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Repetitive DNA sequence specific for mycobacterium tuberculosis to be used for the diagnosis of tuberculosis 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12Q-001/68
  • C12P-019/34
출원번호 US-0589819 (1990-09-28)
발명자 / 주소
  • Crawford Jack T. (Atlanta GA) Eisenach Kathleen D. (Little Rock AR) Cave M. Donald (Little Rock AR) Bates Joseph H. (Little Rock AR)
출원인 / 주소
  • The Board of Trustees of the University of Arkansas (Little Rock AR 02)
인용정보 피인용 횟수 : 35  인용 특허 : 0

초록

A novel composition and/or methods for the diagnosis of tuberculosis wherein the composition comprises a repetitive DNA segment that is specific for members of the Mycobacterium tuberculosis complex. The DNA segment repeats in the chromosome of Mycobacterium tuberculosis complex, and is conserved in

대표청구항

A complete, isolated and purified, repetitive DNA segment for use in detecting Mycobacterium tuberculosis complex in clinical material, said DNA segment being isolated in clones, l55 and l58, and wherein said clones each contains 400 base-pair Sal1 fragments and 2 flanking Sal1 fragments.

이 특허를 인용한 특허 (35)

  1. Fischer, Gerald W.; Daum, Luke T., Biological specimen collection and transport system.
  2. Fischer, Gerald W.; Daum, Luke T., Biological specimen collection and transport system and method of use.
  3. Fischer, Gerald W.; Daum, Luke T., Biological specimen collection and transport system and method of use.
  4. Fischer, Gerald W; Daum, Luke T., Biological specimen collection and transport system and method of use.
  5. Fischer, Gerald W.; Daum, Luke T., Biological specimen collection/transport compositions and methods.
  6. Fischer, Gerald W.; Daum, Luke T., Composite antigenic sequences and vaccines.
  7. Fischer, Gerald W.; Daum, Luke T., Composite antigenic sequences and vaccines.
  8. Fischer, Gerald W.; Daum, Luke T., Compositions and methods for detecting and identifying nucleic acid sequences in biological samples.
  9. Fischer, Gerald W.; Daum, Luke T., Compositions and methods for detecting, identifying and quantitating mycobacterial-specific nucleic acids.
  10. Fischer, Gerald W.; Daum, Luke T., Compositions and methods for rapid, real-time detection of influenza a virus (H1N1) Swine 2009.
  11. Brown, James F.; Silver, Jonathan E., Device and method for amplifying target nucleic acid.
  12. Brown, James F.; Silver, Jonathan E., Device for amplifying target nucleic acid.
  13. Sandhu Gurpreet S. ; Kline Bruce C. ; Stockman Leslie ; Roberts Glenn D. ; Lewis Marcia E., IS6110 based molecular detection of mycobacterium tuberculosis.
  14. Fischer, Gerald W.; Daum, Luke T., Immunogenic compositions and methods.
  15. Fischer, Gerald W.; Daum, Luke T., Immunogenic compositions and methods.
  16. Fischer, Gerald W.; Daum, Luke T., Immunogenic compositions and methods.
  17. Melkonyan, Hovsep; Cannas, Angela; Tomei, Louis David; Umansky, Samuil R., Kits for diagnosis and monitoring of pathogenic infection by analysis of cell-free pathogenic nucleic acids in urine.
  18. Melkonyan, Hovsep; Cannas, Angela; Tomei, Louis David; Umansky, Samuil R., Kits for diagnosis and monitoring of viral infection by analysis of viral transrenal nucleic acids in urine.
  19. Brown, James F.; Silver, Jonathan E., Method and device for detecting the presence of a single target nucleic acid in a sample.
  20. Brown, James F.; Silver, Jonathan E., Method for detecting the presence of a single target nucleic acid in a sample.
  21. Brown, James F.; Silver, Jonathan E., Method for detecting the presence of a single target nucleic acid in a sample.
  22. Brown, James F.; Silver, Jonathan E., Method for detecting the presence of a single target nucleic acid in a sample.
  23. Brown, James F.; Silver, Jonathan E., Method for detecting the presence of a target nucleic acid sequence in a sample.
  24. Melkonyan, Hovsep; Cannas, Angela; Tomei, Louis David; Umansky, Samuil R., Method for diagnosis and monitoring of viral infection by analysis of viral transrenal nucleic acids in urine.
  25. Brown, James F.; Silver, Jonathan E., Method of loading sample into a microfluidic device.
  26. Brown, James F.; Silver, Jonathan E., Methods of detecting amplified product.
  27. Umansky, Samuil R.; Melkonyan, Hovsep S.; Scheinker, Vladimir S., Methods of detecting cell-free miRNA in urine and blood.
  28. Haaland David M. (Albuquerque NM) Jones Howland D. T. (Albuquerque NM) Thomas Edward V. (Albuquerque NM), Multivariate classification of infrared spectra of cell and tissue samples.
  29. Guesdon Jean-Luc,FRX ; Thierry Dominique,FRX ; Ullmann Agnes,FRX ; Gicquel Brigitte,FRX ; Brisson-Noel Anne,FRX, Mycobacterial nucleic acid hybridization probes and methods of use.
  30. Nano Francis E.,CAX, Mycobacterium tuberculosis DNA sequences encoding immunostimulatory peptides.
  31. Hammond Philip W., Nucleic acid probes to mycobacterium tuberculosis.
  32. Plikaytis Bonnie B. (Tucker GA) Shinnick Thomas M. (Atlanta GA) Crawford Jack T. (Dunwoody GA), Rapid amplification-based subtyping of mycobacterium tuberculosis.
  33. Fischer, Gerald W.; Daum, Luke T., Rapid methods for the extraction of nucleic acids from biological samples.
  34. Fischer, Gerald W.; Daum, Luke T., Rapid methods for the extraction of nucleic acids from biological samples.
  35. Down James A. (Cary NC) Walters Adriann H. (Durham NC) Dey Margaret S. (Apex NC) Howard Deborah R. (Durham NC) Little Michael C. (Raleigh NC) Keating William E. (Durham NC), Sample processing method for Mycobacterium tuberculosis.
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