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Concentrate of thrombin coagulable proteins, the method of obtaining same and therapeutical use thereof 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-035/16
  • A61K-009/14
출원번호 US-0873106 (1992-04-24)
우선권정보 FR-0010798 (1987-07-30)
발명자 / 주소
  • Burnouf-Radosevich Miryana (Wavrin FRX) Burnouf Thierry (Wavrin FRX)
출원인 / 주소
  • Centre Regional de Transfusion Sanguine de Lille (Lille FRX 03)
인용정보 피인용 횟수 : 94  인용 특허 : 0

초록 ▼

The invention provides a thrombin coagulable protein concentrate,, the preparation thereof and the therapeutic use thereof. This concentrate has a fibrinogen content greater than 70% and a sufficient amount of endogenous Factor XIII. It may be solubilized at ambient temperature. Its preparation comp

대표청구항 ▼

A method for preparing a lyophilized plasma-derived protein concentrate comprising Factor XIII, fibronectin and more than 70% fibrinogen, said concentrate being clottable in the presence of thrombin and calcium to form biological glue, which comprises the steps of: precipitating a non-cryoprecipitat

이 특허를 인용한 특허 (94)

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  27. Semler, Eric J.; Shikhanovich, Roman; Callahan, Alex B.; Truncale, Katherine Gomes; Yannariello-Brown, Judith I.; Huang, Yen-Chen, Cancellous construct with support ring for repair of osteochondral defects.
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