[특허]Immunoagglutination measurement apparatus

Immunoagglutination measurement apparatus 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	G01N-031/02 G01N-035/02
출원번호	US-0709062 (1991-05-30)
우선권정보	JP-0086916 (1988-04-08)
발명자 / 주소	Okada Satoru (Hyogo JPX) Mizuno Yoshiteru (Hyogo JPX) Izumi Takayoshi (Hyogo JPX) Otani Toshihiro (Hyogo JPX)
출원인 / 주소	Toa Medical Electronics Co., Ltd. (Kobe JPX 03)
인용정보	피인용 횟수 : 79 인용 특허 : 0

초록 ▼

A buffer solution is sampled from a buffer solution vessel and is dispensed into a reaction vessel on a reaction table by first sampling/dispensing means, and a specimen containing an antigen or antibody to be measured is sampled from a specimen vessel and is dispensed into the reaction vessel by second sampling/dispensing means. A reagent containing insoluble carriers to which is bonded an antibody or antigen that specifically reacts with the antigen or antibody in the specimen is sampled from a reagent vessel and dispensed into the reaction vessel by third sampling/dispensing means. The entire reaction table is shaken continuously during mixing of the buffer solution, reagent and specimen, and the reaction vessel is maintained in an isothermal state. A stable antigen-antibody reaction in the resulting reaction solution is thus promoted to form an agglutinate of the insoluble carriers. The reaction solution is sampled from the reaction vessel and dispensed into a sample chamber by fourth sampling/dispensing means. The dispensed reaction solution is transferred to a detector through which the insoluble carriers are passed and in which a signal is generated based upon a difference in terms of electrical or optical characteristics. The degree of agglutination of the insoluble carriers is obtained as a numerical value, thus making it possible to quantify the antigen or antibody of interest contained in the specimen.

대표청구항 ▼

An immunoagglutination measurement apparatus for mixing together a specimen from a specimen vessel and a reagent, said apparatus comprising: a base; a reversibly rotatable buffer solution table mounted on said base and on which a plurality of buffer solution vessels are mounted; a first temperature regulating means in thermal communication with the buffer solution vessels for maintaining the buffer solution vessels in an isothermal state; a reversibly rotatable reagent table mounted on said base and on which a plurality of reagent vessels are mounted; a second temperature regulating means in thermal communication with the reagent vessels for maintaining the reagent vessels in an isothermal state; a reversibly rotatable and shakable reaction table mounted on said base and on which a plurality of reaction vessels are supported; a third temperature regulating means in thermal communication with the reaction vessels for maintaining the reaction vessels in an isothermal state; first sampling and dispensing means mounted to said base for sampling a buffer solution from the buffer solution vessels and dispensing the buffer solution into the reaction vessels; second sampling and dispensing means mounted to said base for sampling a specimen from the specimen vessels and dispensing the specimen into the reaction vessels; third sampling and dispensing means mounted to said base for sampling a reagent from the reagent vessels and dispensing the reagent into the reaction vessels; fourth sampling an dispensing means mounted to said base for sampling a reaction solution, in which an agglutination reaction is brought about by mixing of the buffer solution, specimen and reagent, from the reaction vessels and dispensing the reaction solution into a sample chamber communicating with a detection section; a retainer; a reaction table shaft integrally attached to said reaction table, said reaction table shaft having a proximal end freely rotatably attached to said retainer and a distal end integrally attached to said reaction table to freely rotatably support said reaction table for rotation about a central axis defined by said reaction table shaft; one or more retainer shafts freely rotatably attached to said base at a proximal end of the retainer shafts, and eccentrically coupled to said retainer at a distal end thereof whereby rotation of the retainer shafts effects shaking of the retainer relative to the base, thereby shaking the reaction table; a static balancer attached to said one or more retainer shafts for rotation therewith to reduce vibrations produced by movement of the center of gravity of the retainer and reaction table; and measurement means for measuring the amount of agglutinization of the reaction solution.

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IPC	Description
A	생활필수품
A62	인명구조; 소방(사다리 E06C)
A62B	인명구조용의 기구, 장치 또는 방법(특히 의료용에 사용되는 밸브 A61M 39/00; 특히 물에서 쓰이는 인명구조 장치 또는 방법 B63C 9/00; 잠수장비 B63C 11/00; 특히 항공기에 쓰는 것, 예. 낙하산, 투출좌석 B64D; 특히 광산에서 쓰이는 구조장치 E21F 11/00)
A62B-1/08	.. 윈치 또는 풀리에 제동기구가 있는 것

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Immunoagglutination measurement apparatus 원문보기

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Immunoagglutination measurement apparatus 원문보기

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이 특허를 인용한 특허 (79)

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