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Poly(alkylene oxide) amino acid copolymers and drug carriers and charged copolymers based thereon 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-031/74
  • A61K-039/00
  • C08G-069/08
출원번호 US-0726301 (1991-07-05)
발명자 / 주소
  • Zalipsky Samuel (Princeton NJ) Bolikal Durgadas (Edison NJ) Nathan Aruna (Piscataway NJ) Kohn Joachim B. (Highland Park NJ)
출원인 / 주소
  • Enzon, Inc. (South Plainfield NJ 02)
인용정보 피인용 횟수 : 241  인용 특허 : 0

초록

Copolymers of poly(alkylene oxides) and amino acids or peptide sequences are disclosed, which amino acids or peptide sequences have pendant functional groups that are capable of being conjugated with pharmaceutically active compounds for drug delivery systems and cross-linked to form polymer matrice

대표청구항

A polymer comprised of one or more recurring structural units independently represented by the formula: [Figure] wherein R1 is a poly(alkylene oxide) copolymerized with R2, which is an amino acid or peptide sequence containing two amino groups and at least one pendant carboxylic acid group.

이 특허를 인용한 특허 (241)

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