이 특허를 인용한 특허 (110)

1. Prakash, Thazha P.; Baker, Brenda F.; Eldrup, Anne B.; Manoharan, Muthiah; Bhat, Balkrishen; Griffey, Richard; Swayze, Eric E.; Crooke, Stanley T., 2′-Fluoro substituted oligomeric compounds and compositions for use in gene modulations.

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2. Prakash, Thazha P.; Seth, Punit P.; Swayze, Eric E., 5′ modified nucleosides and oligomeric compounds prepared therefrom.

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3. Manoharan, Muthiah; Rajeev, Kallanthottathil G.; Zlatev, Ivan; Swayze, Eric E.; Prakash, Thazha P.; Lima, Walter F., 5′-end derivatives.

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4. Cairns, Belinda; Chen, Ruihuan; Frantz, Gretchen; Hillan, Kenneth J.; Koeppen, Hartmut; Phillips, Heidi S.; Polakis, Paul; Spencer, Susan D.; Smith, Victoria; Williams, P. Mickey; Wu, Thomas D.; Zhang, Zemin, Anti-TAT188 antibodies.

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5. Cairns, Belinda; Chen, Ruihuan; Frantz, Gretchen; Hillan, Kenneth J.; Koeppen, Hartmut; Phillips, Heidi S.; Polakis, Paul; Spencer, Susan D.; Smith, Victoria; Williams, P. Mickey; Wu, Thomas D.; Zhang, Zemin; Sakanaka, Chie; Chuntharapai, Anan; Reed, Chae Janeka, Antibody compositions for the diagnosis and treatment of tumor.

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6. Karelson, Mati; Saarma, Mart; Pilv, Mehis, Antisense agents combining strongly bound base-modified oligonucleotide and artificial nuclease.

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7. Bennett, C. Frank; Cowsert, Lex M.; Siwkowski, Andrew M., Antisense modulation of CD40 expression.

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8. Bornhop, Darryl J.; Mousa, Mina; Kussrow, Amanda, Backscattering interferometric methods.

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9. Fearon, Karen L., Branched immunomodulatory compounds and methods of using the same.

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10. Lisanti, Michael P.; Jasmin, Jean-Francois; Quann, Kevin, Caveolin-1 related methods for treating glioblastoma with temozolomide.

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11. Crooke, Stanley T., Chimeric oligomeric compounds and their use in gene modulation.

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12. Bennett, Clarence Frank; Ecker, David J.; Cook, Phillip Dan, Composition and methods for the pulmonary delivery of nucleic acids.

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13. Morris, David W.; Engelhard, Eric K., Compositions and methods for cancer.

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14. Morris, David W.; Engelhard, Eric K., Compositions and methods for cancer.

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15. Akinc, Akin; Nakayama, Tomoko; Manoharan, Muthiah; Stoffel, Markus, Compositions and methods for delivering RNAI using lipoproteins.

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16. Li, Dean; Jones, Christopher; London, Nyall, Compositions and methods for inhibiting vascular permeability.

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17. Akinc, Akin; Nakayama, Tomoko; Konys, David; Stoffel, Markus; Wolfrum, Christian, Compositions and methods for mediating RNAi in vivo.

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18. Teng, Ching-Leou; Cook, Phillip Dan; Tillman, Lloyd; Hardee, Gregory E.; Ecker, David J.; Manoharan, Muthiah, Compositions and methods for non-parenteral delivery of oligonucleotides.

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19. Teng, Ching-Leou; Cook, Phillip Dan; Tillman, Lloyd; Hardee, Gregory E.; Ecker, David J.; Manoharan, Muthiah, Compositions and methods for non-parenteral delivery of oligonucleotides.

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20. Teng, Ching-Leou; Cook, Phillip Dan; Tillman, Lloyd; Hardee, Gregory E.; Ecker, David J.; Manoharan, Muthiah, Compositions and methods for non-parenteral delivery of oligonucleotides.

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21. Mehta, Rahul C.; Hardee, Gregory E.; Cook, Phillip Dan; Ecker, David J.; Tsai, Yali Jennifer; Templin, Michael V., Compositions and methods for topical delivery of oligonucleotides.

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22. Li, Dean; Jones, Christopher; London, Nyall, Compositions and methods for treating ocular pathologic angiogenesis and vascular permeability.

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23. Morris, David W.; Engelhard, Eric K., Compositions and methods in cancer associated with altered expression of KCNJ9.

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24. Morris, David W.; Engelhard, Eric K., Compositions and methods in cancer associated with altered expression of PRLR.

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25. Dobie, Kenneth W.; Dean, Nicholas M.; Bennett, C. Frank, Compositions and their uses directed to HBXIP.

