$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Method of preparing medical aerosol formulations including drug dissolved in reverse micelles 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/12
출원번호 US-0828195 (1992-01-30)
발명자 / 주소
  • Evans Richard M. (Norwood MA) Farr Stephen J. (Cardiff GB7)
출원인 / 주소
  • University of Wales College of Cardiff (Cardiff GBX 03)
인용정보 피인용 횟수 : 72  인용 특허 : 0

초록

The present invention provides a method for the production of medicinal aerosol compositions which are made up of a homogenous solution of aerosol propellants, a surfactant and a pharmaceutically active compound, where the process comprises purifying the surfactant, removing the water from the surfa

대표청구항

A method of preparing an aerosol formulation for drug delivery to a patient\s lungs, comprising the steps of: drying a surfactant from which reverse micelles can be formed; and mixing said surfactant with a drug, an amount of water, and a propellant to form reverse micelles of said surfactant in sai

이 특허를 인용한 특허 (72)

  1. Hale, Ron L.; Lei, Mingzu; Lloyd, Peter M.; Munzar, Patrik; Sharma, Krishnamohan; Solas, Dennis W.; Stracker, Matthew D., Aerosol drug delivery device incorporating percussively activated heat packages.
  2. Hodges, Craig C.; Lloyd, Peter M.; Mufson, Daniel; Rogers, Daniel D.; Wensley, Martin J., Aerosol forming device for use in inhalation therapy.
  3. Pankaj Modi CA, Aerosol formulations for buccal and pulmonary application.
  4. Wensley, Martin J.; Mufson, Daniel; Hodges, Craig C.; Lloyd, Peter M.; Rogers, Daniel D., Aerosol generating method and device.
  5. Wensley, Martin J.; Mufson, Daniel; Hodges, Craig C.; Lloyd, Peter M.; Rogers, Daniel D., Aerosol generating method and device.
  6. Chaudry, Imtiaz; Banerjee, Partha, Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease.
  7. Chaudry, Imtiaz; Banerjee, Partha, Albuterol inhalation solution, system, kit and method for relieving symptoms of pediatric asthma.
  8. Saidi Zahir ; Klyashchitsky Boris, Aqueous compositions containing corticosteroids for nasal and pulmonary delivery.
  9. Saidi, Zahir; Klyashchitsky, Boris, Aqueous compositions containing corticosteroids for nasal and pulmonary delivery.
  10. Trevino Leo A. (San Diego CA) Dellamary Luis A. (San Marcos CA) Tarara Thomas E. (San Diego CA) Weers Jeffry G. (San Diego CA) Ranney Helen M. (La Jolla CA), Continuous fluorochemical microdispersions for the delivery of lipophilic pharmaceutical agents.
  11. Rabinowitz, Joshua D.; Zaffaroni, Alejandro C., Delivery of antidepressants through an inhalation route.
  12. Rabinowitz,Joshua D.; Zaffaroni,Alejandro C., Delivery of antidepressants through an inhalation route.
  13. Rabinowitz,Joshua D.; Zaffaroni,Alejandro C., Delivery of antidepressants through an inhalation route.
  14. Rabinowitz,Joshua D; Zaffaroni,Alejandro C, Delivery of antidepressants through an inhalation route.
  15. Every, Nathan R.; Hale, Ron L.; Lu, Amy T.; Rabinowitz, Joshua D., Diuretic aerosols and methods of making and using them.
  16. Hale, Ron L.; Hodges, Craig C.; Lloyd, Peter M.; Lu, Amy T.; Myers, Daniel J.; Rabinowitz, Joshua D.; Wensley, Martin J.; McKinney, Jeffrey A.; Zaffaroni, Alejandro C., Drug condensation aerosols and kits.
  17. Hale, Ron L.; Hodges, Craig C.; Lloyd, Peter M.; Lu, Amy T.; Myers, Daniel J.; Rabinowitz, Joshua D.; Wensley, Martin J.; McKinney, Jeffrey A.; Zaffaroni, Alejandro C., Drug condensation aerosols and kits.
  18. Hale, Ron L.; Hodges, Craig C.; Lloyd, Peter M.; Lu, Amy T.; Myers, Daniel J.; Rabinowitz, Joshua D.; Wensley, Martin J.; McKinney, Jeffrey A.; Zaffaroni, Alejandro C., Drug condensation aerosols and kits.
  19. Hale,Ron L.; Hodges,Craig C.; Lloyd,Peter M.; Lu,Amy T.; Myers,Daniel J.; Rabinowitz,Joshua D.; Wensley,Martin J., Drug condensation aerosols and kits.
