[특허]Osmotically driven syringe with programmable agent delivery

Osmotically driven syringe with programmable agent delivery 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	A61K-009/22
출원번호	US-0863649 (1992-04-03)
발명자 / 주소	Theeuwes Felix (1634 Fallen Leaf La. Los Altos CA 94022) Yum Su Il (1021 Runnymead Ct. Los Altos CA 94022)
인용정보	피인용 횟수 : 78 인용 특허 : 0

초록 ▼

An osmotically driven syringe (20, 60) is disclosed which can be used to deliver a beneficial agent such as a drug, at varying pre-determined rates over multiple periods of time. The syringe (20, 60) is driven by an osmotic engine (10) having a shaped wall (12) containing an osmotic agent (17) and/or a gas generating means (19), such as an effervescent couple. The wall (12) is composed of a semipermeable and/or microporous material which is permeable to an external liquid (e.g., water) but which is substantially impermeable to the osmotic agent (17) and the gas generated by the gas generating means (19). The wall (12) has a passageway (13) therethrough to provide a flow path for the driving fluid generated by the engine (10). The osmotic agent(s) (17) and/or the gas generating means (19) are placed in the engine (10) in such a way as to drive engine (10) at different pumping rates (R1, R2) over sequential periods of time (t0 to t1 and t1 to t2).

대표청구항 ▼

An osmotic engine for driving a device adapted to dispense a beneficial agent, the engine comprising a shaped wall surrounding a means for forming a driving fluid and a passageway through the wall for delivering the driving fluid from the engine, at least a portion of the wall being comprised of a material that is permeable to an external liquid, the wall having a sufficient degree of impermeability to an osmotically active material in the engine to generate an osmotic pressure differential across the wall when the wall is exposed to the external liquid; wherein the means for forming a driving fluid comprises an osmotic solute which is soluble in the external liquid, whereby the external liquid permeates through the wall portion and forms a saturated solution of the solute, the saturated solution being a first driving fluid which is pumped from the engine and through the passageway at a first rate over a first period of time and subsequently the external liquid permeates through the wall portion and forms a subsaturated solution of the solute, the unsaturated solution being a second driving fluid which is pumped from the engine and through the passageway at a second rate over a second period of time which follows the first period of time, the second rate being unequal to the first rate.

이 특허를 인용한 특허 (78)

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Rohloff, Catherine M.; Chen, Guohua; Luk, Andrew S.; Ayer, Rupal A.; Houston, Paul R.; Desjardin, Michael A.; Zamora, Pauline; Lam, Stan, Solvent/polymer solutions as suspension vehicles.
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Rohloff, Catherine M.; Chen, Guohua; Luk, Andrew S.; Ayer, Rupal A.; Houston, Paul R.; Desjardin, Michael A.; Zamora, Pauline; Lam, Stan, Solvent/polymer solutions as suspension vehicles.
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Rohloff, Catherine M.; Chen, Guohua; Luk, Andrew S.; Ayer, Rupal A.; Houston, Paul R.; Desjardin, Michael A.; Zamora, Pauline; Lam, Stan, Solvent/polymer solutions as suspension vehicles.
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Rohloff, Catherine M.; Chen, Guohua; Luk, Andrew S.; Ayer, Rupal A.; Houston, Paul R.; Desjardin, Michael A.; Zamora, Pauline; Lam, Stan, Solvent/polymer solutions as suspension vehicles.
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IPC	Description
A	생활필수품
A62	인명구조; 소방(사다리 E06C)
A62B	인명구조용의 기구, 장치 또는 방법(특히 의료용에 사용되는 밸브 A61M 39/00; 특히 물에서 쓰이는 인명구조 장치 또는 방법 B63C 9/00; 잠수장비 B63C 11/00; 특히 항공기에 쓰는 것, 예. 낙하산, 투출좌석 B64D; 특히 광산에서 쓰이는 구조장치 E21F 11/00)
A62B-1/08	.. 윈치 또는 풀리에 제동기구가 있는 것

내보내기 구분	파일저장 인쇄 메일전송
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연합인증

Osmotically driven syringe with programmable agent delivery 원문보기

초록 ▼

대표청구항 ▼

연구과제 타임라인

이 특허를 인용한 특허 (78)

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연합인증

Osmotically driven syringe with programmable agent delivery 원문보기

초록 ▼

대표청구항 ▼

연구과제 타임라인

전체(0) 논문(0) 특허(0) 보고서(0)

전체(0) 논문(0) 특허(0) 보고서(0)

이 특허를 인용한 특허 (78)

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