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[미국특허] Three-dimensional skin culture system 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12N-005/00
  • C12M-003/00
출원번호 US-0575518 (1990-08-30)
발명자 / 주소
  • Naughton Gail K. (Groton VT) Naughton Brian A. (Groton VT)
출원인 / 주소
  • Advanced Tissue Sciences, Inc. (La Jolla CA 02)
인용정보 피인용 횟수 : 114  인용 특허 : 0

초록

The present invention relates to a three-dimensional cell culture system which can be used to culture a variety of different cells and tissues in vitro for prolonged periods of time. In accordance with the invention, cells derived from a desired tissue are inoculated and grown on a pre-established s

대표청구항

A three-dimensional skin culture comprising melanocytes and keratinocytes cultured on a living stromal tissue prepared in vitro, comprising stromal cells and connective tissue proteins naturally secreted by the stromal cells attached to and substantially enveloping a framework composed of a biocompa

이 특허를 인용한 특허 (114) 인용/피인용 타임라인 분석

  1. Wilson,John R., Apparatus and method for culturing and preserving tissue constructs.
  2. Peterson Alvin ; Landeen Lee K. ; Bennett John ; Gee Jason ; Chesla Scott ; Zeltinger Joan ; Flatt James H. ; Applegate Mark A. ; Dunkelman Noushin ; Kemmerrer Stephen V., Apparatus and method for simulating in vivo conditions while seeding and culturing three-dimensional tissue constructs.
  3. Flatt James H. ; Applegate Mark A. ; Peterson Alvin, Apparatus and method for sterilizing, seeding, culturing, storing, shipping and testing replacement cartilage tissue constructs.
  4. Dunkelman Noushin ; Peterson Alvin E. ; Landeen Lee Kevin ; Zeltinger Joan, Apparatus and method for sterilizing, seeding, culturing, storing, shipping and testing tissue, synthetic or native, va.
  5. Kurjan Christine ; Applegate Mark A. ; Flatt James H. ; Applegate Dawn Orton ; Bloom Nicole ; Baumgartner Mark, Apparatus for the large scale growth and packaging of cell suspensions and three-dimensional tissue cultures.
  6. Weiss Lee E. ; Calvert Jay Wynn, Assembled scaffolds for three dimensional cell culturing and tissue generation.
  7. Lang, Philipp; Steines, Daniel, Assessing the condition of a joint and assessing cartilage loss.
  8. Altman Gregory ; Kaplan David ; Vunjak-Novakovic Gordana ; Martin Ivan,CHX, Bioengineered anterior cruciate ligament.
  9. Murphy, Michael P.; Ronfard, Vincent, Bioengineered tissue constructs and methods for producing and using thereof.
  10. Abraham,Ginger A.; Carr, Jr.,Robert M., Bioengineered tubular graft prostheses.
  11. Abraham,Ginger A.; Carr, Jr.,Robert M.; Huynh,Tam; Hagen,Per Otto; Davies,Mark, Bioengineered vascular graft support prostheses.
  12. Hopkins, Richard A.; Hoffman-Kim, Diane, Cardiac valve replacement.
  13. Naughton Gail K., Compositions and methods for production and use of an injectable naturally secreted extracellular matrix.
  14. Naughton, Gail K.; Horwitz, David L.; Applegate, Mark A.; Zeltinger, Joan; Mansbridge, Jonathan N.; Kern, Andreas; Landeen, Lee K.; Ratcliffe, Anthony; Pinney, R. Emmett, Conditioned cell culture medium compositions and methods of use.
  15. Naughton, Gail K.; Horwitz, David L.; Applegate, Mark A.; Zeltinger, Joan; Mansbridge, Jonathan N.; Kern, Andreas; Landeen, Lee K.; Ratcliffe, Anthony; Pinney, R. Emmett, Conditioned cell culture medium compositions and methods of use.
  16. Naughton, Gail K.; Horwitz, David L.; Applegate, Mark A.; Zeltinger, Joan; Mansbridge, Jonathan N.; Kern, Andreas; Landeen, Lee K.; Ratcliffe, Anthony; Pinney, R. Emmett, Conditioned cell culture medium compositions and methods of use.