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26. Allerson, Charles; Bhat, Balkrishen; Eldrup, Anne B.; Manoharan, Muthiah; Griffey, Richard H.; Baker, Brenda F.; Swayze, Eric E., Compositions comprising alternating 2'-modified nucleosides for use in gene modulation.

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27. Allerson, Charles; Bhat, Balkrishen; Eldrup, Anne B.; Manoharan, Muthiah; Griffey, Richard H.; Baker, Brenda F.; Swayze, Eric E., Compositions comprising alternating 2′-modified nucleosides for use in gene modulation.

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28. Capaldi,Daniel C.; Gaus,Hans Joachim Josef; Rentel,Claus Andre Frank; Olsen,Philip Dmitri; Kurata,Christine C.; Song,Quanlai, Compounds and methods for the characterization of oligonucleotides.

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29. Bennett, C. Frank; McKay, Robert; Monia, Brett P.; Baker, Brenda F.; Sioufi, Namir, Conjugates for use in hepatocyte free uptake assays.

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30. Mirkin, Chad A.; Paller, Amy S.; Giljohann, David A., Delivery of oligonucleotide functionalized nanoparticles.

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31. Gunderson, Kevin; Stuelpnagel, John R.; Chee, Mark S., Detection of nucleic acid reactions on bead arrays.

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32. Gunderson, Kevin; Stuelpnagel, John R.; Chee, Mark S.; Fan, Jian-Bing, Detection of nucleic acid reactions on bead arrays.

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33. Gunderson, Kevin; Stuelpnagel, John R.; Chee, Mark S.; Fan, Jian-Bing, Detection of nucleic acid reactions on bead arrays.

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34. Carvalho,Maria da Gloria; Sampson,Jacquelyn S.; Ades,Edwin W.; Carlone,George; McCaustland,Karen, Development of a real-time PCR assay for detection of pneumococcal DNA and diagnosis of pneumococccal disease.

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35. Monia, Brett P.; Freier, Susan M.; Siwkowski, Andrew M.; Guo, Shuling, Diagnosis and treatment of disease.

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36. Kraynack, Bryan A.; Baker, Brenda F.; Bhat, Balkrishen; Swayze, Eric E.; Griffey, Richard H., Double stranded compositions comprising a 3′-endo modified strand for use in gene modulation.

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37. Baker, Brenda F.; Kraynack, Bryan A., Double stranded constructs comprising one or more short strands hybridized to a longer strand.

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38. Leeds Janet M. ; Cummins Lendell L., Fluorescence based nuclease assay.

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39. Swayze, Eric E.; Migawa, Michael T.; Wyrzykiewicz, Tadeusz Krzysztof, Gapped oligomeric compounds having linked bicyclic sugar moieties at the termini.

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40. Ko, Lan; Brooks, Yang Sui, Gene amplification of coactivator CoAA and uses thereof.

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41. Manoharan, Muthiah, Ligand-conjugated oligomeric compounds.

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42. Fu, Glenn K.; Shapero, Michael H.; Wang, Pei-Hua, Locus specific amplification using array probes.

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43. Lisanti, Michael P.; Sotgia, Federica, MCT protein inhibitor-related prognostic and therapeutic methods.

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44. Gilad, Shlomit; Meiri, Esther, Method for detecting a target nucleic acid comprising two portions using probes having a first portion complementary to the first portion of the target nucleic acid and a second portion substantially complementary to the second portion of the target nucleic acid.

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45. Gleave, Martin E.; Ischia, Joseph, Method for treatment of castration-resistant prostate cancer.

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46. Bennett Clarence Frank ; Manoharan Muthiah ; Hebert Normand ; Bhat Balkrishen, Methods and compounds for tracking the biodistribution of macromolecule-carrier combinations.

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47. Grasso, Luigi; Liang, Shaohong; Nicolaides, Nicholas C.; Sass, Philip M., Methods of generating high-production of antibodies from hybridomas created by in vitro immunization.

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48. Grasso, Luigi; Liang, Shaohong; Nicolaides, Nicholas C.; Sass, Philip M., Methods of generating high-production of antibodies from hybridomas created by in vitro immunization.

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49. Prakash, Thazha P.; Seth, Punit P.; Manoharan, Muthiah; Swayze, Eric E.; Rajeev, Kallanthottathil G.; Zlatev, Ivan, Modified 5′ diphosphate nucleosides and oligomeric compounds prepared therefrom.

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50. Bennett, C. Frank; Cowsert, Lex M.; Freier, Susan M., Modulation of CD40 expression.

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51. Bennett, C. Frank; Cowsert, Lex M.; Freier, Susan M., Modulation of CD40 expression.

