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Peptide library and screening systems 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12Q-001/70
출원번호 US-0718577 (1991-06-20)
발명자 / 주소
  • Dower William J. (Menlo Park CA) Cwirla Steven E. (Palo Alto CA) Barrett Ronald W. (Sunnyvale CA)
출원인 / 주소
  • Affymax Technologies N.V. (NLX 03)
인용정보 피인용 횟수 : 167  인용 특허 : 0

초록 ▼

Peptides which bind to selected receptors are identified by screening libraries which encode a random or controlled collection of amino acids. Peptides encoded by the libraries are expressed as fusion proteins of bacteriophage coat proteins, and bacteriophage are then screened against the receptors

대표청구항 ▼

A method for obtaining a bacteriophage encoding a substrate cleaved by a preselected proteolytic enzyme, comprising: (a) transforming host cells with at least 106 different bacteriophage expression vectors, wherein each of said vectors encodes a fusion protein composed of a random peptide fused to a

이 특허를 인용한 특허 (167)

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