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Virus-resistant transgenic mice 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12N-015/00
출원번호 US-0092514 (1987-09-03)
발명자 / 주소
  • Wagner Thomas E. (Athens OH) Chen Xiao-Zhuo (Athens OH)
출원인 / 주소
  • Ohio University/Edison Animal Biotechnolgy Center (Athens OH 02)
인용정보 피인용 횟수 : 69  인용 특허 : 0

초록 ▼

A transgenic mouse with enhanced viral resistance transmissible to its offspring is prepared by introduction of a gene encoding a human interferon having antiviral activity into a host mouse. The gene encodes the interferon of a different animal species and therefore its expression product is less t

대표청구항 ▼

A transgenic mouse whose somatic and germ cells contain and express a gene coding for human beta interferon at a level sufficient to provide antiviral activity in said mouse, said gene having been introduced into said mouse or an ancestor of said mouse at an embryonic stage, and wherein said gene is

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