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52. Dean Nicholas M. ; McKay Robert, Modulation of c-jun using inhibitors of protein kinase C.

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53. Monia, Brett P.; Bhanot, Sanjay; Dobie, Kenneth W.; Jain, Ravi, Modulation of eIF4E-BP1 expression.

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54. Bhanot, Sanjay; Dobie, Kenneth W.; Jain, Ravi, Modulation of eIF4E-BP2 expression.

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55. Bhanot, Sanjay; Dobie, Kenneth W.; Jain, Ravi, Modulation of eIF4E-BP2 expression.

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56. Bhanot,Sanjay; Dobie,Kenneth W.; Jain,Ravi, Modulation of eIF4E-BP2 expression.

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57. Brown-Driver, Vickie L.; Jain, Ravi, Modulation of transthyretin expression.

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58. Freier, Susan M., Modulation of transthyretin expression.

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59. Monia, Brett P.; Freier, Susan M.; Siwkowski, Andrew M.; Guo, Shuling, Modulation of transthyretin expression.

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60. Bornhop, Darryl J., Multiplexed interferometric detection system and method.

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61. Warthoe,Peter, Nano-mechanic microsensors and methods for detecting target analytes.

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62. Mirkin, Chad A.; Ko, Caroline H.; Stegh, Alexander; Giljohann, David A.; Luciano, Janina; Jensen, Samuel A., Nanoconjugates able to cross the blood-brain barrier.

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63. Wahlestedt, Claes, Natural antisense and non-coding RNA transcripts as drug targets.

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64. Bornhop, Darryl J.; Flowers, Robert A.; Miller, Esther Pesciotta, Nonaqueous backscattering interferometric methods.

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65. Mirkin, Chad A.; Giljohann, David A.; Seferos, Dwight, Nucleic acid functionalized nanoparticles for therapeutic applications.

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66. Mirkin, Chad A.; Rosi, Nathaniel L.; Thaxton, C. Shad; Giljohann, David A., Nucleic acid functionalized nanoparticles for therapeutic applications.

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67. Mirkin, Chad A.; Rosi, Nathaniel L.; Thaxton, C. Shad; Giljohann, David A., Nucleic acid functionalized nanoparticles for therapeutic applications.

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68. Mirkin, Chad A.; Rosi, Nathaniel L.; Thaxton, C. Shad; Giljohann, David A., Nucleic acid functionalized nonoparticles for therapeutic applications.

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69. Bentwich, Issac; Avniel, Amir; Aharonov, Ranit; Karov, Yael; Shemer-Avni, Yonat; Levy, Asal, Nucleic acids involved in viral infection.

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70. Andrei P. Guzaev ; Phillip Dan Cook ; Muthiah Manoharan ; Balkrishen Bhat, Nucleosidic and non-nucleosidic folate conjugates.

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71. Cook, Phillip Dan; Manoharan, Muthiah; Bhat, Balkrishen; Guzzaev, Andrei P., Nucleosidic and non-nucleosidic folate conjugates.

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72. Bhat, Balkrishen; Dande, Prasad; Prakash, Thazha P.; Allerson, Charles; Swayze, Eric E.; Griffey, Richard H., Oligomeric compounds comprising 4′-thionucleosides for use in gene modulation.

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73. Swayze, Eric E.; Siwkowski, Andrew M., Oligomeric compounds comprising bicyclic nucleosides and having reduced toxicity.

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74. Cook, Phillip Dan; Manoharan, Muthiah; Bhat, Balkrishen, Oligonucleotide analogs having modified dimers.

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75. Phillip Dan Cook ; Muthiah Manoharan ; Balkrishen Bhat, Oligonucleotide analogs having modified dimers.

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76. Albaek, Nanna; Hansen, Henrik Frydenlund; Kammler, Susanne; Ravn, Jacob; Orum, Henrik, Oligonucleotide conjugates.

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77. Moore,Max N.; Andrade,Mark; Carty,Recaldo; Scozzari,Anthony; Krotz,Achim, Oligonucleotide synthesis with alternative solvents.

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78. Cook, Phillip Dan; Manoharan, Muthiah; Bhat, Balkrishen, Oligonucleotide-folate conjugates.

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79. Manoharan, Muthiah, Oligonucleotides conjugated to protein-binding drugs.

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80. Crooke, Stanley T., Oligoribonucleotides and ribonucleases for cleaving RNA.

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81. Mirkin, Chad A.; Seferos, Dwight S.; Giljohann, David A., Particles for detecting intracellular targets.

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82. Mirkin, Chad A.; Seferos, Dwight; Giljohann, David A., Particles for detecting intracellular targets.