  20. Weers Jeffry G. ; Dellamary Luis A. ; Tarara Thomas E. ; Trevino Leo A. ; Ranney Helen M., Fluorochemical solutions for the delivery of lipophilic pharmaceutical agents.
  21. Mullen, Elaine H., Glycoprotein vesicles and their methods of use.
  22. Bomberger,David C.; Catz,Paul G.; Smedley,Mark I.; Stearns,Paul C., ICAM-1 formulation having controlled-size microparticles.
  23. Hale, Ron L.; Song, Soonho; Quintana, Reynaldo J.; Rabinowitz, Joshua D.; Zaffaroni, Alejandro C., Method and apparatus for vaporizing a compound.
  24. Hale,Ron L.; Song,Soonho; Quintana,Reynaldo J.; Zaffaroni,Alejandro C.; Rabinowitz,Joshua D., Method and apparatus for vaporizing a compound.
  25. Murdock Robert W. ; Williams C. Donald, Method and composition for transdermal administration of pharmacologic agents.
  26. Bomberger David C. ; Catz Paul G. ; Smedley Mark I. ; Stearns Paul C., Method for producing drug-loaded microparticles and an ICAM-1 dosage form so produced.
  27. Hale, Ron L.; Hodges, Craig C.; Lloyd, Peter M.; Mufson, Daniel; Rogers, Daniel D.; Song, Soonho; Wensley, Martin J.; Myers, Daniel J.; McKinney, Jeffrey A.; Quintana, Reynaldo J.; Rabinowitz, Joshua D., Method of forming an aerosol for inhalation delivery.
  28. Hale, Ron L.; Hodges, Craig C.; Lloyd, Peter M.; Mufson, Daniel; Rogers, Daniel D.; Song, Soonho; Wensley, Martin J.; Myers, Daniel J.; McKinney, Jeffrey A.; Quintana, Reynaldo J.; Rabinowitz, Joshua D., Method of forming an aerosol for inhalation delivery.
  29. Hale, Ron L.; Hodges, Craig C.; Lloyd, Peter M.; Mufson, Daniel; Rogers, Daniel D.; Song, Soonho; Wensley, Martin J.; Myers, Daniel J.; McKinney, Jeffrey A.; Quintana, Reynaldo J.; Rabinowitz, Joshua D., Method of forming an aerosol for inhalation delivery.
  30. Hale, Ron L.; Hodges, Craig C.; Lloyd, Peter M.; Mufson, Daniel; Rogers, Daniel D.; Song, Soonho; Wensley, Martin J.; Myers, Daniel J.; McKinney, Jeffrey A.; Quintana, Reynaldo J.; Rabinowitz, Joshua D., Method of forming an aerosol for inhalation delivery.
  31. Cook, Robert O.; Shrewsbury, Stephen B.; Ramadan, Nabih N.; Armer, Thomas A., Method of therapeutic administration of DHE to enable rapid relief of migraine while minimizing side effect profile.
  32. Cook, Robert O.; Shrewsbury, Stephen B.; Ramadan, Nabih N.; Armer, Thomas A., Method of therapeutic administration of DHE to enable rapid relief of migraine while minimizing side effect profile.
  33. Cook, Robert O.; Shrewsbury, Stephen B.; Ramadan, Nabih N.; Armer, Thomas A., Method of therapeutic administration of DHE to enable rapid relief of migraine while minimizing side effect profile.
  34. Cook, Robert O.; Shrewsbury, Stephen B.; Ramadan, Nabih N.; Armer, Thomas A., Method of therapeutic administration of DHE to enable rapid relief of migraine while minimizing side effect profile.
  35. Cook, Robert O.; Shrewsbury, Stephen B.; Ramadan, Nabih N.; Armer, Thomas A., Method of therapeutic administration of DHE to enable rapid relief of migraine while minimizing side effect profile.
  36. Murdock, Robert W.; Williams, C. Donald, Methods and transdermal compositions for pain relief.
  37. Robert W. Murdock ; C. Donald Williams, Methods and transdermal compositions for pain relief.
  38. Modi,Pankaj, Methods of administering and enhancing absorption of pharmaceutical agents.
  39. Modi Pankaj,CAX, Mixed liposome pharmaceutical formulation with amphiphiles and phospholipids.
  40. Pankaj Modi CA, Mixed micellar drug deliver system and method of preparation.
  41. Meyer, Adam; Schmidt, James; Dobson, Chris; Engelbreth, Daniel, Modular aerosol delivery system.
  42. Cross, Stephen D.; Herbette, Mathieu; Kelly, Andrew J. G.; Myers, Daniel J.; Shen, William W.; Timmons, Ryan D.; Tom, Curtis; Virgili, Justin M.; Wensley, Martin J., Multiple dose condensation aerosol devices and methods of forming condensation aerosols.