  17. Naughton, Gail K.; Horwitz, David L.; Applegate, Mark; Zeltinger, Joan; Mansbridge, Jonathan; Kern, Andreas; Landeen, Lee K.; Ratcliffe, Anthony; Pinney, R. Emmett, Conditioned cell culture medium compositions and methods of use.
  18. Badylak, Stephen F., Conditioned decellularized native tissues for tissue restoration.
  19. Naughton, Gail K.; Ziegler, Frank; Baumgartner, Mark; Nickey, Kyle, Conditioned medium and extracellular matrix compositions from cells cultured under hypoxic conditions for methods of treating tissue injury.
  20. Mitchell, Shannon; Koh, Jennifer; Prabhakar, Vikas; Niklason, Laura, Decellularized tissue engineered constructs and tissues.
  21. Vandenburgh, Herman H., Delivery of bioactive compounds to an organism.
  22. Bellomo, Stephen F.; Lippin, Itzhak; Piva, Guillermo Alberto; Rosenberg, Lior; Bukhman, Mordechay; Stern, Baruch S.; Shalhevet, David; Shavitt, Menachem D.; Pearlman, Andrew L.; Shani, Noam; Almon, Einat, Dermal micro-organs, methods and apparatuses for producing and using the same.
  23. Bellomo, Stephen F.; Lippin, Itzhak; Piva, Guillermo Alberto; Rosenberg, Lior; Bukhman, Mordechay; Stern, Baruch S.; Shalhevet, David; Shavitt, Menachem D.; Pearlman, Andrew L.; Shani, Noam; Almon, Einat, Dermal micro-organs, methods and apparatuses for producing and using the same.
  24. Bellomo, Stephen F.; Lippin, Itzhak; Piva, Guillermo Alberto; Rosenberg, Lior; Bukhman, Mordechay; Stern, Baruch S.; Shalhevet, David; Shavitt, Menachem D.; Pearlman, Andrew L.; Shani, Noam; Almon, Einat, Dermal micro-organs, methods and apparatuses for producing and using the same.
  25. Bellomo, Stephen F.; Lippin, Itzhak; Piva, Guillermo Alberto; Rosenberg, Lior; Bukhman, Mordechay; Stern, Baruch S.; Shalhevet, David; Shavitt, Menachem D.; Pearlman, Andrew L.; Shani, Noam; Almon, Einat, Dermal micro-organs, methods and apparatuses for producing and using the same.
  26. Bellomo, Stephen F.; Lippin, Itzhak; Piva, Guillermo Alberto; Rosenberg, Lior; Bukhman, Mordechay; Stern, Baruch S.; Shalhevet, David; Shavitt, Menachem D.; Pearlman, Andrew L.; Shani, Noam; Almon, Einat, Dermal micro-organs, methods and apparatuses for producing and using the same.
  27. Bellomo, Stephen F.; Lippin, Itzhak; Piva, Guillermo Alberto; Rosenberg, Lior; Bukhman, Mordechay; Stern, Baruch S.; Shalhevet, David; Shavitt, Menachem D.; Pearlman, Andrew L.; Shani, Noam; Almon, Einat, Dermal micro-organs, methods and apparatuses for producing and using the same.
  28. Bellomo, Stephen F.; Lippin, Itzhak; Piva, Guillermo Alberto; Rosenberg, Lior; Bukhman, Mordechay; Stern, Baruch S.; Shalhevet, David; Shavitt, Menachem D.; Pearlman, Andrew L.; Shani, Noam; Almon, Einat, Dermal micro-organs, methods and apparatuses for producing and using the same.
  29. Bellomo, Stephen F.; Okun, Alex; Fuerst, Yaron; Shalhevet, David; Amir, Elisha; Bukhman, Mordechay, Dermal micro-organs, methods and apparatuses for producing and using the same.
  30. Bellomo, Stephen F.; Okun, Alex; Fuerst, Yaron; Shalhevet, David; Amir, Elisha; Bukhman, Mordechay, Dermal micro-organs, methods and apparatuses for producing and using the same.