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83. Manoharan, Muthiah; Maier, Martin A., Peptide-conjugated oligomeric compounds.

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84. Anantharamaiah, Gattadahalli M.; Fogelman, Alan M.; Navab, Mohamad; Rudolf, Martin, Peptides and peptide mimetics to treat pathologies associated with eye disease.

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85. Mirkin, Chad A.; Giljohann, David A.; Seferos, Dwight S.; Prigodich, Andrew E.; Patel, Pinal C., Polyvalent RNA-nanoparticle compositions.

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86. Mirkin, Chad A.; Giljohann, David A.; Seferos, Dwight; Prigodich, Andrew E.; Patel, Pinal C., Polyvalent RNA-nanoparticle compositions.

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87. Bhat, Balkrishen; Swayze, Eric E.; Prakash, Thazha P.; Allerson, Charles; Dande, Prasad; Griffey, Richard H., Positionally modified siRNA constructs.

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88. Bornhop, Darryl J.; Kammer, Michael, Robust interferometer and methods of using same.

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89. Anantharamaiah, Gattadahalli M.; Garber, David W.; Datta, Geeta; Handattu, Sheila P.; Mishra, Vinod K., Synthetic apolipoprotein E mimicking polypeptides and methods of use.

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90. Anantharamaiah, Gattadahalli M.; White, C. Roger; Gupta, Himanshu, Synthetic apolipoprotein E mimicking polypeptides and methods of use.

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91. Cowsert,Lex M.; Baker,Brenda F.; McNeil,John; Freier,Susan M.; Sasmor,Henri M.; Brooks,Douglas G.; Ohashi,Cara; Wyatt,Jacqueline R.; Borchers,Alexander H.; Vickers,Timothy A., System of components for preparing oligonucleotides.

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92. Donald, Carlton D., Targeting PAX2 for the induction of DEFB1-mediated tumor immunity and cancer therapy.

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93. Donald, Carlton D., Targeting PAX2 for the induction of DEFB1-mediated tumor immunity and cancer therapy.

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94. Donald, Carlton D., Targeting PAX2 for the induction of DEFB1-mediated tumor immunity and cancer therapy.

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95. Donald, Carlton D., Targeting PAX2 for the treatment of breast cancer.

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96. Donald, Carlton D., Targeting PAX2 for the treatment of breast cancer.

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97. Donald, Carlton D., Targeting PAX2 for the treatment of breast cancer.

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98. Donald, Carlton D., Targeting PAX2 for the treatment of breast cancer.

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99. Mirkin, Chad A.; Giljohann, David A.; Daniel, Weston L.; Cutler, Joshua I.; Zhang, Ke; Zheng, Dan, Templated nanoconjugates.

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100. Mirkin, Chad A.; Giljohann, David A.; Daniel, Weston L.; Cutler, Joshua I.; Zhang, Ke; Zheng, Dan, Templated nanoconjugates.

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101. Morris, David W.; Malandro, Marc S., Therapeutic targets in cancer.

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102. Morris, David W.; Malandro, Marc S., Therapeutic targets in cancer.

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103. Cavanaugh, Shanti A.; Crowley, Mark A.; Spatz, Neil J., Thermal control system for liquid crystal cell.

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104. Faghihi, Mohammad Ali; Coito, Carlos, Treatment of brain derived neurotrophic factor (BDNF) related diseases by inhibition of natural antisense transcript to BDNF.

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105. Hanash, Samir M.; Rickman, David; Tyagi, Rachana; Zhu, Xiao-Xiang; Kish, Phillip, Treatments and markers for cancers of the central nervous system.

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106. Chee, Mark S.; Dickinson, Todd A.; Gunderson, Kevin; O'Neil, Don, Use of microfluidic systems in the detection of target analytes using microsphere arrays.

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107. Chee, Mark S.; Dickinson, Todd A.; Gunderson, Kevin; O'Neil, Don, Use of microfluidic systems in the detection of target analytes using microsphere arrays.

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108. Chee, Mark S.; Dickinson, Todd A.; Gunderson, Kevin; O'Neil, Don; Stuelpnagel, John R., Use of microfluidic systems in the detection of target analytes using microsphere arrays.

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109. Bowman, Christopher N.; Rowlen, Kathy; Sikes, Hadley; Hansen, Ryan; Avens, Heather Jean, Use of photopolymerization for amplification and detection of a Molecular Recognition Event.

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110. Rowlen,Kathy L.; Birks,John W.; Bowman,Christopher; Sikes,Hadley; Hansen,Ryan; Kuchta,Robert, Use of photopolymerization for amplification and detection of a molecular recognition event.

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