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[미국특허] Vectored drug delivery system using a cephaloplastin linking agent and a methed of using the system 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-037/00
  • A61K-049/00
  • C07K-003/08
  • C07K-017/00
출원번호 US-0786044 (1991-10-31)
발명자 / 주소
  • Sharma Yash P. (8210 Labbe La. Vienna VA 22180)
인용정보 피인용 횟수 : 78  인용 특허 : 0

초록

The subject invention relates to a novel method for vectored delivery of physiologically-active chemical agents to a target organ, tissue or cell of interest and uses thereof. In particular, medical vectoring reagents which localize in a specific target organ, tissue or cell are conjugated with a dr

대표청구항

A composition for the vectored selective delivery of a therapeutically-active agent to a desired mammalian target system, organ, tissue or cell comprising a conjugate composed of a pharmaceutically-acceptable non-toxic organ-specific, non-antibody vectoring reagent selective for said organ tissue or

이 특허를 인용한 특허 (78) 인용/피인용 타임라인 분석

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  11. Curiel David T. ; Birnstiel Max L.,ATX ; Cotten Matthew,ATX ; Wagner Ernst,ATX ; Zatloukal Kurt,ATX ; Plank Christian,ATX ; Oberhauser Berndt,ATX ; Schmidt Walter G. M.,ATX, Composition for introducing nucleic acid complexes into higher eucaryotic cells.
  12. Reyes, Joe, Composition to boost libido.
  13. Zhang, Sheng; Azevedo, Max; Ruiz, Sr., Rafael, Curing accelerator and method of making.
  14. Zhang, Sheng; Ruiz, Sr., Rafael; Azevedo, Max, Curing accelerator and method of making.
  15. Lee, Jeoung Soo; Webb, Charles Kenneth; Zimmerman, Robert; Ruiz, Sr., Rafael, Cyanoacrylate tissue adhesives.
  16. Lee, Jeoung Soo; Webb, Charles Kenneth; Zimmerman, Robert; Ruiz, Sr., Rafael; Zhang, Sheng, Cyanoacrylate tissue adhesives.
  17. Zhang, Sheng; Ruiz, Sr., Rafael; Azevedo, Max, Cyanoacrylate tissue adhesives with desirable permeability and tensile strength.
  18. Zhang, Sheng; Ruiz, Rafael, Cyanoacrylate-based liquid microbial sealant drape.
  19. Charles, Matthew, Formulations of human tissue kallikrein-1 for parenteral delivery and related methods.
  20. Tsibris John C. M. ; Porter Kathy B., Guinea pig model for leiomyomas.
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  26. Hadden, John W., Immunotherapy for reversing immune suppression.
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  28. Zhang, Sheng; Ruiz, Sr., Rafael, Low dose gamma sterilization of liquid adhesives.
  29. Scott, Timothy C.; Dees, H. Craig; Wachter, Eric A., Medicaments for chemotherapeutic treatment of disease.
  30. Silvia S. Jurisson ; Thomas P. Quinn ; Michael F. Giblin, Melanotropin analogs for potential radiopharmaceuticals for diagnosis and treatment of melanoma.
  31. Vardimon Lily,ILX, Method and composition for treating neuronal degeneration.
  32. Harpal S. Mangat ; Gerry Ballough ; Gary Brown, Method and composition for treatment of ischemic neuronal reperfusion injury.
  33. Goldenberg Milton David, Method and kit for imaging and treating organs and tissues.
  34. Norman ; Jr. James G., Method for decreasing severity of acute and chronic pancreatitis.
  35. Zuckerman,Kenneth S.; Liu,Richard Y., Method for the inhibition of function of STAT transcription factors.
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  45. Zhang, Sheng; Ruiz, Rafael, Method of preparing adhesive compositions for medical use: single additive as both the thickening agent and the accelerator.
  46. Levy, Efrat, Methods and compositions relating to cystatin C.
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  55. Jarvis, Gary A.; John, Constance M.; Leffler, Hakon, N-terminally truncated galectin-3 for use in treating cancer.
  56. Chopp, Michael; Zhang, Rui Lan, Nitric oxide donors for inducing neurogenesis.
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  62. De Colle, Cyril; Pasricha, Pankaj; Wustrow, David, Prodrugs of metopimazine.
  63. Spallholz Julian E. ; Reid Ted W., Selenium carrier conjugates.
  64. Reed Eddie (Germantown MD) Lee Kang Bo (Gaithersburg MD), Sensitive assay method for measuring gallium levels in body tissues and fluids.
  65. Zhang, Sheng; Ruiz, Rafael, Stable and sterile tissue adhesive composition with a controlled high viscosity.
  66. Zhang, Sheng; Ruiz, Sr., Rafael; Phelps, Shannon, Sterilized compositions of cyanoacrylate monomers and naphthoquinone 2,3-oxides.
  67. Zhang, Sheng; Ruiz, Sr., Rafael, Sterilized liquid compositions of cyanoacrylate monomer mixtures.
  68. Zhang, Sheng; Ruiz, Sr., Rafael, Sterilized liquid compositions of cyanoacrylate monomer mixtures.
  69. Segev, David, System for delivering therapeutic agents into living cells and cells nuclei.
  70. Dees, H. Craig; Scott, Timothy C.; Smolik, John; Wachter, Eric A.; Fisher, Walter G., Topical medicaments and methods for photodynamic treatment of disease.
  71. Glenn, Gregory M.; Alving, Carl R., Transcutaneous immunization without heterologous adjuvant.
  72. Glenn, Gregory M.; Alving, Carl R., Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response.
  73. Glenn,Gregory M.; Alving,Carl R., Use of penetration enhancers and barrier disruption methods to enhance the immune response of antigen and adjuvant.
  74. Glenn, Gregory M.; Cassels, Frederick J., Vaccine for transcutaneous immunization.
  75. Hadden, John W.; Signorelli, Kathy; Egan, James, Vaccine immunotherapy.
  76. Hadden, John W., Vaccine immunotherapy for immune suppressed patients.
  77. Hadden,John W., Vaccine immunotherapy for immune suppressed patients.
  78. Perera, Ranjan, miR-211 expression and related pathways in human melanoma.

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