  31. Bellomo, Stephen F.; Okun, Alex; Fuerst, Yaron; Shalhevet, David; Amir, Elisha; Bukhman, Mordechay, Dermal micro-organs, methods and apparatuses for producing and using the same.
  32. Barolet, Daniel; Auclair, Mathieu; Boucher, Annie, Device for the treatment of mammalian tissues.
  33. Naughton Brian A. ; Halberstadt Craig R. ; Sibanda Benson, Diffusion gradient bioreactor and extracorporeal liver device.
  34. Grosse, Thomas, Engineered tissue scaffolds and supports therefor.
  35. Mooney David J. ; Rutherford Robert B., Engineering oral tissues.
  36. Badylak, Stephen F.; Lindberg, Khristina; Boder, George B.; Voytik-Harbin, Sherry, Enhanced submucosal tissue graft constructs.
  37. Badylak,Stephen F; Lindberg,Christina; Boder,George B.; Voytik Harbin,Sherry, Enhanced submucosal tissue graft constructs.
  38. Stephen F. Badylak ; Christina Lindberg ; George B. Boder ; Sherry Voytik-Harbin, Enhanced submucosal tissue graft constructs.
  39. Atala, Anthony; Soker, Shay, Enhancement of angiogenesis to grafts using cells engineered to produce growth factors.
  40. Naughton, Gail K.; Ziegler, Frank; Baumgartner, Mark; Nickey, Kyle, Extracellular matrix compositions produced under hypoxic culture conditions.
  41. Vacanti, Joseph P.; Shin, Young-Moon Michael; Ogilvie, Jennifer; Sevy, Alexander; Maemura, Tomoyuki; Ishii, Osamu; Kaazempur-Mofrad, Mohammad Reza; Borenstein, Jeffrey T.; King, Kevin R.; Wang, Chiao-Chun; Weinberg, Eli, Fabrication of tissue lamina using microfabricated two-dimensional molds.
  42. Vacanti, Joseph P.; Shin, Young-Moon M.; Ogilvie, Jennifer; Sevy, Alexander; Maemura, Tomoyuki; Ishii, Osamu; Kaazempur-Mofrad, Mohammad R.; Borenstein, Jeffrey T.; King, Kevin R.; Wang, Chiao-Chun; Weinberg, Eli, Fabrication of vascularized tissue using microfabricated two-dimensional molds.
  43. Vacanti, Joseph P.; Shin, Young-Moon Michael; Ogilvie, Jennifer; Sevy, Alexander; Maemura, Tomoyuki; Ishii, Osamu; Kaazempur-Mofrad, Mohammad Reza; Borenstein, Jeffrey T.; King, Kevin R.; Wang, Chiao-Chun; Weinberg, Eli, Fabrication of vascularized tissue using microfabricated two-dimensional molds.
  44. Lundell,Beverley I.; Meisch,Robert L.; Wilson,John R.; Weston,Matthew W.; Mirsch, II,M. William; Grossinger, legal representative,Kathy J.; Page, deceased,Doug A., Flow system for medical device evaluation and production.
  45. Purchio Anthony F. ; New Liguo ; Liu Kang ; Kamali Vafa ; Naughton Brian, Gene up-regulated in regenerating liver.
  46. Mineau-Hanschke Rochelle, Hybrid matrix implants and explants.
  47. Mineau-Hanschke, Rochelle, Hybrid matrix implants and explants.
  48. Rochelle Mineau-Hanschke, Hybrid matrix implants and explants.
  49. Rochelle Mineau-Hanschke, Hybrid matrix implants and explants.
  50. Koob, Thomas J., Implantable collagen devices and related methods and systems of making same.
  51. Masini, Michael A.; Bancroft, Martin S., In vitro mechanical loading of musculoskeletal tissues.
  52. Mitrani, Eduardo N., In vitro micro-organs, and uses related thereto.
  53. Naughton Gail K. ; Naughton Brian A., In vitro preparation of tubular tissue structures by stromal cell culture on a three-dimensional framework.
