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[미국특허] Composition and process for gelatin-free soft capsules 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/62
출원번호 US-0053578 (1993-04-27)
발명자 / 주소
  • Winston
  • Jr. Philip E. (San Diego CA) Miskiel Frank J. (San Diego CA) Valli Raymond C. (San Diego CA)
출원인 / 주소
  • Merck & Co., Inc. (Rahway NJ 02)
인용정보 피인용 횟수 : 52  인용 특허 : 0

초록

The present invention relates to a polymer composition comprised of gellan, carrageenan and mannan gums and a process for producing flexible films for encapsulation comprising the gellan, carrageenan and mannan gum composition. The mannan gums include the galactomannans and the glucomannans. Advanta

대표청구항

A gelatin-free soft capsule comprising from 1 to 10 weight percent of a gum-blend composition which comprises a gellan gum: (carrageenan gum/mannan gum) wherein the gellan gum concentration ranges from about 0.1 to 50 weight percent and the ratio of carrageenan/mannan gum ranges from 3:1 to 1:3 and

이 특허를 인용한 특허 (52)

  1. Petkovich, P. Martin; Melnick, Joel Z.; White, Jay A.; Tabash, Samir P.; Bishop, Charles W.; Peers, Susan; Strugnell, Stephen A., Adjunctive therapy with 25-hydroxyvitamin D and articles therefor.
  2. Verma Surendra Kumar ; Jarrell Michael Scott, Alkylene oxide polymer compositions.
  3. Paris Laurence,FRX ; Viaud Fabrice,FRX, Aqueous viscous compositions, whether clear or not, for making soft or hard capsules, and method for making films for such capsules.
  4. Chantranukul,Arjnarong; Xiao,Chaodong; Li,Zhixin; Chakrabarti,Sibu; Okoniewska,Monika K., Blends of different acyl gellan gums and starch.
  5. Li, Shun-Por; Lee, Der-Yang; Bunick, Frank J.; Chen, Jen Chi; Sowden, Harry S., Burst-release polymer composition and dosage forms comprising the same.
  6. Draisey, Allan, Capsules.
  7. Glidden, Paul F.; Pilgrim, Alison J.; Hanson, Stephen R., Controlled release compositions of agents that reduce circulating levels of platelets and methods therefor.
  8. Glidden, Paul F.; Pilgrim, Alison J.; Hanson, Stephen R., Controlled release compositions of agents that reduce circulating levels of platelets and methods therefor.
  9. Nussinovitch, Amos, Encapsulating liquid with hydrocolloid membrane stable from about -20 to 90 degrees C without bursting.
  10. Keith Edward Tanner ; Peter Robert Draper CA; John J. Getz ; Stephen W. Burnett ; Elizabeth Youngblood, Film forming compositions comprising modified starches and iota-carrageenan and methods for manufacturing soft capsules using same.
  11. Tanner, Keith Edward; Getz, John J.; Burnett, Stephen W.; Youngblood, Elizabeth; Draper, Peter Robert, Film forming compositions comprising modified starches and iota-carrageenan and methods for manufacturing soft capsules using same.
  12. Tanner,Keith Edward; Draper,Peter Robert; Getz,John J.; Burnett,Stephen W.; Youngblood,Elizabeth, Film forming compositions comprising modified starches and iota-carrageenan and methods for manufacturing soft capsules using same.
  13. Grazela, Andrew J; Morrison, Neil Argo, Gelatin-free gummy confection using gellan gum and carrageenan.
  14. Palaniappan, Ravi, Gellan-gum nanoparticles and methods of making and using the same.
  15. Jacobs, Irwin; Gee, Stephen; Brady, Paul, Gelling agent-based dosage form.
  16. Sewall, Christopher J.; Riley, Peter J.; Blakemore, William R., Homogeneous, thermoreversible gel containing reduced viscosity carrageenan and products made therefrom.
  17. Modliszewski, James J.; Ballard, Arthur D.; Sewall, Christopher J.; Blakemore, William R.; Riley, Peter J., Homogeneous, thermoreversible gel film containing kappa-2 carrageenan and soft capsules made therefrom.
  18. Caswell, Debra Sue; Welch, Robert Gary; Ridyard, Mark William; Sayers, Edward; York, David William; Dufton, Daniel James; Howe, Simon; Eshuis, Johan; Pena Romero, Angelina; Laudamiel Pellet, Christophe; Hoffmann, Wundriari; Deckner, George Endel; Wahl, Errol Hoffman; Murphy, Ruth Anne; Hensley, legal representative, Betty J.; Trinh, Toan; Dihora, Jiten Odhavji; Baker, Ellen Schmidt; Littig, Janet Sue; Schroeder, Timothy James; Diersing, Steven Louis; Dodd, Malcolm McClaren; Gallon, Lois Sara; Hensley, Charles Albert, Laundry system having unitized dosing.
  19. Woiszwillo James E. ; Brown Larry R. ; Scott Terrence L. ; Di Jie ; Sudhalter Judith ; Blizzard Charles D., Macromolecular microparticles and methods of production and use.
