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Digital analyte detection system 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • G06G-007/75
출원번호 US-0243153 (1994-05-16)
발명자 / 주소
  • Allen Fritz (Corrales NM) Niemczyk Thomas (Albuquerque NM)
출원인 / 주소
  • Acrogen, Inc. (Oakland CA 02)
인용정보 피인용 횟수 : 60  인용 특허 : 0

초록

A system and method for digitally detecting the presence of analyte particles within a sample is disclosed herein. Each analyte particle is disposed to emit an optical response upon illumination in a known manner. The digital analyte detection system includes optical apparatus for illuminating a mul

대표청구항

A method for detecting the presence of a small number of analyte particles within a sample, said sample being divided into a multiplicity of distinct pixel regions where light emitted in each of said pixel regions is related to the amount of analyte in each of said pixel regions, comprising the step

이 특허를 인용한 특허 (60)

  1. Seul, Michael; Xia, Xiongwu; Chau, Chiu; Determan, Scott, Analysis, secure access to, and transmission of array images.
  2. Xia, Xiongwu; Seul, Michael; Chau, Chiu; Determan, Scott, Analysis, secure access to, and transmission of array images.
  3. Banerjee, Sukanta; Seul, Michael; Li, Alice X., Arrays of magnetic particles.
  4. Xia, Xiongwu; Seul, Michael, Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification.
  5. Geysen H. Mario ; Nelson James C. ; Buckner Charles, Bead picking apparatus and method.
  6. Banerjee, Sukanta; Yang, Jiacheng; Seul, Michael, Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation.
  7. Duffy, David C.; Song, Linan; Shan, Dandan; Zhao, Mingwei, Detection of DNA or RNA using single molecule arrays and other techniques.
  8. Olesen, Tom, Flexible sample container.
  9. Richards, William L.; Ashby, Austin; Ketterer, Matthew; Marshall, Kevin; Harrison, Josh; Mette, Matthew; Richards, Paul; Showalter, Wayne; Cote, Jasmin; Halbert, Phillip C.; Bourgeois, Solene; Metzger, Steven W.; Hance, Ken; Mensack, Meghan; Michel, Carlos; Allers, Elke; Gamage, Dulini; Prisbrey, Landon; Gusyatin, Oleg; Shamsheyeva, Alena; Turng, Ben; Ghusson, Andrew; Reinhardt, Kurt, Instrument and system for rapid microogranism identification and antimicrobial agent susceptibility testing.
  10. Richards, William L.; Ashby, Austin; Ketterer, Matthew; Marshall, Kevin; Harrison, Josh; Mette, Matthew; Richards, Paul; Showalter, Wayne; Cote, Jasmin; Halbert, Phillip C.; Bourgeois, Solene; Metzger, Steven W.; Hance, Ken; Mensack, Meghan; Michel, Carlos; Allers, Elke; Gamage, Dulini; Prisbrey, Landon; Gusyatin, Oleg; Shamsheyeva, Alena; Turng, Ben; Ghusson, Andrew; Reinhardt, Kurt, Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing.
  11. Worthington, Mark Oscar; Virtanen, Jorma Antero; Pal, Andrew Attila, Interactive system for analyzing biological samples and processing related information and the use thereof.
  12. Yang, Jiacheng, Kits for multiplexed nucleic acid analysis by capture of single-stranded DNA produced from double-stranded target fragments.
  13. Prisbrey, Landon; Blackmore, Elise; Hance, Kenneth R.; Metzger, Steven W.; Marshall, Kevin, Membrane-assisted purification.
  14. Marks Andrew F., Method and apparatus for analysis of chromatographic migration patterns.
  15. Stephen Peter Fitzgerald GB; Robert Ivan McConnell GB; John Victor Lamont GB, Method and apparatus for analyzing an image.
  16. Vannah William M., Method and apparatus for recording three-dimensional topographies.
  17. Hammond, Jeremy; Russell, James, Method and device for detecting bacteria and determining the concentration thereof in a liquid sample.
  18. Seul, Michael, Method of making a microbead array with attached biomolecules.
  19. Seul, Michael, Method of making a microbead array with attached biomolecules.
  20. Walt, David R.; Rissin, David M., Methods and arrays for detecting cells and cellular components in small defined volumes.
  21. Walt, David R.; Rissin, David M.; Gorris, Hans-Heiner, Methods and arrays for target analyte detection and determination of reaction components that affect a reaction.
  22. Walt, David R.; Rissin, David M., Methods and arrays for target analyte detection and determination of target analyte concentration in solution.
  23. Walt, David R.; Rissin, David M., Methods and arrays for target analyte detection and determination of target analyte concentration in solution.
  24. Walt, David R.; Rissin, David M., Methods and arrays for target analyte detection and determination of target analyte concentration in solution.
  25. Rissin, David M.; Fournier, David; Duffy, David C., Methods and systems for extending dynamic range in assays for the detection of molecules or particles.
  26. Rissin, David M.; Fournier, David; Duffy, David C., Methods and systems for extending dynamic range in assays for the detection of molecules or particles.
