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Sol-gel encapsulated enzyme 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12N-011/04
  • C12N-011/14
  • C12N-011/08
  • C03C-003/00
출원번호 US-0744524 (1991-08-13)
발명자 / 주소
  • Dunn Bruce S. (Los Angeles) Valentine Joan S. (Encino) Zink Jeffrey I. (Sherman Oaks) Ellerby Lisa (Los Angeles) Nishida Fumito (Los Angeles) Nishida Clinton (Los Angeles) Yamanaka Stacey A. (Los Ang
출원인 / 주소
  • The Regents of the University of California (Oakland CA 02)
인용정보 피인용 횟수 : 57  인용 특허 : 0

초록

An active biological material encapsulated in a glass is formed using a sol-gel process. A metal alkoxide is mixed with water and exposed to ultrasonic energy at a pH≤2 to form a single phase solution which is then buffered to a pH between about 5 and 7. The buffered solution is then mixed with the

대표청구항

A process for the production of a porous, transparent sol-gel glass containing an alcohol sensitive active biological material entrapped therein comprising: (a) forming a single phase sol by mixing a metal alkoxide in a non-alcoholic medium comprising water and an acid catalyst in a container expose

이 특허를 인용한 특허 (57)

  1. Lapidot, Noa; Blanca, Merav; Rottman, Claudio; Naigertsik, Oleg, Agent-encapsulating micro-and nanoparticles, methods for preparation of same and products containing same.
  2. Amiss, Terry J.; Nycz, Colleen M.; Pitner, J. Bruce; Sherman, Douglas B.; Wright, David J., Binding protein as biosensors.
  3. Dordick, Jonathan S.; Clark, Douglas S., Biocatalytic solgel microarrays.
  4. Dordick,Jonathan S.; Clark,Douglas S., Biocatalytic solgel microarrays.
  5. Lapidot, Noa; Magdassi, Shlomo; Avnir, David; Rottman, Claudi; Gans, Orit; Seri-Levy, Alon, Composition exhibiting enhanced formulation stability and delivery of topical active ingredients.
  6. Lapidot, Noa; Magdassi, Shlomo; Avnir, David; Rottman, Claudio; Gans, Orit; Seri-Levy, Alon, Composition exhibiting enhanced formulation stability and delivery of topical active ingredients.
  7. Lapidot, Noa; Magdassi, Shlomo; Avnir, David; Rottman, Claudio; Gans, Orit; Seri-Levy, Alon, Composition exhibiting enhanced formulation stability and delivery of topical active ingredients.
  8. Sertchook, Hanan; Toledano, Ofer; Bar-Simantov, Haim, Compositions for the treatment of rosacea.
  9. Toledano, Ofer; Sertchook, Hanan; Loboda, Natalia; Bar-Simantov, Haim; Shapiro, Leora; Abu-Reziq, Raed, Compositions for topical application comprising a peroxide and retinoid.
  10. Bakul Dave, Dehydrogenase enzymatic synthesis of methanol.
  11. Fitzgerald Stephen Peter,GBX ; Lamont John Victor,GBX ; McConnell Robert Ivan,GBX, Dried tetramethoxysilane sol-gel containing a leachable reagent.
  12. Pope Edward J. A., Encapsulation of animal and microbial cells in an inorganic gel prepared from an organosilicon.
  13. Pope Edward J. A. (447 Lorenzo Dr. Agoura CA 91301), Encapsulation of living tissue cells in an organosilicon.
  14. Pope Edward J. A., Encapsulation of living tissue cells in inorganic microspheres prepared from an organosilicon.
  15. Alarcon, Javier; Knors, Christopher J.; Pitner, J. Bruce, Entrapped binding protein as biosensors.
  16. Fothergill, Michael David; Gibson, Timothy; Sobany, Gerard Garcia, Gas phase biocatalysis method and process.
  17. Dave, Bakul C.; Rao, Mukti S., Glass composite materials containing alkoxosilane derivative having alterable charge, hydrophobic and hydrophilic groups.
  18. Acevedo, Edwin Moncada; Pires, Gilvan Pozzobon; Dos Santos, João Henrique Zimnoch, Hybrid chemical sensor, and, sensitive polymeric composition.
  19. Reetz Manfred T.,DEX ; Simpelkamp Jorg,DEX ; Zonta Albin,DEX, Immobilization of lipases by entrapment in silica matrices.
  20. Sasaki Darryl Y. ; Loy Douglas A. ; Yamanaka Stacey A., Immobilized lipid-bilayer materials.
  21. Dordick,Jonathan S.; Srinivasan,Aravind; Kim,Jungbae; Sherman,David H.; Clark,Douglas S., In vitro metabolic engineering on microscale devices.
  22. Ducheyne Paul ; Radin Shulamith ; Santos Erick Manuel, Incorporation of biological molecules into bioactive glasses.
  23. Ducheyne Paul ; Radin Shulamith ; Santos Erick Manuel, Incorporation of biological molecules into bioactive glasses.
  24. Ducheyne Paul ; Radin Shulamith ; Santos Erick Manuel, Incorporation of biological molecules into bioactive glasses.
