61B-005/05
출원번호 US-0241354 (1988-09-08)
우선권정보 AU-0004342 (1987-09-11); AU-0005676 (1987-11-25)
발명자 / 주소
  • Grinwald Paul M. (434 Balwyn Road North Balwyn AUX 3104)
인용정보 피인용 횟수 : 72  인용 특허 : 9

초록

A method and apparatus for preparation of a selected area of skin to facilitate drug absorption comprises removal of the outermost layers of the skin by gentle abrasion or other means, measuring the change in electrical resistance or impedance of the skin as the outermost layers of the skin are remo

대표청구항

A method of skin preparation to facilitate absorption of drugs comprising the following steps: (a) Removing the outermost layers of the skin by wet or dry abrasion, wherein skin removal is delimited by application to the skin of a single use target masking tape consisting of a disk of adhesive backe

이 특허에 인용된 특허 (9)

  1. Chang Robert W. H. (Roseville MN) Kronzer Joseph P. (Roseville MN), Cleansing pad.
  2. Jacques Steven L. (Somerville MA) McAuliffe Daniel J. (Revere MA) Blank Irvin H. (Belmont MA) Parrish John A. (Weston MA), Controlled removal of human stratum corneum by pulsed laser to enhance percutaneous transport.
  3. Heavner ; Jr. Paul William (Kettering OH) Long Gregor Dean (Libertyville IL), Diagnostic electrode assembly with a skin preparation surface.
  4. York Kenneth K. (2300 N. Edgement St. Los Angeles CA 90027), Disposable applicator.
  5. Sibalis Dan (Stony Brook NY), Indicator for electrophoretic transcutaneous drug delivery device.
  6. Shaw ; IV Alexander F. (Davenport IA), Method for aiding diagnostic scanning of the body of a patient.
  7. Tam Hak W. (Kirkland WA) Modes Vernon E. (Kent WA), Skin preparation device and method used in the application of medical electrodes.
  8. Patrick, Jr., Charles T., Skin preparation method and product.
  9. Peck Carl C. (Rockville MD), Transdermal detection system.

이 특허를 인용한 특허 (72)

