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Method of imaging colorectal carcinoma lesion and composition for use therein 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-049/02
  • C07K-015/28
  • C07K-015/00
출원번호 US-0671132 (1991-03-18)
발명자 / 주소
  • Welt Sydney (New York NY) Divgi Chaitanya R. (New York NY) Yeh Samual (New York NY) Old Lloyd J. (New York NY) Oettgen Herbert F. (New Canaan CT) Real Francisco X. (Barcelona ESX) Sakamoto Junichi (C
출원인 / 주소
  • Sloan-Kettering Institute For Cancer Research (New York NY 02)
인용정보 피인용 횟수 : 39  인용 특허 : 0

초록

This invention provides a method of imaging a colorectal carcinoma lesion in a human patient which comprises administering to the patient a monoclonal antibody capable of binding to a cell surface antigen associated with the coloretal carcinoma lesion and which is labeled with an imaging agent under

대표청구항

The monoclonal antibody AS 33 (HB 8779). The hybridoma cell line which produces the monoclonal antibody of claim 1.

이 특허를 인용한 특허 (39)

  1. Carlos F. Barbas, III ; Christoph Rader ; Gerd Ritter ; Sydney Welt ; Lloyd J. Old, A33 antigen specific immunoglobulin products and uses thereof.
  2. Kataoka, Shiro; Tomura, Takafumi; Otani, Noriko, Anti-A33 antibody.
  3. Kataoka,Shiro; Tomura,Takafumi; Otani,Noriko, Anti-A33 antibody.
  4. Waldman, Scott A.; Park, Jason; Schulz, Stephanie, Compositions and methods for identifying and targeting cancer cells of alimentary canal origin.
  5. Waldman, Scott A.; Park, Jason; Schulz, Stephanie, Compositions and methods for identifying and targeting cancer cells of alimentary canal origin.
  6. Waldman, Scott A.; Park, Jason; Schulz, Stephanie, Compositions and methods for identifying and targeting cancer cells of alimentary canal origin.
  7. Waldman, Scott A.; Park, Jason; Schulz, Stephanie, Compositions and methods for identifying and targeting cancer cells of alimentary canal origin.
  8. Waldman Scott A., Compositions that specifically bind to colorectal cancer cells and methods of using the same.
  9. Waldman Scott A., Compositions that specifically bind to colorectal cancer cells and methods of using the same.
  10. Waldman Scott A. ; Pearlman Joshua M. ; Barber Michael T. ; Schulz Stephanie ; Parkinson Scott J., Compositions that specifically bind to colorectal cancer cells and methods of using the same.
  11. Waldman,Scott A.; Pearlman,Joshua M.; Barber,Michael T.; Schulz,Stephanie; Parkinson,Scott J., Compositions that specifically bind to colorectal cancer cells and methods of using the same.
  12. Waldman,Scott A.; Pearlman,Joshua M.; Barber,Michael T.; Schulz,Stephanie; Parkinson,Scott J., Compositions that specifically bind to colorectal cancer cells and methods of using the same.
  13. King David John,GBX ; Adair John Robert,GBX ; Owens Raymond John,GBX, Humanized antibodies directed against A33 antigen.
  14. Waldman Scott A., Imaging of colorectal cancer using ST receptor binding compounds.
  15. Whitlow Marc D. ; Filpula David R., Linker and linked fusion polypeptides.
  16. Whitlow Marc D. ; Filpula David R., Linker for linked fusion polypeptides.
  17. Kuntsmann Martin P. ; Hollander Irwin ; Hamann Philip, Method for the preparation of substantiallly monomeric calicheamicin derivative/carrier conjugates.
  18. Whitlow Marc D. ; Wood James F. ; Hardman Karl D. ; Bird Robert E. ; Filpula David ; Rollence Michele, Methods for producing multivalent antigen-binding proteins.
  19. Carlos F. Barbas, III ; Christoph Rader ; Gerd Ritter ; Sydney Welt ; Lloyd J. Old, Methods for reducing the effects of cancers that express A33 antigen using A33 antigen specific immunoglobulin products.
  20. Waldman, Scott A, Methods of and kits and compositions for diagnosing colorectal tumors.
  21. Scott A. Waldman, Methods of and kits and compositions for diagnosing colorectal tumors and metastasis thereof.
  22. Waldman Scott A., Methods of and kits and compositions for diagnosing colorectal tumors and metastasis thereof.
  23. Waldman Scott A., Methods of and kits and compositions for diagnosing colorectal tumors and metastasis thereof.
  24. Waldman, Scott A., Methods of and kits and compositions for diagnosing colorectal tumors and metastasis thereof.
  25. Waldman, Scott A.; Carrithers, Stephen L., Methods of and kits and compositions for diagnosing colorectal tumors and metastasis thereof.
  26. Waldman,Scott A., Methods of and kits and compositions for diagnosing colorectal tumors and metastasis thereof.
  27. Waldman Scott A. (Ardmore PA), Methods of diagnosing colorectal tumors and metastasis thereof.
  28. Waldman, Scott A.; Park, Jason; Schulz, Stephanie, Methods of screening and diagnosing esophageal cancer by determining guanylin cyclase C expression.
  29. Welt Sydney ; Ritter Gerd ; Cohen Leonard ; Williams ; Jr. Clarence ; Richards Elizabeth Carswell ; John Mary ; Old Lloyd J., Methods of treating colon cancer utilizing tumor-specific antibodies.
  30. Waldman Scott A., Methods of treating metastatic colorectal cancer with ST receptor binding compounds.
  31. Tsang,Kwong Y.; Arlen,Myron, Monoclonal antibodies against human colon carcinoma-associated antigens and uses therefor.
  32. Whitlow Marc D. ; Wood James F. ; Hardman Karl D. ; Bird Robert E. ; Filpula David ; Rollence Michele, Multivalent antigen-binding proteins.
  33. Whitlow Marc D. ; Wood James F. ; Hardman Karl D. ; Bird Robert E. ; Filpula David ; Rollence Michele, Multivalent antigen-binding proteins.
  34. Whitlow, Marc D.; Wood, James F.; Hardman, Karl D.; Bird, Robert E.; Filpula, David; Rollence, Michele, Multivalent antigen-binding proteins.
  35. Chatterjee Malaya ; Kohler Heinz ; Chatterjee Sunil K. ; Foon Kenneth A., Murine anti-idiotype antibody 3H1.
  36. Chatterjee,Malaya; Kohler,Heinz; Chatterjee,Sunil K.; Foon,Kenneth A., Murine monoclonal anti-idiotype antibody 3H1 sequences for human carcinoembryonic antigen.
  37. Whitlow Marc D. ; Hardman Karl D. ; Bird Robert E. ; Filpula David, Nucleic acid molecules encoding single-chain antigen-binding proteins.
  38. Waldman, Scott A., ST receptor binding compounds and methods of using the same.
  39. Waldman,Scott A., ST receptor binding compounds and methods of using the same.
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