  25. Ducheyne Paul (Rosemont PA) Radin Shulamith (Voorhees NJ) Santos Erick M. (Philadelphia PA), Incorporation of biologically active molecules into bioactive glasses.
  26. Ducheyne Paul ; Radin Shulamith ; Santos Erick Manuel, Incorporation of biologically active molecules into bioactive glasses.
  27. Ducheyne Paul ; Radin Shulamith ; Santos Erick Manuel, Incorporation of biologically active molecules into bioactive glasses.
  28. Liotta Lance A. ; Christiansen Bryan C. ; Day Alan R. ; Harlacher Tabitha ; Paweletz Katherine, Light-emitting immunoassay.
  29. Novak, Paige J.; Arnold, William A.; Surdo, Erin M., Membranes for wastewater-generated energy and gas.
  30. Toledano, Ofer; Sertchook, Hanan; Loboda, Natalia; Bar-Simantov, Haim, Metal oxide coating of water insoluble ingredients.
  31. Kessler, Vadim G.; Seisenbaeva, Gulaim A.; Håkansson, Sebastian; Unell, Maria, Metal oxide hydrogels and hydrosols, their preparation and use.
  32. Rauh R. David, Metal oxide matrix biosensors.
  33. Chu Wen-Hua ; Ferrari Mauro, Method for forming a filter.
  34. Jokinen, Mika; Viitala, Reeta; Jalonen, Harry, Method for preparing adjustably bioresorbable sol-gel derived SiO2 .
  35. Naigertsik, Oleg; Rothschild, Sorel; Rottman, Claudio, Microcapsules loaded with active ingredients and a method for their preparation.
  36. Keller Christopher G. ; Ferrari Mauro, Microfabricated capsules for immunological isolation of cell transplants.
  37. Chu Wen-Hwa ; Ferrari Mauro, Microfabricated filter with specially constructed channel walls, and containment well and capsule constructed with such filters.
  38. Chu Wen-Hwa ; Ferrari Mauro, Micromachined capsules having porous membranes and bulk supports.
  39. Chu Wen-Hua ; Ferrari Mauro, Micromachined porous membranes with bulk support.
  40. Frank V. Bright ; Brett R. Wenner ; Meagan A. Doody ; Gary A. Baker, Microsensor arrays and method of using same for detecting analytes.
  41. Steinthal,Gregory; Sunshine,Steven; Burch,Tim; Plotkin,Neil; Hsiung,Chang Meng, Non-specific sensor array detectors.
  42. Medina Perilla, Jorge Alberto; Garcia Mora, Angela Maria; Arias Herrera, Andrea Marcela; Joven Pineda, Ronald Vicente, Oxygen-absorbing compound encapsulated in a silica matrix and method for the production thereof.
  43. Rock Ronald S. ; Stowell Michael H. B., Photoresponsive sunscreen compositions.
  44. Rock Ronald S. ; Stowell Michael H. B., Photoresponsive sunscreen compositions.
  45. Friedrich, Thomas, Polycondensation of organic silicon compounds.
  46. Rambo, Brett M.; Bucholz, Tracy L.; Powell, Dawn C.; Weber, Luke E.; Linder, Alexander J.; Duesing, Caroline M. H.; Zaks, Aleksey, Polysilicate-polysilicone enzyme immobilization materials.
  47. Davé, Bakul C.; Rao, Mukti S., Porous glass composite material.
  48. Lin, Chhiu-Tsu, Sensor for detecting compounds.
  49. Wackett, Lawrence P.; Aksan, Alptekin; Sadowsky, Michael J; Reategui, Eduardo; Kasinkas, Lisa, Silica encapsulated biomaterials.
  50. Reategui, Eduardo; Kasinkas, Lisa; Aksan, Alptekin, Silica-matrix forming compositions, materials formed therefrom, and methods of using the same.
  51. Charych Deborah H. ; Sasaki Darryl ; Yamanaka Stacey, Sol-gel matrices for direct colorimetric detection of analytes.
  52. Deborah H. Charych ; Darryl Sasaki ; Stacey Yamanaka, Sol-gel matrices for direct colorimetric detection of analytes.
  53. C. Jeffrey Brinker ; Carol S. Ashley ; Rimple Bhatia ; Anup K. Singh, Sol-gel method for encapsulating molecules.
  54. Lapidot Noa,ILX ; Magdassi Shlomo,ILX ; Avnir David,ILX ; Rottman Claudio,ILX ; Gans Orit,ILX ; Seri-Levy Alon,ILX, Sunscreen composition containing sol-gel microcapsules.
  55. Noa Lapidot IL; Shlomo Magdassi IL; David Avnir IL; Claudio Rottman IL; Orit Gans IL; Alon Seri-Levy IL, Sunscreen composition containing sol-gel microcapsules.
  56. Novak, Paige J.; Arnold, William Alan; Aksan, Alptekin, System and membrane for wastewater-generated energy and gas.
  57. Wicks George G. (Aiken SC) Livingston Ronald R. (Aiken SC) Baylor Lewis C. (North Augusta SC) Whitaker Michael J. (North Augusta SC) O\Rourke Patrick E. (Martinez GA), Tetraethyl orthosilicate-based glass composition and method.
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