  27. Rissin, David M.; Fournier, David; Duffy, David C., Methods and systems for extending dynamic range in assays for the detection of molecules or particles.
  28. Rissin, David M.; Fournier, David; Duffy, David C., Methods and systems for extending dynamic range in assays for the detection of molecules or particles.
  29. Worthington,Mark Oscar, Methods for detecting analytes using optical discs and optical disc readers.
  30. Walt, David R.; Rissin, David M., Methods for determining the concentration of an analyte in solution.
  31. Wang, Xinwen; Banerjee, Sukanta, Microparticles with enhanced covalent binding capacity and their uses.
  32. Krutzik,Siegfried Richard, Multi-purpose optical analysis optical bio-disc for conducting assays and various reporting agents for use therewith.
  33. Banerjee, Sukanta; Seul, Michael, Multianalyte molecular analysis using application-specific random particle arrays.
  34. Worthington,Mark O.; Norton,James R.; Kido,Horacio; Ortiz,Victor M., Multiple data layer optical discs for detecting analytes.
  35. Seul, Michael; Chau, Chiu Wo; Tan, Enqing, Number coding for identification of subtypes of coded types of solid phase carriers.
  36. Olesen, Tom; Valvik, Martin Christian; Larsen, Niels Agersnap; Sandberg, Rasmus Helmsby, Optical sectioning of a sample and detection of particles in a sample.
  37. Olesen, Tom; Valvik, Martin Christian; Larsen, Niels Agersnap; Sandberg, Rasmus Helmsby, Optical sectioning of a sample and detection of particles in a sample.
  38. Seul, Michael; Banerjee, Sukanta; Yang, Jiacheng; Vener, Tatiana, Optimization of gene expression analysis using immobilized capture probes.
  39. Seul, Michael; Banerjee, Sukanta; Yang, Jiacheng; Vener, Tatiana, Optimization of gene expression analysis using immobilized capture probes.
  40. Nikawa Kiyoshi,JPX, Parasitic MIM structural spot analysis method for semiconductor device and parasitic MIM structure spot analysis method for silicon semiconductor device.
  41. Lett, G. Scott; Haubein, Ned C.; Pestano, Gary, Quantitative, multispectral image analysis of tissue specimens stained with quantum dots.
  42. Metzger, Steven W.; Hance, Kenneth Robert, Rapid cell purification systems.
  43. Metzger, Steven W.; Hance, Kenneth Robert, Rapid cell purification systems.
  44. Metzger, Steven W.; Hance, Kenneth Robert, Rapid cell purification systems.
  45. Shamsheyeva, Alena; Howson, David C.; Metzger, Steven W., Rapid determination of microbial growth and antimicrobial susceptibility.
  46. Metzger, Steven W.; Howson, David C.; Goldberg, David A.; Buttry, Daniel A., Rapid microbial detection and antimicrobial susceptibility testing.
  47. Goldberg, David A.; Howson, David C.; Metzger, Steven W.; Buttry, Daniel A.; Saavedra, Steven Scott, Sensitive and rapid determination of antimicrobial susceptibility.
  48. Goldberg, David A.; Howson, David C.; Metzger, Steven W.; Buttry, Daniel A.; Saavedra, Steven Scott, Sensitive and rapid determination of antimicrobial susceptibility.
  49. Goldberg, David A.; Howson, David C.; Metzger, Steven W.; Buttry, Daniel A.; Saavedra, Steven Scott, Sensitive and rapid determination of antimicrobial susceptibility.
  50. Goldberg, David A.; Howson, David C.; Metzger, Steven W.; Buttry, Daniel A.; Saavedra, Steven Scott, Sensitive and rapid determination of antimicrobial susceptibility.
  51. Demers,James Paul, Spatially addressable combinatorial chemical arrays in encoded optical disk format.
  52. Olesen, Tom; Valvik, Martin Christian; Larsen, Niels Agersnap, System and method for time-related microscopy of biological organisms.
  53. Fournier, David; Campbell, Todd; Kan, Cheuk; Lawson, John; Rivnak, Andrew; Kagan, Michael; Duffy, David C., Systems, devices, and methods for ultra-sensitive detection of molecules or particles.
  54. Duffy, David C.; Ferrell, Evan; Randall, Jeffrey D.; Rissin, David M.; Walt, David R., Ultra-sensitive detection of molecules on single molecule arrays.
  55. Duffy, David C.; Ferrell, Evan; Randall, Jeffrey D.; Rissin, David M.; Walt, David R., Ultra-sensitive detection of molecules on single molecule arrays.
  56. Duffy, David C.; Rissin, David M.; Walt, David R.; Fournier, David; Kan, Cheuk, Ultra-sensitive detection of molecules or particles using beads or other capture objects.
  57. Duffy, David C.; Rissin, David M.; Walt, David R.; Fournier, David; Kan, Cheuk, Ultra-sensitive detection of molecules or particles using beads or other capture objects.
  58. Duffy, David C.; Rissin, David M.; Walt, David R.; Fournier, David; Kan, Cheuk, Ultra-sensitive detection of molecules or particles using beads or other capture objects.
  59. Duffy, David C.; Rissin, David M.; Walt, David R.; Song, Linan; Chang, Lei, Ultra-sensitive detection of molecules using dual detection methods.
  60. Seul, Michael; Banerjee, Sukanta; Podual, Kairali; Hong, Ye, Un-supported polymeric film with embedded microbeads.
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