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Recombinant antibodies specific for a growth factor receptor 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C07K-016/28
  • C07K-016/46
  • C12N-015/62
출원번호 US-0235838 (1994-04-29)
우선권정보 EP-0810079 (1991-02-05)
발명자 / 주소
  • Wels Winfried S. (Basel CHX) Hynes Nancy E. (Basel CHX) Harweth Ina-Maria (Grenzach-Wyhlen DEX) Groner Bernd (Basel CHX) Hardman Norman (Riehen CHX) Zwickl Markus (Basel CHX)
출원인 / 주소
  • Ciba-Geigy Corporation (Tarrytown NY 02)
인용정보 피인용 횟수 : 184  인용 특허 : 0

초록

The invention concerns recombinant antibodies directed to the extracellular domain of the human growth factor receptor c-erbB-2 comprising a light chain variable domain and a heavy chain variable domain of a monoclonal antibody, monoclonal antibodies directed to c-erbB-2 themselves, a method of manu

대표청구항

A recombinant antibody directed to the extracellular domain of the growth factor receptor c-erbB-2 comprising of heavy chain variable domain and a light chain variable domain of a monoclonal antibody, wherein the heavy chain variable domain comprises a polypeptide of the formula FR1-CDR1H-FR2-CDR2H-

이 특허를 인용한 특허 (184)

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