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Mucosal adhesive device for long-acting delivery of pharmaceutical combinations in oral cavity 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/20
출원번호 US-0160474 (1993-12-01)
발명자 / 주소
  • Chien Yie W. (North Brunswick NJ) Nair Mona (Highland Park NJ)
출원인 / 주소
  • Rutgers, The State University of New Jersey (New Brunswick NJ 02)
인용정보 피인용 횟수 : 91  인용 특허 : 9

초록 ▼

Mucosal adhesive devices are provided for use in the oral cavity for therapy against infections. The devices are dosage units which comprise a combination of antimicrobial agents such as antifungal agents and anti-inflammatory agents, optionally also a local anesthetic. The dosage units yield a grad

대표청구항 ▼

A mucosal adhesive dosage unit adapted to use for treatment of oral cavity infection selected from a) the forms consisting of a dosage unit wherein mucoadhesive polymer layer having intermixed pharmaceuticals is adhered to a protective backing layer, and b) a tablet comprising a mucosal adhesive pol

이 특허에 인용된 특허 (9)

  1. Schiraldi Michael T. (East Brunswick NJ) Perl Martin M. (Brooklyn NY) Rubin Howard (Rockaway NJ), Bioadhesive extruded film for intra-oral drug delivery and process.
    상세보기
  2. Pomerantz Edwin (Woodland Hills CA), Compositions and in situ methods for forming films on body tissue.
    상세보기
  3. Pomerantz Edwin (Woodland Hills CA), Compositions and in situ methods for forming films on body tissue.
    상세보기
  4. Mantelle Juan A. (Miami FL), Compositions and methods for topical administration of pharmaceutically active agents.
    상세보기
  5. Nagai Tsuneji (Chofu JPX) Machida Yoshiharu (Kawasaki JPX) Suzuki Yoshiki (Hino JPX) Ikura Hiroshi (Hino JPX), Method and preparation for administration to the mucosa of the oral or nasal cavity.
    상세보기
  6. Sanvordeker Dilip R. (Irvine CA) Leung Sau-Hung S. (Corona CA), Mucoadhesive carrier for delivery of therapeutical agent.
    상세보기
  7. Friedman Michael (Jerusalem ILX), Oral antifungal preventative, and method of use.
    상세보기
  8. Repka Michael A. (Pleasanton TX) Gerding Thomas G. (Georgetown TX), Polyethylene glycol ointment for apthous ulcers.
    상세보기
  9. Yukimatsu Keiji (Otsu JPX) Kakumoto Munetaka (Otsu JPX) Yasuda Yoshihisa (Otsu JPX) Tsujimoto Junko (Otsu JPX) Sogabe Masae (Uji JPX), Sustained-release preparation applicable to mucous membrane in oral cavity.
    상세보기

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  6. Tamarkin, Dov; Friedman, Doron; Eini, Meir; Besonov, Alex; Shifrin, Helena, Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof.
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