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| 국가/구분 | United States(US) Patent 등록 |
|---|---|
| 국제특허분류(IPC7판) |
|
| 출원번호 | US-0900007 (1992-06-17) |
| 발명자 / 주소 |
|
| 출원인 / 주소 |
|
| 인용정보 | 피인용 횟수 : 553 인용 특허 : 0 |
Method and apparatus for treating severe chronic, persistent or recurring neuropathic or psychogenic pain, or pain which is nociceptive if the patient is suffering from terminal disease, by selectively applying a pulse waveform to a lead/electrode implanted on the patient\s cervical vagus nerve or o
Method and apparatus for treating severe chronic, persistent or recurring neuropathic or psychogenic pain, or pain which is nociceptive if the patient is suffering from terminal disease, by selectively applying a pulse waveform to a lead/electrode implanted on the patient\s cervical vagus nerve or other site preferably above the location of the pain to stimulate afferent fibers for activating a descending anti-nociceptive pathway and thereby blocking incoming pain signals. The pulse waveform has programmable pulse width, current level and frequency, and pulse sequence on and off time durations. The programmed pulse sequences are applied to the implanted electrode either on a continuous basis, or only during the period the patient is normally awake, or is initiated by the patient or automatically in response to the onset of pain. A method for use in advancing relief and control of pain includes providing the lead/electrode assembly to be implanted and the generator for the programmable pulse sequences, incorporating a connector on the generator to accommodate the lead, restricting the ranges of programmable values of the pulse sequences to values which in combination will stimulate the small afferent fibers of the vagus nerve to activate a descending anti-nociceptive pathway, and adapting the generator for physician selection of manner of control of commencement and cessation of the pulse sequences.
A method of treating patients suffering from chronic or persistent pain which is neuropathic or psychogenic, or which is nociceptive in the case of a patient with terminal disease, the method including the steps of: implanting a nerve electrode assembly at a distal end of an electrical lead on the v
A method of treating patients suffering from chronic or persistent pain which is neuropathic or psychogenic, or which is nociceptive in the case of a patient with terminal disease, the method including the steps of: implanting a nerve electrode assembly at a distal end of an electrical lead on the vagus nerve of the patient, implanting a stimulus generator in the patient\s body for generating an output signal with variable electrical waveform parameters programmable externally of the body, and electrically connecting the generator to a proximal end of the lead internally of the patient to enable the generator, when activated, to selectively deliver a programmed electrical signal having predetermined electrical waveform parameters as a stimulus directly to the patient\s vagus nerve via the implanted nerve electrode assembly for modulating electrical activity of the nerve to stimulate afferent fibers thereof and alleviate the pain under treatment, and selectively activating the generator to alleviate the pain under treatment.
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