  43. Cross, Steven D.; Herbette, Mathieu; Kelly, Andrew J. G.; Myers, Daniel J.; Shen, William W.; Timmons, Ryan D.; Tom, Curtis; Virgili, Justin M.; Wensley, Martin J., Multiple dose condensation aerosol devices and methods of forming condensation aerosols.
  44. Klibanov, Alexander M., Nonaqueous solutions and suspensions of macromolecules for pulmonary delivery.
  45. Kordikowski, Andreas; Walker, Stephen Ernest; York, Peter, Particulate materials.
  46. Kordikowski, Andreas; Walker, Stephen Ernest; York, Peter, Particulate materials.
  47. Kordikowski, Andreas; Walker, Stephen Ernest; York, Peter, Particulate materials.
  48. Kordikowski, Andreas; Walker, Stephen Ernest; York, Peter, Particulate materials.
  49. Kordikowski, Andreas; Walker, Stephen Ernest; York, Peter, Particulate materials.
  50. Pankaj Modi CA, Pharmaceutical compositions for buccal and pulmonary administration comprising an alkali metal alkyl sulfate and at least three micelle-forming compounds.
  51. Pankaj Modi CA, Pharmaceutical compositions for buccal and pulmonary application.
  52. Modi, Pankaj, Pharmaceutical compositions for buccal delivery of pain relief medications.
  53. Modi Pankaj,CAX, Proteinic drug delivery system using aerosolized membrane-mimetic amphiphiles.
  54. Belloni, Paula Nanette; Jolidon, Synese; Klaus, Michael; Lapierre, Jean-Marc, RAR selective retinoid agonists.
  55. Hale, Ron L.; Lloyd, Peter M.; Lu, Amy; Myers, Daniel J.; Quintana, Reynaldo J.; Rabinowitz, Joshua D.; Solas, Dennis W.; Song, Soonho; Tom, Curtis; Wensley, Martin J., Rapid-heating drug delivery article and method of use.
  56. Damani, Ramesh; Hale, Ron L.; Myers, Daniel J.; Quintana, Reynaldo J.; Solas, Dennis W.; Song, Soonho; Soni, Pravin; Tom, Curtis; Sharma, Kirshnamohan, Self-contained heating unit and drug-supply unit employing same.
  57. Damani, Ramesh; Hale, Ron L.; Myers, Daniel J.; Quintana, Reynaldo J.; Solas, Dennis W.; Song, Soonho; Soni, Pravin; Tom, Curtis; Sharma, Krishnamohan, Self-contained heating unit and drug-supply unit employing same.
  58. Damani, Ramesh; Hale, Ron L.; Myers, Daniel J.; Quintana, Reynaldo J.; Solas, Dennis W.; Song, Soonho; Soni, Pravin; Tom, Curtis; Sharma, Krishnamohan, Self-contained heating unit and drug-supply unit employing same.
  59. Mullen, Elaine H., Sequestering of glycoprotein molecules and oligosaccharide moieties in lipo-glycoprotein membranes and micelles.
  60. Constantinides, Panayiotis P.; Liang, Likan; Jang, Eun-Hyun, Stabilized reverse micelle compositions and uses thereof.
  61. Schultz, Robert K.; Schultz, David W.; Oliver, Martin J.; Moris, Robert A.; Jinks, Philip A., Suspension aerosol formulations.
  62. Schultz,Robert K.; Schultz,David W.; Moris,Robert A., Suspension aerosol formulations.
  63. Schultz,Robert K.; Schultz,David W.; Moris,Robert A., Suspension aerosol formulations.
  64. Mullen, Elaine H., Synthetic membranes and micelle-like structures comprising lipo-glycoprotein membranes.
  65. David C. Bomberger ; Paul G. Catz ; Mark I. Smedley ; Paul C. Stearns, System and method for producing drug-loaded microparticles.
  66. Hale, Ron L.; Lu, Amy; Myers, Daniel J.; Rabinowitz, Joshua D.; Wensley, Martin J., Thin-film drug delivery article and method of use.
  67. Mazac Charles J. (West Lafayette IN) Rubacha John S. (West Lafayette IN), Uses of heptafluoropropane.
  68. Mazela, Jan; Henderson, Christopher, Ventilation circuit adaptor and proximal aerosol delivery system.
  69. Mazela, Jan; Henderson, Christopher, Ventilation circuit adaptor and proximal aerosol delivery system.
  70. Mazela, Jan; Henderson, Christopher, Ventilation circuit adaptor and proximal aerosol delivery system.
  71. Grychowski, Jerry R.; Foley, Martin P., Ventilator circuit and method for the use thereof.
  72. Grychowski, Jerry R.; Foley, Martin P., Ventilator circuit and method for the use thereof.
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로