  54. Smith Daniel J. ; Roselle Dominick, Lipophilic polyamine esters for the site specific delivery of nitric oxide in pharmaceutical use.
  55. Pearlman, Andrew L.; Stern, Baruch S., Long lasting drug formulations.
  56. Pearlman, Andrew L.; Stern, Baruch S., Long lasting drug formulations.
  57. Pearlman, Andrew L.; Stern, Baruch S., Long lasting drug formulations.
  58. Pearlman, Andrew L.; Stern, Baruch S., Long lasting drug formulations.
  59. Pearlman, Andrew L.; Stern, Baruch S., Long lasting drug formulations.
  60. Pearlman, Andrew; Stern, Baruch S., Long lasting drug formulations.
  61. McDaniel, David H., Low intensity light therapy for the manipulation of fibroblast, and fibroblast-derived mammalian cells and collagen.
  62. McDaniel, David H., Low intensity light therapy for treatment of retinal, macular, and visual pathway disorders.
  63. Naughton, Gail K.; Ziegler, Frank; Baumgartner, Mark; Nickey, Kyle, Low oxygen tension and BFGF generates a multipotent stem cell from a fibroblast in vitro.
  64. McDaniel,David H., Method and apparatus for acne prevention.
  65. McDaniel, David H., Method and apparatus for acne treatment.
  66. McDaniel,David H., Method and apparatus for acne treatment.
  67. McDaniel, David H., Method and apparatus for acne treatment using low intensity light therapy.
  68. McDaniel, David H., Method and apparatus for skin treatment.
  69. McDaniel, David H., Method and apparatus for skin treatment.
  70. McDaniel, David H., Method and apparatus for the photomodulation of living cells.
  71. Naughton Brian A. ; Halberstadt Craig R. ; Sibanda Benson, Method for culturing three-dimensional tissue in diffusion gradient bioreactor and use thereof.
  72. Termin, Paul L.; Carr, Jr., Robert M.; Condon, Kimberlie D., Method for treating diseased or damaged organs.
  73. Barofsky,Andrew D.; Gregory,Kenton W., Method for using tropoelastin and for producing tropoelastin biomaterials.
  74. Chu, Benjamin; Hsiao, Benjamin S.; Hadjiargyrou, Michael; Fang, Dufei; Zong, Xinhua; Kim, Kwangsok, Method of cell storage in a delivery system comprising a fibrous matrix.
  75. Vacanti, Joseph P.; Rubin, Robert; Cheung, Wing; Borenstein, Jeffrey T., Method of determining metabolism of a test agent.
  76. Vacanti, Joseph P.; Rubin, Robert; Cheung, Wing; Borenstein, Jeffrey T., Method of determining toxicity with three dimensional structures.
  77. Abraham,Ginger A.; Sullivan,Susan J.; Murray,James, Method of making a bioremodelable vascular graft prosthesis.
  78. Abraham,Ginger A.; Murray,James; Bachrach,Nathaniel M., Method of preparing layered graft prostheses.
  79. Fofonoff Timothy W. ; Bell Eugene, Methods and apparatus for the conditioning of ligament replacement tissue.
  80. Saito,Norimitsu; Zhao,Ming, Methods for introducing genes into mammalian subjects.
  81. Naughton Gail K., Methods for production of a naturally secreted extracellular matrix.
  82. Naughton, Gail K.; Mansbridge, Jonathan Noel; Pinney, Robert Emmett; Zeltinger, Joan, Methods for using a three-dimensional stromal tissue to promote angiogenesis.
  83. Mitrani,Eduardo N., Methods of generating tissue using devitalized, acellular scaffold matrices derived from micro-organs.
  84. Koob, Thomas J., Methods of making implantable collagen fiber.
  85. Vacanti, Joseph P.; Borenstein, Jeffrey T.; Weinberg, Eli, Microfabricated compositions and processes for engineering tissues containing multiple cell types.