  1. Glenn,Gregory M.; Alving,Carl R., Adjuvant for transcutaneous immunization.
  2. Kurnik Ronald T. ; Tamada Janet ; Tierney Michael, Chemical signal-impermeable mask.
  3. Kurnik Ronald T. ; Tamada Janet ; Tierney Michael, Chemical signal-impermeable mask.
  4. Kurnik Ronald T. ; Tamada Janet ; Tierney Michael, Chemical signal-impermeable mask.
  5. Kurnik, Ronald T.; Tamada, Janet; Tierney, Michael, Chemical signal-impermeable mask.
  6. Kurnik, Ronald T.; Tamada, Janet; Tierney, Michael, Chemical signal-impermeable mask.
  7. Mayer David W., Clad composite stent.
  8. Mayer David W., Clad composite stent.
  9. Mayer David W. (Bloomington MN), Clad composite stent.
  10. Mayer David W. (Bloomington MN), Clad composite stent.
  11. Mayer, David W., Clad composite stent.
  12. Kuhl, Michael; Wrba, Peter; Hildebrand, Peter; Reisacher, Martin, Depth measurement and depth control or automatic depth control for a hollow to be produced by a laser processing device.
  13. Kumar, Uday N.; Livingston, Peter H.; Day, Mark J.; Park, Shena H.; Willis, William F.; Righter, William H.; Bahney, Tim, Device features and design elements for long-term adhesion.
  14. Martin,Frank E.; Evans,John D., Device for manipulating a needle or abrader array and method of use.
  15. Crosz ; Jr. Steven J., Electrode patch including position marker for physical health condition tests.
  16. Pettis, Ronald J.; Down, James A.; Harvey, Noel G., Intradermal delivery of substances.
  17. Pettis, Ronald J.; Down, James A.; Harvey, Noel G., Intradermal delivery of substances.
  18. Pettis, Ronald J.; Down, James A.; Harvey, Noel G., Intradermal delivery of substances.
  19. Pettis, Ronald J.; Down, James A.; Harvey, Noel G., Intradermal delivery of substances.
  20. Pettis, Ronald J.; Down, James A.; Harvey, Noel J., Intradermal delivery of substances.
  21. Mikszta,John A.; Alarcon,Jason B.; Dean,Cheryl; Waterston,Andrea, Intradermal delivery of vaccines and gene therapeutic agents via microcannula.
  22. Weaver, James C.; Anderson, R. Rox; Herndon, Terry O; Gowrishankar, T. R.; Gift, Elizabeth A.; Gonzalez, Salvador, Localized molecular and ionic transport to and from tissues.
  23. Kevin R. Heath, Metal medical device.
  24. Henning Timothy P. ; Hiltibran Robert G. ; Cunningham David D. ; Shain Eric B. ; Tarkowski Brian J. ; Young Douglas F., Method and apparatus for obtaining interstitial fluid for diagnostic tests.
  25. Sage, Burton H.; Bock, Carl Randolph, Method and device for abrading skin.
  26. Pettis, Ronald J.; Harvey, Noel; Ginsberg, Barry, Method and device for controlling drug pharmacokinetics.
  27. Pettis, Ronald J.; Harvey, Noel; Ginsberg, Barry, Method and device for controlling drug pharmacokinetics.
  28. Laurent,Phillipe; Mikszta,John A.; Alarcon,Jason B., Method and device for the delivery of a substance including a covering.
  29. Pettis, Ronald J.; Harvey, Noel G.; Down, James A., Method for altering drug pharmacokinetics based on medical delivery platform.
  30. Pettis, Ronald J; Harvey, Noel G; Down, James A, Method for altering drug pharmacokinetics based on medical delivery platform.
  31. Carim Hatim M. ; Burton Scott A., Method for conditioning skin and an electrode by passing electrical energy.
  32. Smith, Alan; Eppstein, Jonathan A.; Messier, Bernadette; Novakovic, Zoran; McRae, Stuart, Method for transdermal delivery of permeant substances.
  33. Smith, Alan; Eppstein, Jonathan A.; Messier, Bernadette; Novakovic, Zoran; McRae, Stuart, Method for transdermal delivery of permeant substances.
  34. Minerath, III,Bernard J.; Buettner,Elizabeth J.; Kruchoski,Benjamin J.; Cohen,Jason C.; Reece,Barry T.; Geiser,Kimberly M., Method of collecting data relating to attributes of personal care articles and compositions.
  35. Minerath, III,Bernard J.; Buettner,Elizabeth J.; Kruchoski,Benjamin J.; Cohen,Jason C.; Reece,Barry T.; Geiser,Kimberly M., Method of measuring attributes of personal care articles and compositions.
  36. Ronald T. Kurnik ; Janet Tamada ; Michael Tierney, Methods of producing an assembly for use in a monitoring device.
  37. Lastovich,Alexander G.; Martin,Frank E.; Haider,M. Ishaq; Clarke,Richard P.; Alarcon,Jason B.; Mikszta,John A.; Dekker, III,John P.; Harding,Weston, Microabrader with controlled abrasion features.
  38. Eppstein Jonathan A. ; Hatch Michael R. ; Yang Difei, Microporation of human skin for drug delivery and monitoring applications.
