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Biocompatible, surface modified materials 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61F-002/16
출원번호 US-0048036 (1993-04-14)
발명자 / 주소
  • Kamel Ihab (Drexel Hill PA) Soll David B. (Rydal PA)
출원인 / 주소
  • Drexel University (Philadelphia PA 02) Ophthalmic Research Corporation (Philadelphia PA 02)
인용정보 피인용 횟수 : 11  인용 특허 : 47

초록

A method of permanently modifying the surface of a substrate material so as to develop a microscopically smooth, biocompatible surface thereon comprises covalently grafting a biocompatible polymeric material to the surface of the substrate material by radio frequency plasma-induced grafting. The bio

대표청구항

A prosthesis for use in mammals comprising a polymeric substrate material having a permanently modified microscopically smooth, biocompatible surface thereon, produced by covalently grafting a polymeric biocompatible material to the surface of the substrate material by radio frequency plasma inducti

이 특허에 인용된 특허 (47)

  1. Guire Patrick E. (Eden Prairie MN), Biocompatible coating for solid surfaces.
  2. Highgate Donald J. (“Brambles,”Wonham Way Gomshall ; Guildford ; Surrey EN), Bioimplantable device from crosslinked, swollen, hydrophilic polymers.
  3. Galin Miles A. (823 United Nations Plaza New York NY 10017), Coated intraocular lens.
  4. Morley ; John R. ; Howe ; Ralph E., Coating a substrate by glow discharge graft polymerization.
  5. Karakelle Mutlu (Dayton OH) Zdrahala Richard J. (Miami Lakes FL), Composite membrane, method for its preparation and electrolyte sensor including same.
  6. Hfer Peter (Aschaffenburg DEX) Mller Ulrich (Johannesberg DEX) Brenz Manfred (Dreieich DEX) Schfer Horst (Aschaffenburg-Obernau DEX) Mller-Lierheim Wolfgang (Aschaffenburg DEX), Contact lens and compositions.
  7. Merrill ; Edward W., Contact lens having a smooth surface layer of a hydrophilic polymer.
  8. Lindstrom Richard L. (20050 Lakeview Ave. Excelsior MN 55331), Corneal implant lens with fixation holes.
  9. Pinchuk Leonard (Miami FL), Crack prevention of implanted prostheses.
  10. Karwoski Theodore (Nashua NH) Matsuzawa Yasuo (Nashua NH), Glow discharge process for producing implantable devices.
  11. Tighe Brian J. (Birmingham GB2) Gee Howard J. (Derbyshire GB2), Hydrogel-forming polymeric materials.
  12. Wolfson ; Leonard G., Hydrophilic contact lens case.
  13. Urbach Jacques (North Hollywood CA), Hydrophilic contact lens material.
  14. Loshaek Samuel (Chicago IL) Shen Chah M. (Chicago IL), Hydrophylic contact lenses and methods for making same.
  15. McAuslan Brian R. (Clareville Beach AUX), Implantable materials.
  16. Stoy Vladimir (Princeton NJ), Intraocular lenses.
  17. Galin Miles A. (115 E. 38th St. New York NY 10016), Medicament coated intraocular lens.
  18. Ueno, Susumu; Nomura, Hirokazu, Method for improving surface properties of a shaped article of a synthetic resin.
  19. Imada Kiyoshi (Omiya JPX) Ueno Susumu (Ibaraki JPX) Nishina Yasuhide (Ibaraki JPX) Nomura Hirokazu (Ibaraki JPX), Method for modifying surface properties of a shaped article of a silicone.
  20. Imada Kiyoshi (Omiya JPX) Ueno Susumu (Ibaraki JPX) Nishina Yasuhide (Ibaraki JPX) Nomura Hirokazu (Ibaraki JPX), Method for modifying surface properties of shaped articles of polymeric materials with low temperature plasma.
  21. Aelion Rene (Concord MA) Ferezy Edward (Merrick NY), Method for preparing hydrophilic polymers and polymer grafts including irradiation.
  22. Williams Joel L. (Cary NC) Montgomery David B. (Cary NC) Baldwin Lillian P. (Durham NC), Method for rapid adherence of endothelial cells onto a surface and surfaces prepared thereby.
  23. Hu Can B. (Spring Valley OH) Solomon Donald D. (Spring Valley OH) Shields Nancy L. (Dayton OH), Method for rendering a substrate surface antithrombogenic.
  24. Hfer Peter (Aschaffenburg Kleinwallstadt DEX) Kohl Wolfgang (Kleinwallstadt DEX), Method for surface treatment of contact lenses.
  25. Masso Jon D. (Whitinsville MA) Brennan William D. (Woodstock CT) Rotenberg Don H. (Westboro MA), Method imparting anti-static, anti-reflective properties to ophthalmic lenses.
  26. Halpern Gergory (Wilson Park Dr. Tarrytown NY 10591) Campbell Charles (Highwood Pl. Alpine NJ 07620) Beavers Ellington M. (931 Coates Rd. Meadowbrook PA 19046) Chen Huk Y. (42-01 Auburndale La. Flush, Method of hydrophilic coating of plastics.
  27. Chirila Traian V. (Hillarys AUX) Constable Ian J. (Mosman Park AUX) Cooper Richard L. (Mount Claremont AUX), Method of making photoprotective hydrophilic polymers and ocular devices thereof.
  28. Goldberg Eugene P. (Gainesville FL) Burns Jim (Natick MA) Sheets John W. (Pasadena CA) Larson Jeffrey A. (Pasadena CA) Kumar Sudesh (New Bombay CT INX) Osborn David (Stamford CT), Ocular implants and methods for their manufacture.
  29. Fletcher James C. Administrator of the National Aeronautics and Space Administration ; with respect to an invention of ( Sunnyvale CA) Wydeven ; Jr. Theodore J. (Sunnyvale CA) Hollahan John R. (San F, Oxygen post-treatment of plastic surfaces coated with plasma polymerized silicon-containing monomers.
  30. Hoffman Allan S. (King County WA) Garfinkle Andrew (King County WA) Ratner Buddy D. (King County WA) Hanson Stephen R. (San Diego County CA), Plasma gas discharge treatment for improving the biocompatibility of biomaterials.
  31. Hu Can B. (Dayton OH) Solomon Donald D. (Spring Valley OH), Polymeric articles having enhanced antithrombogenic activity.
  32. Ratner Buddy D. (Seattle WA) Mateo Nancy B. (Seattle WA), Polymeric intraocular lens material having improved surface properties.
  33. Guire Patrick E. (Eden Prairie MN) Dunkirk Shawn G. (Eden Prairie MN) Josephson Mark W. (Richfield MN) Swanson Melvin J. (Carver MN), Preparation of polymeric surfaces via covalently attaching polymers.
  34. Nowlin ; Thomas E. ; Martineau ; Ronald A., Process for chemically bonding a poly-p-xylylene to a thermosetting resin and article produced thereby.
  35. Kubacki ; Ronald M., Process for producing a well-adhered durable optical coating on an optical plastic substrate.
  36. Chen Richard Y. (Webster NY), Process for putting a hydrophilic coating on a hydrophobic contact lens.
  37. Feneberg Paul (Planegg DT) Krekeler Ulrich (Munich DT), Process for the production of hydrophilic surfaces on silicon elastomer articles.
  38. Horbett Thomas A. (Seattle WA) Ratner Buddy D. (Seattle WA) Chinn Joseph A. (Seattle WA) Haque Yasmeen (Pasadena CA), Radio frequency plasma deposited polymers that enhance cell growth.
  39. Feneberg Paul (Planegg DT) Krekeler Ulrich (Munich DT), Silicone contact lens with hydrophilic surface treatment.
  40. Peyman Gholam A. (1044 N. Oak Park Ave. Oak Park IL 60302) Koziol Jeffrey E. (249 Sunset Palatine IL 60067) Yasuda Hirotsugu (Rte. 3 ; Box 98 Newburg MO 65550), Soft corneal contact lens with tightly cross-linked polymer coating and method of making same.
  41. Levy Boris (Wayland MA), Surface modification by electrical discharge in a mixture of gases.
  42. Ratner Buddy D. (Seattle WA) Tidwell Caren L. (J.C. Arnhem NLX), Surface-modified self-passivating intraocular lenses.
  43. Muehlberger Erich (San Clemente CA) Kremith Roland D. (Newport Beach CA), System and method for plasma coating.
  44. Lidel ; Darrel D., Treating polymeric surfaces.
  45. Feurer Bernard (Saint Orens de Gameville FRX) Baronet Philippe (Toulouse FRX), Treatment process for rendering corneal contact lenses hydrophilic.
  46. Karwoski Theodore (Nashua NH) Matsuzawa Yasuo (Nashua NH), Vascular prosthesis having fluorinated coating with varying F/C ratio.
  47. Deichert William G. (Macedon NY) Niu Gregory C. (Lexington MA) VanBuren Martin F. (Chelmsford MA), Water absorbing contact lenses made from polysiloxane/acrylic acid polymer.