  86. Borenstein, Jeffrey T.; Weinberg, Eli; Orrick, Brian K.; Pritchard, Eleanor M.; Barnard, Edward J.; Krebs, Nicholas J.; Marentis, Theodore; Vacanti, Joseph P.; Kaazempur-Mofrad, Mohammad Reza, Micromachined bilayer unit for filtration of small molecules.
  87. Borenstein, Jeffrey T.; Weinberg, Eli; Orrick, Brian K.; Pritchard, Eleanor M.; Barnard, Edward J.; Krebs, Nicholas J.; Marentis, Theodore; Vacanti, Joseph P.; Kaazempur-Mofrad, Mohammad Reza, Micromachined bilayer unit of engineered tissues.
  88. McDaniel, David H., Photomodulation methods and devices for regulating cell proliferation and gene expression.
  89. Bakkar, Khalid; Asselineau, Daniel, Pigmentable epidermis equivalent prepared from matrix cells and methods for the production thereof.
  90. Williams,Stuart K.; Hoying,James B.; Shepherd,Benjamin R., Prevascularized contructs for implantation to provide blood perfusion.
  91. Axel Haverich DE; Theo Kofidis DE, Process for producing a vascularized bioartificial tissue and an experimental reactor for carrying out the process.
  92. Haverich, Axel; Kofidis, Theo, Process for producing a vascularized bioartificial tissue and an experimental reactor for carrying out the process.
  93. McDaniel, David, Process for stimulating hair growth.
  94. McDaniel, David, Process for treatment of psoriasis.
  95. Auger Franois A. (Quebec CAX) L\Heureux Nicolas (Quebec CAX) Germain Lucie (Quebec CAX), Production of a contractile smooth muscle.
  96. McDaniel David H., Reduction, elimination, or stimulation of hair growth.
  97. Naughton, Gail K.; Ziegler, Frank; Baumgartner, Mark; Nickey, Kyle, Repair and/or regeneration of cells with a composition produced by culturing fibroblast cells under hypoxic conditions.
  98. Naughton, Gail K.; Ziegler, Frank; Baumgartner, Mark; Nickey, Kyle, Soluble composition for promoting hair growth produced by hypoxic culture of fibroblasts cells.
  99. Badylak Stephen F. ; Voytik Sherry ; Boder George, Submucosa gel as a growth substrate for cells.
  100. McDaniel, David H., System and method for the photodynamic treatment of burns, wounds, and related skin disorders.
  101. Breuer, Christopher; Snyder, Edward L.; Shafi, Keru O.; Smith, Martin A., System for seeding cells onto three dimensional scaffolds.
  102. Klausner, Mitchell; Ayehunie, Seyoum; Kubilus, Joseph, Three dimensional vaginal tissue model containing immune cells.
  103. Purchio Anthony F. ; Zimber Michael ; Dunkelman Noushin ; Naughton Gail K. ; Naughton Brian A., Three-dimensional cartilage cultures.
  104. Naughton Gail K. ; Naughton Brian A., Three-dimensional culture of pancreatic parenchymal cells cultured living stromal tissue prepared in vitro.
  105. Naughton Gail K. ; Naughton Brian A., Three-dimensional filamentous tissue having tendon or ligament function.
  106. Naughton Gail K. ; Naughton Brian A., Three-dimensional stromal tissue cultures.
  107. Atala, Anthony; Yoo, James J., Tissue engineered female reproductive organs.
  108. Atala,Anthony; Yoo,James J., Tissue engineered uterus.
  109. Atala,Anthony; Yoo,James J., Tissue engineered uterus.
  110. Gruber, James Vincent; Rao, Smitha; Mehta, Rahul; Sonti, Sujatha, Topical composition.
  111. David H. McDaniel, Ultrasound enhancement of percutaneous drug absorption.
  112. McDaniel David H., Ultrasound enhancement of percutaneous drug absorption.
  113. McDaniel,David H., Ultrasound enhancement of percutaneous drug absorption.
  114. Kuri-Harcuch, Walid; Castro Munozledo, Federico; Salazar-Olivio, Luis; Marsch-Moreno, Meytha, Wound repair dressings and methods for their preservation.

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