  20. Woiszwillo James E. ; Brown Larry R. ; Scott Terrence L. ; Di Jie ; Sudhalter Judith ; Blizzard Charles D. ; Riske Frank J., Macromolecular microparticles and methods of production and use.
  21. Woiszwillo James E. ; Brown Larry R. ; Scott Terrence L. ; Di Jie ; Sudhalter Judith ; Blizzard Charles D. ; Riske Frank J., Macromolecular microparticles and methods of production and use.
  22. Bishop, Charles W.; Tabash, Samir P.; Agudoawu, Sammy A.; White, Jay A.; Messner, Eric J.; Petkovich, P. Martin; Crawford, Keith H., Method for controlled release oral dosage of a vitamin D compound.
  23. Sowden, Harry S.; Plantz, Bernard F.; Li, Shun Por, Method for manufacturing dosage forms.
  24. Ishikawa, Nobuyuki; Kajima, Koji; Yamada, Yasunori; Akaike, Tusue, Method for manufacturing soft capsule and apparatus for manufacturing the same.
  25. Bishop, Charles W.; Tabash, Samir P.; Agudoawu, Sammy A.; White, Jay A.; Crawford, Keith H.; Messner, Eric J.; Petkovich, P. Martin, Method for treating secondary hyperparathyroidism in CKD.
  26. Bishop, Charles W.; Tabash, Samir P.; Agudoawu, Sammy A.; White, Jay A.; Messner, Eric J.; Petkovich, P. Martin; Crawford, Keith H., Method for treating secondary hyperparathyroidism in CKD.
  27. Sowden, Harry S.; Plantz, Bernard F.; Li, Shun Por, Method of coating a dosage form comprising a first medicant.
  28. Bishop, Charles W.; Tabash, Samir P.; Agudoawu, Sammy A.; White, Jay A.; Crawford, Keith H.; Messner, Eric J.; Petkovich, P. Martin, Methods for controlled release oral dosage of a vitamin D compound.
  29. Wynn, David; McNally, Gerard P.; Sowden, Harry S., Modified release dosage form.
  30. Gregory M. Gilleland ; Judy L. Turner ; Penelope A. Patton ; Michael D. Harrison, Modified starch as a replacement for gelatin in soft gel films and capsules.
  31. Fonkwe, Linus G.; Archibald, Don A.; Gennadios, Aristippos, Non-gelatin capsule shell formulation.
  32. Fang, Qi; Heflin, Josh; Hariharan, Madhu, Non-gelatin enteric soft capsules.
  33. Fang, Qi; Heflin, Josh; Hariharan, Madhu, Non-gelatin enteric soft capsules.
  34. Archibald, Don A.; Fang, Qi; Fonkwe, Linus G.; Dietel, Gregory L.; Casault, Charles S., Non-gelatin film and method and apparatus for producing same.
  35. Gennadios Aristippos, Non-gelatin substitutes for oral delivery capsules, their composition and process of manufacture.
  36. Sedmak, Joseph James, Production of beta-glucans and mannans.
  37. Tsai, Albert G.; Ledwith, Linnea K. S.; Kopesky, Robert; Lynch, Maurice Gerard; Blakemore, William Ross; Riley, Peter J., Production of carrageenan and carrageenan products.
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  39. Anfinsen, Jon R.; Tungland, Bryan Craig, Reduced digestible carbohydrate food having reduced blood glucose response.
  40. Hartmann, Didier; Hannetel, Jean-Michel; Coursieres, Nathalie; Mane, Jean, Smoking device incorporating a breakable capsule, breakable capsule and process for manufacturing said capsule.
  41. Hartmann, Didier; Hannetel, Jean-Michel; Coursieres, Nathalie; Mane, Jean, Smoking device incorporating a breakable capsule, breakable capsule and process for manufacturing said capsule.
  42. Angel, Maximilian; Kolter, Karl; Sanner, Axel; Gotsche, Michael, Soft capsules comprising polymers of vinyl esters and polyethers, the use and production thereof.
  43. Roulier Veronique,FRX ; Quemin Eric,FRX, Solid cosmetic composition and uses thereof.
  44. Roulier, Veronique; Quemin, Eric, Solid cosmetic composition and uses thereof.
  45. White, Jay A.; Tabash, Samir P.; Agudoawu, Sammy A.; Melnick, Joel Z., Stabilized modified release vitamin D formulation and method of administering same.
  46. Muller, Rolf; Innerebner, Federico, Starch foils and/or films and a method and use of a device for the production thereof.
  47. Muller, Rolf; Innerebner, Federico, Starch foils and/or films and a method and use of a device for the production thereof.
  48. Nussinovitch Amos,ILX, Temperature-stable liquid cells.
  49. Bishop, Charles W.; Crawford, Keith H.; Messner, Eric J., Treating vitamin D insufficiency and deficiency with 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3.
  50. Bishop, Charles W.; Crawford, Keith H.; Messner, Eric J., Treating vitamin D insufficiency and deficiency with 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3.
  51. Yan, Cuie; Zhang, Wei; Jin, Yulai; Demont, Lesek Alexa; Barrow, Colin James, Vegetarian microcapsules.
  52. Perkins, Gary, Water leak detection.

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