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Isolated antigenic oncogene peptide fragments and uses 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-038/08
  • C07K-004/12
출원번호 US-0195075 (1994-02-10)
발명자 / 주소
  • Eberlein Timothy J. (Dover MA) Peoples George E. (Newtonville MA) Yoshino Ichiro (Brookline MA) Goedegebuure Peter (Brighton MA)
출원인 / 주소
  • Brigham and Women\s Hospital (Boston MA 02)
인용정보 피인용 횟수 : 40  인용 특허 : 0

초록

An isolated antigenic peptide fragment that is an isolated oncogene protein fragment is disclosed. The isolated peptide fragment of the invention is a peptide either 9 or 10 amino acid residues in length that includes at least a leucine residue at the C- terminus (i.e., position 9 or position 10). T

대표청구항

An isolated peptide consisting of 10 amino acid residues, said isolated peptide having an amine acid sequence consisting of IISAVVGILN, where N is an amine acid selected from the group consisting of L, V, and I.

이 특허를 인용한 특허 (40)

  1. Majumdar,Adhip P. N.; Sarkar,Fazlul H., Antibodies to a novel EGF-receptor related protein (ERRP).
  2. An Gang ; O'Hara S. Mark ; Ralph David ; Veltri Robert, Biomarkers and targets for diagnosis, prognosis and management of prostate, breast and bladder cancer.
  3. Singh, Harpreet; Emmerich, Niels; Hilf, Nobert; Walter, Steffen; Weinschenk, Toni, Combination therapy using active immunotherapy.
  4. Ioannides, Constantin G.; Campbell, Martin L.; O'Brian, Catherine A.; Peoples, George E., Controlled modulation of amino acid side chain length of peptide antigens.
  5. Ioannides, Constantin G.; Campbell, Martin L.; O'Brian, Catherine A.; Peoples, George E., Controlled modulation of amino acid side chain length of peptide antigens.
  6. Berd, David; Erdile, Lorne F.; Mokyr, Margalit B., Cryopreservation of haptenized tumor cells.
  7. Herlyn, Dorothee, Cytolytic T-cell clones against colorectal carcinoma.
  8. Heanue, Joseph Anthony; Funk, Tobias; Bechtel, Kate LeeAnn; Parashar, Amish, Identification of surgical smoke.
  9. Cheever, Martin A; Disis, Mary L, Immune reactivity to HER-2/protein for diagnosis and treatment of malignancies in which the HER-2/oncogene is associated.
  10. Spencer, David; Hanks, Brent; Slawin, Kevin, Induced activation in dendritic cells.
  11. Spencer, David; Hanks, Brent; Slawin, Kevin, Induced activation in dendritic cells.
  12. Spencer, David; Hanks, Brent; Slawin, Kevin, Induced activation in dendritic cells.
  13. Kundig,Thomas M.; Simard,John L., Method of inducing a CTL response.
  14. Kündig, Thomas M.; Simard, John J. L., Method of inducing a CTL response.
  15. Spencer, David; Narayanan, Priyadharshini, Methods and compositions for generating an immune response by inducing CD40 and pattern recognition receptor adapters.
  16. Spencer, David; Narayanan, Priyadharshini, Methods and compositions for generating an immune response by inducing CD40 and pattern recognition receptor adapters.
  17. Spencer, David; Narayanan, Priyadharshini, Methods and compositions for generating an immune response by inducing CD40 and pattern recognition receptor adapters.
  18. Spencer, David M; Lapteva, Natalia, Methods and compositions for generating an immune response by inducing CD40 and pattern recognition receptors and adaptors thereof.
  19. Spencer, David; Foster, Aaron Edward; Slawin, Kevin, Methods for controlling T cell proliferation.
  20. Slawin, Kevin; Spencer, David; Foster, Aaron Edward, Methods for inducing partial apoptosis using caspase polypeptides.
  21. Brenner, Malcolm K., Methods for inducing selective apoptosis.
  22. Brenner, Malcolm K., Methods for inducing selective apoptosis.
  23. Wallen Erik S. ; Moseley Pope L., Methods for synthesizing heat shock protein complexes.
  24. Erik Wallen ; Pope L. Moseley, Methods for using heat shock proteins.
  25. Spencer, David; Chang, Wei-Chun, Modified Caspase polypeptides and uses thereof.
  26. Spencer, David; Chang, Wei-Chun, Modified caspase polypeptides and uses thereof.
  27. Kikuchi Kokichi,JPX ; Sato Noriyuki,JPX ; Sahara Hiromitsu,JPX ; Yasojima Takahiro,JPX ; Wada Yoshimasa,JPX ; Suzuki Manabu,JPX ; Hamuro Junji,JPX, Peptide capable of inducing immune response to human gastric cancer and agent for preventing or treating human gastric c.
  28. Kokichi Kikuchi JP; Noriyuki Sato JP; Hiromitsu Sahara JP; Takahiro Yasojima JP; Yoshimasa Wada JP; Manabu Suzuki JP; Junji Hamuro JP, Peptide capable of inducing immune response to human gastric cancer and agent for preventing or treating human gastric cancer, containing the peptide.
  29. Kast,Wybe Martin; Melief,Cornelis Joseph Maria; Sette,Alessandro D.; Sidney,John C., Peptides of human Papilloma virus for use in human T cell response inducing compositions.
  30. Majumdar, Adhip P. N., Recombinant DNA encoding an epidermal growth factor receptor related protein.
  31. Ponniah, Sathibalan; Peoples, George E.; Storrer, Catherine E.; Flora, Michael, Stable quantitation and detection of immune response levels with non-zero background peptides.
  32. Subjeck, John R.; Henderson, Robert A.; Repasky, Elizabeth A.; Kazim, Latif; Wang, Xiang-Yang, Stress protein compositions and methods for prevention and treatment of cancer and infectious disease.
  33. Subjeck,John R.; Henderson,Robert A.; Repasky,Elizabeth A.; Kazim,Latif; Wang,Xiang Yang, Stress protein compositions and methods for prevention and treatment of cancer and infectious disease.
  34. Heemskerk, Mirjam H. M.; Falkenburg, J. H. Frederik, T cell receptors directed against Bob1 and uses thereof.
  35. Ponniah, Sathibalan; Peoples, George E.; Storrer, Catherine E.; Flora, Michael, Targeted identification of immunogenic peptides.
  36. Ponniah, Sathibalan; Peoples, George E.; Storrer, Catherine E.; Flora, Michael, Targeted identification of immunogenic peptides.
  37. Ponniah, Sathibalan; Peoples, George E; Storrer, Catherine E; Flora, Michael, Targeted identification of immunogenic peptides.
  38. Ponniah, Sathibalan; Peoples, George E; Storrer, Catherine E; Flora, Michael, Targeted identification of immunogenic peptides.
  39. Peoples, George; Ponniah, Sathibalan, Vaccine for the prevention of breast cancer recurrence.
  40. Peoples, George; Ponniah, Sathibalan, Vaccine for the prevention of breast cancer recurrence.
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