이 특허를 인용한 특허 (11)

  1. Belcher, William Randal; Clapp, Mannie Lee; Datta, Saswati; El-Nokaly, Magda; Murawski, Sandra Lou; Page, Steven Hardy; Paldey, Sohini; Warner, Ronald Ray; Warren, Raphael, Coated substrate with properties of keratinous tissue.
  2. Ding Ni ; Raeder-Devens Jennifer E. ; Trinh Tuyethoa Thi, Drug-releasing coatings for medical devices.
  3. LeBoeuf Albert R. ; Green George ; Piper Barbara A., Method for reducing taciness of soft acrylic polymers.
  4. Kelleher Peter Joseph, Methods and compositions for the modulation of cell proliferation and wound healing.
  5. Barak,Lawrence S.; Caron,Marc G.; Ferguson,Stephen S.; Zhang,Jie, Methods of assaying receptor activity.
  6. Barak, Lawrence S.; Caron, Marc G.; Ferguson, Stephen S.; Zhang, Jie, Methods of assaying receptor activity and constructs useful in such methods.
  7. Barak, Lawrence S.; Caron, Marc G.; Ferguson, Stephen S.; Zhang, Jie, Methods of assaying receptor activity and constructs useful in such methods.
  8. Kelleher Peter J., Modulation of cell proliferation and wound healing.
  9. Bratty, Michael; Lawrence, Rick; Kratochvil, David, Nickel sulphide precipitation process.
  10. Fishman Steven J., Radiation protective device.
  11. Barak, Lawrence S.; Shetzline, Michael A.; Oakley, Robert H.; Caron, Marc G., Single-cell biosensor for the measurement of GPCR ligands in a test sample.
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