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Methods of determining chemicals that modulate transcriptionally expression of genes associated with cardiovascular dise 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12P-019/34
  • C12Q-001/68
출원번호 US-0832905 (1992-02-07)
발명자 / 주소
  • Foulkes J. Gordon (Huntington Station NY) Liechtfried Franz E. (Vienna ATX) Pieler Christian (Vienna ATX) Stephenson John R. (Santa Cruz CA) Case Casey C. (Lynbrook NY)
출원인 / 주소
  • Oncogene Science, Inc. (Uniondale NY 02)
인용정보 피인용 횟수 : 68  인용 특허 : 0

초록

The invention provided for a method of directly and specifically transcriptionally modulating the expression of a gene encoding a protein of interest associated with treatment of one or more symptoms of a cardiovascular disease such as atherosclerosis, restenosis or hypertension. Further provided is

대표청구항

A method of determining whether a chemical not previously known to be a modulator of protein biosynthesis is capable of specifically transcriptionally modulating the expression of a gene encoding a protein of interest associated with the treatment of one or more symptoms of a cardiovascular disease

이 특허를 인용한 특허 (68)

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  25. Brown, James F.; Silver, Jonathan E., Method and device for detecting the presence of a single target nucleic acid in a sample.
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  35. Zhang, Lixin Lilly; Youngquist, Robert Scott, Method of treating hair loss using diphenylether derivatives.
  36. Zhang, Lixin Lilly; Youngquist, Robert Scott, Method of treating hair loss using diphenylmethane derivatives.
  37. Zhang, Lixin Lilly; Youngquist, Robert Scott, Method of treating hair loss using sulfonyl thyromimetic compounds.
  38. Buechler, Kenneth F., Methods and compositions for measuring natriuretic peptides and uses thereof.
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  44. Billiar Timothy R. ; Tzeng Edith ; Shears ; II Larry L. ; Geller David A. ; Edington Howard David James, Methods for promoting wound healing and treating transplant-associated vasculopathy.
  45. Stylli, Chari; Beckey, Samuel S.; Shumate, Christopher Bentley; Coassin, Peter J., Methods for rapidly identifying useful chemicals in liquid sample.
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  47. Glynne, Richard; Goodnow, Chris; Mack, David, Methods of screening for B cell activity modulators.
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  52. Conkling,Mark; Li,Yan, Putrescine-n-methyltransferase promoter.
  53. Oscar L. Acevedo ; Martin G. Dunkel DE; Phillip Dan Cook, Pyrimidine nucleosides.
  54. Conkling, Mark A.; Song, Wen; Mendu, Nandini, Regulation of quinolate phosphoribosyl transferase expression.
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  61. Youngquist, Robert Scott; McIver, John McMillan, Sulfur-containing thyroxane derivatives and their use as hair growth promotors.
  62. Chari Stylli ; Samuel S. Beckey ; Christopher Bentley Shumate ; Peter J. Coassin, Systems and methods for rapidly identifying useful chemicals in liquid samples.
  63. Chari Stylli ; Samuel S. Beckey ; Christopher Bentley Shumate ; Peter J. Coassin, Systems and methods for rapidly identifying useful chemicals in liquid samples.
  64. Stylli Chari ; Beckey Samuel S. ; Shumate Christopher Bentley ; Coassin Peter J., Systems and methods for rapidly identifying useful chemicals in liquid samples.
  65. Stylli, Chari; Beckey, Samuel S.; Shumate, Christopher Bentley; Coassin, Peter J., Systems and methods for rapidly identifying useful chemicals in liquid samples.
  66. Conkling, Mark A.; Song, Wen; Mendu, Nandini, Tobacco products with increased nicotine.
  67. Conkling, Mark A.; Song, Wen; Mendu, Nandini, Tobacco products with reduced nicotine.
  68. Dahlen, Jeffrey R.; Buechler, Kenneth F.; Valkirs, Gunars E., Use of B-type natriuretic peptide as a prognostic indicator in acute coronary syndromes.
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