  39. Eppstein Jonathan A. ; Hatch Michael R. ; Yang Difei, Microporation of human skin for monitoring the concentration of an analyte.
  40. Eppstein, Jonathan A., Microporation of tissue for delivery of bioactive agents.
  41. Eppstein, Jonathan A., Microporation of tissue for delivery of bioactive agents.
  42. Eppstein, Jonathan A., Microporation of tissue for delivery of bioactive agents.
  43. Lastovich, Alexander G.; Alarcon, Jason B.; Dekker, III, John P.; Haider, M. Ishaq; Mikszta, John A.; Martin, Frank E.; O'Connor, Scott A., Microprotrusion arrays and methods for using same to deliver substances into tissue.
  44. Lastovich,Alexander G.; Alarcon,Jason B.; Dekker, III,John P.; Haider,M. Ishaq; Mikszta,John A.; Martin,Frank E.; O'Connor,Scott A., Microprotrusion arrays and methods for using same to deliver substances into tissue.
  45. Weaver, James C.; Anderson, R. Rox; Herndon, Terry O., Microscission processes and procedures.
  46. Mayer David W. (Bloomington MN), Process for manufacturing clad composite stent.
  47. Carim Hatim M. ; Burton Scott A., Reducing artifact in bioelectric signal monitoring.
  48. Sepulveda, Genaro Sebastian; Bahney, Timothy Jon; Park, Shena Hae, Skin abrader.
  49. Sepulveda, Genaro Sebastian; Bahney, Timothy Jon; Park, Shena Hae, Skin abrader.
  50. Chuang, Han; Eslava, Juan P.; Hurley, James P.; Ghosh, Debashis; Krystyniak, Keith; Kellogg, Scott C., Skin permeation device for analyte sensing or transdermal drug delivery.
  51. Chuang, Han; Eslava, Juan P.; Hurley, James P.; Ghosh, Debashis; Krystyniak, Keith; Kellogg, Scott C., Skin permeation device for analyte sensing or transdermal drug delivery.
  52. Haider,M. Ishaq; Lastovich,Alexander G.; Erskine,Timothy J.; Mikszta,John A.; Martin,Frank E.; O'Connor,Scott A.; Alarcon,Jason B.; Dekker, III,John P., Substance delivery via a rotating microabrading surface.
  53. Mikszta, John A.; Brittingham, John M.; Alarcon, Jason; Pettis, Ronald J.; Dekker, III, John P., Topical delivery of vaccines.
  54. Mikszta, John A.; Brittingham, John M.; Alarcon, Jason; Pettis, Ronald J.; Dekker, III, John P., Topical delivery of vaccines.
  55. Glenn, Gregory M.; Alving, Carl R., Transcutaneous immunization without heterologous adjuvant.
  56. Eppstein, Jonathan; McRae, Stuart, Transdermal integrated actuator device, methods of making and using same.
  57. Eppstein, Jonathan; McRae, Stuart, Transdermal integrated actuator device, methods of making and using same.
  58. Eppstein, Jonathan; McRae, Stuart, Transdermal integrated actuator device, methods of making and using same.
  59. McRae, Stuart; Bowerman, Wendy E.; Braun, Stephen Wilson; Spiehl, Regina; Messier, Bernadette; Farquhar, David; Henkel, Erin Koch; O'Leary, Jeremiah Peter; Fisher, Mark James; Kascak, Uros; Lantz, Loren J.; Novakovic, Zoran; Eppstein, Jonathan, Transdermal porator and patch system and method for using same.
  60. Messier, Bernadette; Novakovic, Zoran; O'Leary, Jeremiah Peter; Spiehl, Regina; Bowerman, Wendy E.; Braun, Stephen Wilson; Eppstein, Jonathan; Farquhar, David; Fisher, Mark James; Kascak, Uros; Henkel, Erin Koch; Lantz, Loren J.; McRae, Stuart, Transdermal porator and patch system and method for using same.
  61. Messier, Bernadette; Novakovic, Zoran; O'Leary, Jeremiah Peter; Spiehl, Regina; Bowerman, Wendy E.; Braun, Stephen Wilson; Eppstein, Jonathan; Farquhar, David; Fisher, Mark James; Kascak, Uros; Henkel, Erin Koch; Lantz, Loren J.; McRae, Stuart, Transdermal porator and patch system and method for using same.
  62. Heath Kevin R., Tubular medical endoprostheses.
  63. Heath Kevin R., Tubular medical endoprostheses.
  64. Heath,Kevin R., Tubular medical endoprostheses.
  65. Heath Kevin R., Tubular medical prosthesis.
  66. Abele John E. ; Heath Kevin R., Ultrasonic medical device.
  67. Glenn, Gregory M.; Alving, Carl R., Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response.
  68. Glenn,Gregory M.; Alving,Carl R., Use of penetration enhancers and barrier disruption methods to enhance the immune response of antigen and adjuvant.
  69. Glenn, Gregory M.; Cassels, Frederick J., Vaccine for transcutaneous immunization.
  70. Hughes, Nicholas; Day, Mark; Tamura, Yuriko, Wearable monitor.
  71. Hughes, Nicholas; Day, Mark; Tamura, Yuriko, Wearable monitor.
  72. Hughes, Nicholas; Day, Mark; Tamura, Yuriko, Wearable monitor with arrhythmia burden evaluation.
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