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Antibiotic and cytotoxic drug susceptibility assays using resazurin and poising agents 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12Q-001/18
  • C12Q-001/02
  • C12N-005/02
  • C12N-001/02
출원번호 US-0396362 (1995-02-28)
발명자 / 주소
  • Lancaster Michael V. (Woodland CA) Fields Rebecca D. (Woodland CA)
출원인 / 주소
  • Alamar Biosciences Laboratory, Inc. (Chicago IL 02)
인용정보 피인용 횟수 : 41  인용 특허 : 0

초록 ▼

Growth inhibition assays for both microorganisms and mammalian cells are performed by incubating the microorganisms or cells in a growth medium in the presence of resazurin and a suspected growth inhibiting agent. By observing a color change accompanied by the reduction of resazurin to resorfurin, c

대표청구항 ▼

A method for determining susceptibility of cultured cells to growth inhibitory substances, said method comprising: culturing the cells in a growth medium in the presence of the growth inhibitory substance; exposing the cultured cells to resazurin in the presence of a poising agent in an amount selec

이 특허를 인용한 특허 (41)

  1. Huesca, Mario; Young, Aiping H.; Lee, Yoon; Khine, Aye Aye; Wright, Jim A.; Lock, Lisa; Al-Qawasmeh, Raed, 2-indolyl imidazo [4,5-d] phenanthroline derivatives and their use in the treatment of cancer.
    상세보기
  2. Lee, Yoon; Cukier, Howard; Nedunuri, Venkata; Peralta, Robert; Huesca, Mario; Young, Aiping H., 2-substituted imidazo[4,5-D]phenanthroline derivatives and their use in the treatment of cancer.
    상세보기
  3. Huesca, Mario; Al-Qawasmeh, Raed; Young, Aiping H.; Lee, Yoon; Lock, Lisa, Aryl imidazoles and their use as anti-cancer agents.
    상세보기
  4. Alexander W. Clark ; Paul Gladnick ; Robert E. Armstrong ; Nicholas Bachur ; Klaus W. Berndt ; Dwight Livingston, Automated microbiological testing apparatus and method therefor.
    상세보기
  5. Clark,Alexander W.; Gladnick,Paul; Armstrong,Robert E.; Bachur,Nicholas; Berndt,Klaus W.; Livingston,Dwight, Automated microbiological testing apparatus and method therefor.
    상세보기
  6. Clark Alexander W. ; Gladnick Paul ; Armstrong Robert E. ; Bachur Nicholas ; Berndt Klaus W. ; Livingston Dwight, Automated microbiological testing apparatus and methods therefor.
    상세보기
  7. Williams, Gregory B.; Nothaft, Daniel M.; Enscoe, Glenn F.; Burtner, Kathleen N.; Kangas, Monte E., Combined rapid susceptibility assay and microorganism identification system.
    상세보기
  8. Barry Bochner ; Eugenia Panomitros, Comparative phenotype analysis.
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  9. Bochner, Barry, Comparative phenotype analysis.
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  10. Bochner, Barry, Comparative phenotype analysis for assessment of biological active compounds such as antimicrobials.
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  11. Barry Bochner, Comparative phenotype analysis for assessment of biologically active compounds such as antimicrobials.
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  12. Barry Bochner ; Eugenia Panomitros, Comparative phenotype analysis of two or more microorganisms using a plurality of substrates within a microwell device.
    상세보기
  13. Bochner Barry, Comparative phenotype analysis of two or more microorganisms using a plurality of substrates within a multiwell testing device.
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  14. Bochner, Barry; Panomitros, Eugenia, Comparative phenotype analysis of two or more microorganisms using a plurality of substrates within a multiwell testing device.
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  15. Arab, Nicolas; Johnson, Ross, Compositions and methods for disease diagnosis using single cell analysis.
    상세보기
  16. Rice, William G., Compositions and methods for treating cancers.
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  17. Sharpin, Rosemary Katherine Cameron, Container for testing for micro-organisms.
    상세보기
  18. Riss,Terry L.; Moravec,Richard A., Cytotoxicity assay.
    상세보기
  19. Sullivan,Nadine Michele; Allen,Sara Elizabeth, Detection of microbiological growth in a sealed container using a poising agent.
    상세보기
  20. Black, Jennifer A.; Moland, Ellen S.; Thomson, Kenneth, Device and direct method for detecting antibiotic-inactivating factors.
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  21. Black, Jennifer A.; Thomson, Kenneth S., Device and direct method for detection of antibiotic-inactivating enzymes.
    상세보기
  22. Black,Jennifer A.; Moland,Ellen S.; Thomson,Kenneth, Device and method for detecting antibiotic inactivating enzymes.
    상세보기
  23. Black,Jennifer A.; Moland,Ellen S.; Thomson,Kenneth, Device and method for detecting antibiotic inactivating enzymes.
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  24. Black,Jennifer A.; Moland,Ellen S.; Thomson,Kenneth S., Device and method for detecting antibiotic inactivating enzymes.
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  25. Black,Jennifer A.; Thomson,Kenneth S., Device and method for detecting antibiotic-inactivating enzymes.
    상세보기
  26. Black,Jennifer A.; Moland,Ellen S.; Thomson,Kenneth, Device and method for determining antibiotic susceptibility.
    상세보기
  27. Wardlaw Stephen C., Disposable apparatus for determining antibiotic sensitivity of bacteria.
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  28. Mak, Puiying Annie; Santos, George; Janes, Jeffrey Eugene; Donnelly, John J., High-throughput complement-mediated antibody-dependent and opsonic bactericidal assays.
    상세보기
  29. Terreux, Raphael; Phipps, Jenny, Inhibitors of protein kinases and uses thereof.
    상세보기
  30. Riss,Terry L.; Moravec,Richard A., Kit for measuring cytotoxicity of a test agent.
    상세보기
  31. Wardlaw Stephen C., Method and apparatus for determining the sensitivity of a microorganism to a growth altering agent.
    상세보기
  32. Taintor,Read, Method for antimicrobial susceptibility testing of microorganisms.
    상세보기
  33. Nakano,Tomota; Kurihara,Makoto, Method for detecting microorganisms and detection kit.
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  34. Wardlaw Stephen C., Method for determining antibiotic sensitivity of bacteria.
    상세보기
  35. Stephen C. Wardlaw ; Robert A. Levine, Method for determining the effects of a growth-altering agent on a microbial colony.
    상세보기
  36. Sharpin, Rosemary Katherine Cameron, Micro-organism test apparatus and methods of using the same.
    상세보기
  37. Steiner, Sandra; Holder, Patricia F.; Carlone, George M.; Rajam, GowriSankar, Multiple-valent opsonophagocytic assay selection panel arrays and uses therefor.
    상세보기
  38. Susan R. Mikkelsen CA; Peter Ertl CA, Rapid electrochemical assay for antibiotic and cytotoxic drug susceptibility in microorganisms.
    상세보기
  39. Wiles, Timothy M.; Turner, David J.; O'Connell, Michael A.; Parmigiani, Giovanni; Clyde, Merlise, System and method for analyzing antibiotic susceptibility of biological samples using redox and turbidity measurments to ascertain minimum inhibitory concentrations (MICs).
    상세보기
  40. Stamler Jonathan S. ; Day Brian J. ; Gross Steven S. ; Griffith Owen W., Treatments based on discovery that nitric oxide synthase is a paraquat diaphorase.
    상세보기
  41. Horzempa, Joseph Andrew; Henson, Dawn Marie; Nau, Gerard Joseph, Use of resazurin, or analogs thereof, for antibacterial therapy.
    상세보기

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