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Transglutaminase cross-linkable polypeptides and methods relating thereto 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-038/00
  • C07K-005/00
  • C07K-007/00
  • C07K-017/00
출원번호 US-0106509 (1993-08-13)
발명자 / 주소
  • Labroo Virender (Mill Creek WA) Busby Sharon J. (Seattle WA)
출원인 / 주소
  • ZymoGenetics, Inc. (Seattle WA 02)
인용정보 피인용 횟수 : 55  인용 특허 : 0

초록 ▼

Polypeptides of from 3-120 amino acid residues comprising a segment of the formula Gln-Y-Lys, wherein Y is a spacer peptide of 1 to 12, wherein said polypeptides are cross-linkable by a transglutaminase, homo- and copolymers containing such polypeptides are disclosed. The homo- and co-polymers discl

대표청구항 ▼

A polypeptide of from 13-120 amino acid residues, said polypeptide comprising a segment having the formula S1－Y－S2, wherein: S1 is Thr-Ile-Gly-Glu-Gly-Gln (SEQ ID NO: 12); Y is a spacer peptide of 1-7 amino acids or not present; and S2 is Xaa-Lys-Xaa-Ala-Gly-Asp-Val (SEQ ID NO: 13), wherein said pol

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